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Acta Oto-Laryngologica Volume 142, 2022 - Issue 6
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Nose/Sinus

Identifying chronic rhinosinusitis without nasal polyps by analyzing aspirated nasal air with an electronic nose based on differential mobility spectrometry

Jussi Virtanena Department of Otorhinolaryngology, Head and Neck Surgery, Tampere University Hospital, Tampere, Finland;b Faculty of Medicine and Health Technology, Tampere University, Tampere, FinlandCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-0853-216XView further author information
ORCID Icon,
Anton Kontunenb Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland;c Olfactomics Ltd, Tampere, FinlandView further author information
,
Jura Numminena Department of Otorhinolaryngology, Head and Neck Surgery, Tampere University Hospital, Tampere, FinlandORCID Iconhttps://orcid.org/0000-0003-4211-4244View further author information
ORCID Icon,
Niku Oksalab Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland;c Olfactomics Ltd, Tampere, Finland;d Vascular Centre, Tampere University Hospital, Tampere, FinlandView further author information
,
Markus Rautiainena Department of Otorhinolaryngology, Head and Neck Surgery, Tampere University Hospital, Tampere, Finland;b Faculty of Medicine and Health Technology, Tampere University, Tampere, FinlandView further author information
,
Antti Roinec Olfactomics Ltd, Tampere, Finland;e Department of Surgery, Tampere University Hospital, Hatanpää Hospital, Tampere, FinlandView further author information
&
Ilkka Kivekäsa Department of Otorhinolaryngology, Head and Neck Surgery, Tampere University Hospital, Tampere, Finland;b Faculty of Medicine and Health Technology, Tampere University, Tampere, FinlandView further author information
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Pages 524-531 | Received 09 May 2022, Accepted 15 Jun 2022, Published online: 05 Jul 2022

References

  • Hastan D, Fokkens WJ, Bachert C, et al. Chronic rhinosinusitis in Europe - An underestimated disease. A GA 2LEN study. Allergy Eur J Allergy Clin Immunol. 2011;66(9):1216–1223.
  • Fokkens WJ, Lund VJ, Hopkins C, et al. European position paper on rhinosinusitis and nasal polyps 2020. Rhin. 2020;58(1):1–464.
  • Orlandi RR, Kingdom TT, Smith TL, et al. International consensus statement on allergy and rhinology: rhinosinusitis 2021. Int Forum Allergy Rhinol. 2021;11(3):213–739.
  • Farraia MV, Cavaleiro Rufo J, Paciência I, et al. The electronic nose technology in clinical diagnosis. Porto Biomed J. 2019;4(4):e42.
  • Azim A, Barber C, Dennison P, et al. Exhaled volatile organic compounds in adult asthma: a systematic review. Eur Respir J. 2019;54(3):1900056.
  • Mohamed EI, Bruno E, Linder R, et al. A novel method for diagnosing chronic rhinosinusitis based on an electronic nose. Anal Otorrinolaringol Ibero-Am. 2003;30(5):447–57.
  • Thaler ER, Hanson CW. Use of an electronic nose to diagnose bacterial sinusitis. Am J Rhinol. 2006;20(2):170–172.
  • Broza YY, Braverman I, Haick H. Breath volatolomics for diagnosing chronic rhinosinusitis. Int J Nanomedicine. 2018;13:4661–4670.
  • Virtanen J, Hokkinen L, Karjalainen M, et al. In vitro detection of common rhinosinusitis bacteria by the eNose utilising differential mobility spectrometry. Eur Arch Otorhinolaryngol. 2018;275(9):2273–2279.
  • Koskinen A, Hammarén-Malmi S, Myller J, et al. Translation, cross-cultural adaptation, and validation of the sino-nasal outcome test (snot)-22 for Finnish patients. Eur Arch Otorhinolaryngol. 2021;278(2):405–410.
  • Virtanen J, Anttalainen A, Ormiskangas J, et al. Differentiation of aspirated nasal air from room air using analysis with a differential mobility spectrometry-based electronic nose: a proof-of-concept study. J Breath Res. 2022;16(1):016004.
  • American Thoracic Society, European Respiratory Society. ATS/ERS recommendations for standardized procedures for the online and offline measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide, 2005. Am J Respirat Critic Care Med. 2005;171(8):912–930.
  • Kumar L, Belaldavar BP, Bannur H. Influence of deviated nasal septum on nasal epithelium: an analysis. Head Neck Pathol. 2017;11(4):501–505.
  • Wang T, Pysanenko A, Dryahina K, et al. Analysis of breath, exhaled via the mouth and nose, and the air in the oral cavity. J Breath Res. 2008;2(3):037013.
  • Myles LT, Meyers TP, Robinson L. Atmospheric ammonia measurement with an ion mobility spectrometer. Atmos Environ. 2006;40(30):5745–5752.
  • Sielemann S, Baumbach JI, Schmidt H, et al. Detection of alcohols using UV-ion mobility spetrometers. Anal Chim Acta. 2001;431(2):293–301.
  • Bikov A, Hernadi M, Korosi BZ, et al. Expiratory flow rate, breath hold and anatomic dead space influence electronic nose ability to detect lung cancer. BMC Pulm Med. 2014;14(1):1–9.
  • Kischkel S, Miekisch W, Sawacki A, et al. Breath biomarkers for lung cancer detection and assessment of smoking related effects - confounding variables, influence of normalization and statistical algorithms. Clin Chim Acta. 2010;411(21–22):1637–1644.
  • Toma S, Hopkins C. Stratification of SNOT-22 scores into mild, moderate or severe and relationship with other subjective instruments. Rhinology. 2016;54(2):129–133.
  • Gregurić T, Trkulja V, Baudoin T, et al. Association between computed tomography findings and clinical symptoms in chronic rhinosinusitis with and without nasal polyps. Eur Arch Otorhinolaryngol. 2017;274(5):2165–2173.

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