Advanced search
Publication Cover
International Journal of Neuroscience Volume 113, 2003 - Issue 9
Submit an article Journal homepage
89
Views
78
CrossRef citations to date
0
Altmetric
Research Article

A BEHAVIORAL AND HISTOLOGICAL STUDY OF THE EFFECTS OF LONG-TERM EXPOSURE OF ADULT RATS TO ALUMINUM

ANDREI C. MIU Neuroscience Research Group, Department of Psychology, Babes-Bolyai University, Cluj-Napoca, Romania
,
CORINA E. ANDREESCU Neuroscience Research Group, Babes-Bolyai University, Cluj-Napoca, Romania; and Department of Physiology, School of Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania; and Neuroscience Institute, Erasmus University, Rotterdam, The Netherlands
,
RENATA VASIU Department of Pathological Anatomy, School of Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania
&
ADRIAN I. OLTEANU Neuroscience Research Group, Department of Psychology, Babes-Bolyai University, Cluj-Napoca, Romania; and Department of Physiology, School of Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania
Pages 1197-1211 | Published online: 07 Jul 2009

  • Aisen, P. S., & Davis, K. L. (1994). Inflammatory mechanisms in Alzheimer's disease: Implications for therapy. American Journal of Psychiatry, 151, 1105-1113.
  • Banks, W. A., Maness, L. M., Banks, M. R, & Kastin, A. J. (1996). Aluminum-sensitive degradation of amyloid ß-protein 1-40 by murine and human intracellular enzymes. Neurotoxicological Teratology, 18, 671-677
  • Bizzi, A., Crane, R. C., Autilio-Gambetti, L., & Gambetti, P. (1984). Aluminum effect on slow axonal transport: A novel impairment of neurofilament transport. Journal of Neuroscience, 4, 722-731.
  • Boegman, R. J., & Bates, L. A. (1984). Neurotoxicity of aluminum. Canadian Journal of Physiology and Pharmacology, 62, 1010-1014.
  • Bondy, S. C, & Truong, A. (1999). Potentiation of beta-folding of ß-amyloid peptide 25-35 by aluminum salts. Neuroscience Letters, 267, 25-28.
  • Buee, L., Hof, P. R., Bouras, C., Delacourte, A., Peri, D. P., Morrison, J. H., & Fillit, H. M. (1994). Pathological alterations of the cerebral microvasculature in Alzheimer's disease and related dementing disorders. Acta Neuropathologica, 87, 469-480.
  • Campbell, A., Smith, M. A., Sayre, L. M., Bondy, S. C., & Perry, G. (2001). Mechanisms by which metals promote events connected to neurodegenerative diseases. Brain Research Bulletin, 55, 125-132.
  • Capaldi, E. J., & Capaldi, E. D. (1972). Aversive learning situations: Apparatus and procedures. In R. D. Myers (Ed.), Methods in psychobiology (vol. 22, pp. 59-81). New York: Academic Press.
  • Casamenti, P., Prosperi, C., Scali, C., Giovanelli, L., Colivicchi, M. A., Faussone-Pellegrini, M. S., & Pepeu, G. (1999) Interleukin-1ß activates forebrain glial cells and increases nitric oxide production and cortical glutamate and GABA release in vivo: Implications for Alzheimer's disease. Neuroscience, 91, 831-842.
  • Chong, Y. H., & Suh, Y. H. (1995). Aggregation of amyloid precursor proteins by aluminum in vitro. Brain Research, 670, 137-141.
  • Cucarella, C., Montoliu, C., Hermenegildo, C., Saez, R., Manzo, L., Minana, M. N., & Felipo, V. (1998). Chronic exposure to aluminum impairs neuronal glutamate-nitric oxide-cyclic GMP pathway. Journal of Neurochemistry, 70, 1609-1614.
  • Denenberg, V. H. (1969). Open-field behavior in the rat: What does it mean? Annals of the New York Academy of Science, 159, 852-859.
  • Denenberg, V. H., Gartner, J., & Myers, M. (1975). Absolute measurement of open-field activity in mice. Physiology and Behavior, 15, 505-509.
  • Exley, C., Price, N. C, Kelly, S. M., & Birchall, J. D. (1993). An interaction of ß-amyloid with aluminum in vitro. FEBS Letters, 324, 293-295.
  • Flaten T. P., Glattre, E., Viste, A., & Søreide, O. (1991). Mortality from dementia among gastroduodenal ulcer patients. Journal of Epidemiology and Commununity Health, 45, 203-206.
  • Florence, A. L., Gauthier, A., Ponsar, C., van den Bosch de Aguilar, P., & Crichton, R. R. (1994). An experimental animal model of aluminum overload. Neurodegeneration, 3, 315-323.
  • Forster, D. P., Newens, A. J., Kay, D. W. K., & Edwardson, J. A. (1995). Risk factors in clinically diagnosed presenile dementia of Alzheimer type: A case-control study in northern England. Journal of Epidemiology and Commununity Health, 49, 253-258.
  • Gaytan-Garcia, S., Kim, H., & Strong, M. J. (1996). Spinal motor neuron neuroaxonal spheroids in chronic aluminum neurotoxicity contain phosphatase-resistant high molecular weight neurofilament. Toxicology, 108, 17-24.
  • Gulya, K., Rakonczay, Z., & Kasa, P. (1990). Cholinotoxic effects of aluminum in rat brain. Journal of Neurochemistry, 54, 1020-1026.
  • Herrnstein, R. J. (1969). Method and theory in the study of avoidance. Psychological Reviews, 76, 49-69.
  • Kawahara, M., Kalo, M., & Kuroda, Y. (2001). Effects of aluminum on the neurotoxicity of primary cultured neurons and on the aggregation of ß-amyloid protein. Brain Research Bulletin, 55, 211-217.
  • Kumar, S. (1998). Biphasic effect of aluminum on cholinergic enzyme of rat brain. Neuroscience Letters, 248, 121-123.
  • Letterier, J. F., Langui, D., Probst, A., & Ulrich, J. A. (1992). Molecular mechanism for the induction of neurofilament bundling by aluminum ions. Journal of Neurochemistry, 58, 2060-2070.
  • Mann, D. M. A., Marcyniuk, B., Yates, P. O., Neary, D., & Snowden, J. S. (1988). The progression of the pathological changes of Alzheimer's disease in frontal and temporal neocortex examined both at biopsy and at autopsy. Neuropathology and Applied Neurobiology, 14, 177-195.
  • Martyn, C. N., Osmond, C., Edwardson, J. A., Barker, D. J. P., Harris, E. C., & Lacey, R. F. (1989). Geographical relation between Alzheimer's disease and aluminum in drinking water. Lancet, 59-62.
  • Masliah, E., Terry, R. D., DeTeresa, R. M., & Hansen, L. A. (1989). Immunohistochemical quantification of the synapse-related protein synaptophysin in Alzheimer disease. Neuroscience Letters, 103, 234-239.
  • McLachlan, D. R., Bergeron, C., Smith, J. E., Boomer, D., & Rifat, S. L. (1996). Risk for neuropathologically-confirmed Alzheimer's disease and residual aluminum in municipal drinking water employing weighted residential histories. Neurology, 46, 401-405.
  • Miu, A. C, & Olteanu, A. I. (2003). Catalonia in Alzheimer's disease: The role of the amygdalo-hippocampal circuits. Behavoral amd Brain Sciences, 25, 5 (in press).
  • Miu, A. C., & Olteanu, A. L (2002). An ethological analysis of the open-field test: The effects of chlorpromazine and amphetamine. In A. Muresan and R. Orasan, (Eds.), Oxydative stress in physiological and pathological processes (pp. 94-96). Cluj-Napoca: Iuliu Hatieganu University of Medicine and Pharmacy Press.
  • Morris, R. (1984). Developments of a water-maze procedure for studying spatial learning in the rat. Journal of Neuroscience Methods, 11, 47-60.
  • Nieboer, E., Gibson, B. L., Oxman, A. D., & Kramer, J. R. (1995). Health effects of aluminum: A critical review with emphasis on aluminum in drinking water. Environmental Reviews, 3, 29-81.
  • Nixon, R. A., Clarke, J. F., Logvinenko, K. F., Tan, M. K., Hoult, M., & Grynspan, F. (1990). Aluminum inhibits calpain-mediated proteolysis and induces human neurofilament proteins to form protease-resistant high molecular wight complexes. Journal of Neurochemistry, 55, 1950-1959.
  • Pellegrino, L. J., Pellegrino, A. S., & Cushman, A. J. (1981). A Stereotaxic atlas of the rat brain. New York: Plenum Press.
  • Platt, B., Haas, H., & Büsselberg, D. (1994) Aluminum reduces glutamate-activated currents of rat hyppocampal neurones. NeuroReport, 5, 2329-2332.
  • Prapotnik, D., Smith, M. A., Richey, P. L., Vinters, H. V., & Perry, G. (1996). Filament heterogeneity within the dystrophic neuntes of senile plaques suggests blockade of fast axonal transport in Alzheimer's disease. Acta Neuropathologica, 91, 226-235.
  • Provan, S. D., & Yokel, R. A. (1992). Aluminum inhibits glutamate release from transverse rat hippocampal slices: Role of G proteins, Ca channels and protein kinase C. Neurotoxicology, 13, 413-420.
  • Rogers, M. A. M., & Simon, D. G. (1999). A preliminary study of dietary aluminum intake and risk of Alzheimer's disease. Age Ageing, 28, 205-209.
  • Saitoh, T., Masliah, E., Jin, L. W., Cole, G. M., Wieloch, T., & Shapiro, L P. (1991). Protein kinases and phosphorilation in neurologic disorders and cell death. Laboratory Investigations, 64, 596-616.
  • Scheff, S. W., DeKosky, S. T., & Price, D. A. (1990). Quantitative assessment of cortical synaptic density in Alzheimer's disease. Neurobiology of Aging, 11, 29-37.
  • Shea, T. B., & Husain, T. (1995) Inhibition of proteolysis enhances aluminum-induced perikaryal neurofilament accumulation but does not enhance tau accumulation. Molecular and Chemical Neuropathology, 26, 195-212.
  • Shin, R. W., Lee, V. M., & Trojanowski, J. Q. (1994). Aluminum modifies the properties of Alzheimer's disease PHF ? proteins in vitro and in vivo. Journal of Neuroscience, 14, 7221-7233.
  • Sternberger, N. H., Sternberger, L. A., & Ulrich, J. (1985). Aberrant neurofilament phosphorylation in Alzheimer disease. Proceedings of the National Academy of Science USA, 82, 4274-4276.
  • Struys-Ponsar, C, Kerkhofs, A., Gauthier, A., Sofflé, M., & van den Bosch de Aguilar, P. (1997). Effects of aluminum exposure on behavioral parameters in the rat. Pharmacology Biochemistry and Behavior, 56, 643-648.
  • Suárez-Fernández, M. B., Soldado, A. B., Sanz-Medel, A., Vega, J. A., Novelli, A., & Fernández-Sánchez, M. T. (1999) Aluminum-induced degeneration of astrocytes occurs via apoptosis and results in neuronal death. Brain Research, 835, 125-136.
  • Troncoso, J. C., Sternberger, N. H., Sternberger, L. A., Hoffman, P. N., & Price, D. L. (1986). Immunocytochemical studies of neurofilament antigens in the neurofibrillary pathology induced by aluminum. Brain Research, 364, 295-300.
  • Vamer, J. A., Jensen, K. P., Horvath, W., & Isaacson, R. L. (1998). Chronic administration of aluminum-fluoride or sodium-fluoride to rats in drinking water: Alterations in neuronal and cerebrovascular integrity. Brain Research, 784, 284-298.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.