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Acta Oto-Laryngologica Volume 140, 2020 - Issue 3
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Mouth/Pharynx

Overall assessment of tumor-infiltrating lymphocytes in head and neck squamous cell carcinoma: time to take notice

Alhadi AlmangushDepartment of Pathology, University of Helsinki, Helsinki, Finland; ;Research Program in Systems Oncology, Faculty of Medicine, University of Helsinki, Helsinki, Finland; ;Institute of Biomedicine, Pathology, University of Turku, Turku, Finland; ;Faculty of Dentistry, University of Misurata, Misurata, Libya;
,
Ilmo LeivoInstitute of Biomedicine, Pathology, University of Turku, Turku, Finland;
&
Antti A. MäkitieDepartment of Otorhinolaryngology, Head and Neck Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; ;Research Program in Systems Oncology, Faculty of Medicine, University of Helsinki, Helsinki, Finland; ;Division of Ear, Nose and Throat Diseases, Department of Clinical Sciences, Intervention and Technology, Karolinska Institutet and Karolinska Hospital, Stockholm, SwedenCorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0002-0451-2404
ORCID Icon
Pages 246-248 | Received 05 Nov 2019, Accepted 16 Jan 2020, Published online: 05 Feb 2020

References

  • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011;144(5):646–674.
  • Zhang XM, Song LJ, Shen J, et al. Prognostic and predictive values of immune infiltrate in patients with head and neck squamous cell carcinoma. Hum Pathol. 2018;82:104–112.
  • Hendry S, Salgado R, Gevaert T, et al. Assessing tumor-infiltrating lymphocytes in solid tumors: a practical review for pathologists and proposal for a standardized method from the International Immuno-Oncology Biomarkers Working Group: Part 2: TILs in Melanoma, gastrointestinal tract carcinomas, non-small cell lung carcinoma and mesothelioma, endometrial and ovarian carcinomas, squamous cell carcinoma of the head and neck, genitourinary carcinomas, and primary brain tumors. Adv Anat Pathol. 2017;24(6):311–335.
  • James FR, Jiminez-Linan M, Alsop J, et al. Association between tumour infiltrating lymphocytes, histotype and clinical outcome in epithelial ovarian cancer. BMC Cancer. 2017;17(1):657.
  • Jakubowska K, Kisielewski W, Kanczuga-Koda L, et al. Stromal and intraepithelial tumor-infiltrating lymphocytes in colorectal carcinoma. Oncol Lett. 2017;14:6421–6432.
  • Okadome K, Baba Y, Yagi T, et al. Prognostic nutritional index, tumor-infiltrating lymphocytes, and prognosis in patients with esophageal cancer. Ann Surg. 2018;1. Epub ahead of print.
  • Rakaee M, Kilvaer TK, Dalen SM, et al. Evaluation of tumor-infiltrating lymphocytes using routine H&E slides predicts patient survival in resected non-small cell lung cancer. Hum Pathol. 2018;79:188–198.
  • Ward MJ, Thirdborough SM, Mellows T, et al. Tumour-infiltrating lymphocytes predict for outcome in HPV-positive oropharyngeal cancer. Br J Cancer. 2014;110(2):489–500.
  • Ruangritchankul K, Sandison A, Warburton F, et al. Clinical evaluation of tumour-infiltrating lymphocytes as a prognostic factor in patients with human papillomavirus-associated oropharyngeal squamous cell carcinoma. Histopathology. 2019;75(1):146–150.
  • Heikkinen I, Bello IO, Wahab A, et al. Assessment of tumor-infiltrating lymphocytes predicts the behavior of early-stage oral tongue cancer. Am J Surg Pathol. 2019;43(10):1392–1396.
  • Faraji F, Fung N, Zaidi M, et al. Tumor-infiltrating lymphocyte quantification stratifies early-stage human papillomavirus oropharynx cancer prognosis. Laryngoscope. 2019. Epub ahead of print.
  • Xu Q, Wang C, Yuan X, et al. Prognostic value of tumor-infiltrating lymphocytes for patients with head and neck squamous cell Carcinoma. Transl Oncol. 2017;10(1):10–16.
  • Wang J, Wang S, Song X, et al. The prognostic value of systemic and local inflammation in patients with laryngeal squamous cell carcinoma. Onco Targets Ther. 2016; 9:7177–7185.
  • Wang YQ, Chen YP, Zhang Y, et al. Prognostic significance of tumor-infiltrating lymphocytes in non-disseminated nasopharyngeal carcinoma: a large-scale cohort study. Int J Cancer. 2018;142(12):2558–2566.
  • Almangush A, Ruuskanen M, Hagstrom J, et al. Tumor-infiltrating lymphocytes associate with outcome in nonendemic nasopharyngeal carcinoma: a multicenter study. Hum Pathol. 2018;81:211–219.
  • Miyauchi S, Kim SS, Pang J, et al. Immune modulation of head and neck squamous cell carcinoma and the tumor microenvironment by conventional therapeutics. Clin Cancer Res. 2019;25(14):4211–4223.
  • Topalian SL, Hodi FS, Brahmer JR, et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med. 2012;366(26):2443–2454.
  • Dieci MV, Radosevic-Robin N, Fineberg S, et al. Update on tumor-infiltrating lymphocytes (TILs) in breast cancer, including recommendations to assess TILs in residual disease after neoadjuvant therapy and in carcinoma in situ: a report of the International Immuno-Oncology Biomarker Working Group on Breast Cancer. Semin Cancer Biol. 2018;52:16–25.
  • Wang S, Yang DM, Rong R, et al. Pathology image analysis using segmentation deep learning algorithms. Am J Pathol. 2019;189(9):1686–1698.
  • Shaban M, Khurram SA, Fraz MM, et al. A novel digital score for abundance of tumour infiltrating lymphocytes predicts disease free survival in oral squamous cell carcinoma. Sci Rep. 2019;9(1):13341.

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