41
Views
0
CrossRef citations to date
0
Altmetric
Original

INVESTIGATION OF NEUROPROTECTIVE EFFECT OF DEXAMETHASONE BY USING NITRIC OXIDE AND LEUKOCYTE LEVELS IN EXPERIMENTAL HEAD TRAUMA

, , , &
Pages 1719-1730 | Received 10 Sep 2007, Published online: 07 Jul 2009

REFERENCES

  • Clifton G. L. Contraversies in medical management of head injury. Clinical Neurosurgery 1988; 34: 587
  • Dearden N. M., Gibson J. S., McDowall D. G., Gibson R. M., Cameron M. M. Effect of high-dose dexamethasone on outcome from severe head injury. Journal of Neurosurgery 1986; 64: 81–88
  • Foda M. A., Marmarou A. A new model of diffuse brain injury in rats. Part II: Morphological characterization. Journal of Neurosurgery 1994; 80: 301–313
  • Hempen C., Weiss E., Hess C. F. Dexamethasone treatment in patients with brain metastases and primary brain tumors. Support Care Cancer 2002; 10: 322–328
  • Hortobagyi T., Hortobagyi S., Gorlach C., Harkany T., Benyo Z., Gorogh T., Nagel W., Wahl M. A novel brain trauma model in the mouse: Effects of dexamethasone treatment. Pflugers Archives 2000; 441: 409–415
  • Hu S., Zheng L., Chen B., Xie J., Yang C. The role of the leukocytes in pathogenesis of secondary brain injury. Hunan Yi Ke Da Xue Xue Bao 1999; 24: 56–58
  • Ikeda Y., Long D. The molecular basis of brain injury and brain edema. The role of oxygen free radicals. Neurosurgery 1999; 27: 1–11
  • Ludwig H. C. Dexamethasone in treatment of brain edema and intracranial hemorrhage. Internist 1998; 39: 531–532
  • Marshall F. L. The role of aggressive therapy for head injury; Does it matter? Clinical Neurosurgery 1988; 34: 549–559
  • Marshall L. F., Smith R. W., Shapiro H. M. The outcome with aggresive treatment in severe head injuries. Part II. Acute and chronic barbiturate administration in the management of head injury. Journal of Neurosurgery 1979; 50: 26–30
  • Meinig G., Deisenroth K. Dose-response relation for dexamethasone in cold lesion-induced brain edema in rats. Advances in Neurology 1990; 52: 295–300
  • Orihara Y., Ikematsu K., Tsuda R., Nakasono I. Induction of nitric oxide synthase by traumatic brain injury. Forensic Science Institutes 2001; 123: 142–149
  • Park C. O., Yi H. G. Apoptotic change and NOS activity in the experimental animal diffuse axonal injury model. Yonsei Medical Journal 2001; 42: 518–526
  • Rimpilainen J., Pokela M., Kiviluoma K., Anttila V., Vainionpaa V., Hirvonen J., Ohtonen P., Mennander A., Remes E., Juvonen T. Leukocyte filtration improves brain protection after a prolonged period of hypothermic circulotory arrest: A study in a chronic porcine model. Journal of Thoracic and Cardiovascular Surgery 2000; 120: 1131–1141
  • Rovlias A., Kotsou S. The blood leukocyte count and its prognostic significance in severe head injury. Surgical Neurology 2001; 55: 190–196
  • Sarin R., Murthy V. Medical decompressive therapy for primary and metastatic intracranial tumors. Lancet Neurology 2003; 2: 357–365
  • Stahr H. M. Analytical toxicology methods manual. Iowa State University Press, Ames 1977; 68–71
  • Wada K., Chatzipanteli K., Busto R., Dietrich W. D. Role of nitric oxide in traumatic brain injury in the rat. Journal of Neurotrauma 1999; 16: 203–212
  • Wang Z., Xu X., Wu X. Therapeutic effect of dexamethasone and mannitol on global brain ischemia-reperfusion injury in rats. Beijing Da Xue Xue Bao 2003; 35: 303–306
  • Yang Y., Huang W., Lu X. Early changes of endothelin, nitric oxide and arginine-vasopressin in patients with acute cerebral injury. Chinese Journal of Traumatology 2002; 5: 259–262
  • Zhang J., Snyder S. H. Nitric oxide in the nervous system. Annual Review of Pharmacology and Toxicology 1975; 35: 213–233

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.