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Original

COGNITIVE EFFECTS OF SHORT-TERM USE OF RALOXIFENE: A RANDOMIZED CLINICAL TRIAL

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Pages 1579-1590 | Received 28 Oct 2006, Published online: 07 Jul 2009

REFERENCES

  • Anderson G. L., Limacher M., Assaf A. R., Bassford T, Beresford Sx˙ Ax˙ A, Black H, Bonds D., Brunner R, Brzyski R, Caan B, Chlebowski R, Curb D, Gass M, Hays J, Heiss G, Hendrix S, Howard Bx˙ V, Hsia J, Hubbell A, Jackson R, Johnson Kx˙ C, Judd H, Kotchen Jx˙ M, Kuller L, LaCroix Ax˙ Z, Lane D, Langer Rx˙ D, Lasser N, Lewis Cx˙ E, Manson J, Margolis K, Ockene J, O'Sullivan Mx˙ J, Phillips L, Prentice Rx˙ L, Ritenbaugh C, Robbins J, Rossouw Jx˙ E, Sarto G, Stefanick Mx˙ L, Van Horn L, Wactawski-Wende J, Wallace R, Wassertheil-Smoller S. Women's Health Initiative Steering Committee. Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: The Women's Health Initiative randomized controlled trial. Journal of the American Medical Association 2004; 291: 1701–1712
  • Bryant H. U., Bales K. R., Paul S. M. Estrogen agonist effects of selective estrogen receptor modulators in ovariectomized rat brain (Abstract). Society for Neurosciences Abstracts 1997; 23: 2377
  • Clemens J. A., Bennett D. R., Black L. J., Jones Cx˙ D. Effects of a new antiestrogen, keoxifene, on growth of carcinogen-induced mammary tumors and on LH and prolactin levels. Life Sciences 1983; 32(25)2869–2875
  • Diaz Brinton R., Chen S., Montoya M., Hsieh D, Minaya J, Kim J, Chu Hx˙-P. The women's health initiative estrogen replacement therapy is neurotrophic and neuroprotective. Neurobiology of Aging 2000; 21(3)475–496
  • Drake E., Henderson V., Stanczyk F., McCleary Cx˙ A, Brown Wx˙ S, Smith Cx˙ A, Rizzo Ax˙ A, Murdock Gx˙A, Buckwalter Jx˙ G. Associations between circulating sex steroid hormones and cognition in normal elderly women. Neurology 2000; 54(3)599–603
  • Francucci C. M., Romagni P., Boscaro M. Raloxifene: Bone and cardiovascular effects. Journal of Endocrinology Investigation 2005; 28(10 Supplement)85–89
  • Gibbs R. B. Oestrogen and the cholinergic hypothesis: Implications for oestrogen replacement therapy in postmenopausal women. Novartis Foundation Symposium 2000; 230: 94–111
  • Grady D., Herrington D., Bittner V., Blumenthal R, Davidson M, Hlatky M, Hsia J, Hulley S, Herd A, Khan S, Newby Lx˙ K, Waters D, Vittinghoff E, Wenger N. Cardiovascular disease outcomes during 6.8 years of hormone therapy: Heart and Estrogen/progestin replacement study follow-up (HERS II). Journal of the American Medical Association 2002; 288(1)49–57
  • Henderson V. W., Watt L., Buckwalter J. G. Cognitive skills associated with estrogen replacement in women with Alzheimer's disease. Psychoneuroendocrinology 1996; 21(4)421–430
  • Hulley S., Furberg C., Barrett-Connor E., Cauley J, Grady D, Haskell W, Knopp R, Lowery M, Satterfield S, Schrott H, Vittinghoff E, Hunninghake D. Noncardiovascular disease outcomes during 6.8 years of hormone therapy: Heart and Estrogen/progestin replacement study follow-up (HERS II). Journal of the American Medical Association 2002; 288(1)58–66
  • Hulley S., Grady D., Bush T., Furberg C, Herrington D, Riggs B, Vittinghoff E. Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group. Journal of the American Medical Association 1998; 280(7)605–613
  • Kampen Dx˙ L, Sherwin Bx˙ B. Estrogen use and verbal memory in healthy postmenopausal women. Obstetrics and Gynecology 1994; 83(6)979–983
  • Leranth C., Roth R. H., Elswoth Jx˙Dx˙ F, Horvath Tx˙ L, Redmond Dx˙ Ex˙ Jr. Estrogen is essential for maintaining nigrostriatal dopamine neurons in primates: Implications for Parkinson's disease and memory. Journal of Neuroscience 2000; 20(23)8604–8609
  • Nickelsen T, Lufkin Ex˙ G, Riggs Bx˙ L, Cox Dx˙ A, Crook Tx˙ H. Raloxifene hydrochloride, a selective estrogen receptor modulator: Safety assessment of effects on cognitive function and mood in postmenopausal women. Psychoneuroendocrinology 1999; 24(1)115–128
  • Osterlund M. K., Halldin C., Hurd Y. L. Effects of chronic 17beta-estradiol treatment on the serotonin 5-HT(1A) receptor mRNA and binding levels in the rat brain. Synapse 2000; 35(1)39–44
  • Phillips S. M., Sherwin B. B. Effects of estrogen on memory function in surgically menopausal women. Psychoneuroendocrinology 1992; 17(5)485–495
  • Rapp S., Espeland M. A., Shumaker S. A., Henderson Vx˙ W, Brunner Rx˙ L, Manson Jx˙ E, Gass Mx˙ Lx˙ S, Stefanick Mx˙ L, Lane Dx˙ S, Hays J, Johnson Kx˙ C, Coker Lx˙ H., Dailey M, Bowen D. Effect of estrogen plus progestin on global cognitive function in postmenopausal women: Women's Health Initiative Memory Study; A Randomized Controlled Trial. Journal of the American Medical Association 2003; 289: 2663–2672
  • Robinson D, Friedman L, Marcus R, Tinklenberg J., Yesavage J. Estrogen replacement therapy and memory in older women. Journal of the American Geriatrics Society 1994; 42(9)919–922
  • Rossouw J. E., Anderson G. L., Prentice R. L., LaCroix Ax˙ Z, Kooperberg C, Stehanick Mx˙ L, Jackson Rx˙ D, Beresford Sx˙ A, Howard Bx˙ V, Johnson Kx˙ C, Kotchen Jx˙ M, Ockene J. Writing Group for the Women's Health Initiative Investigators Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the Women's Health Initiative randomized controlled trial. Journal of the American Medical Association 2002; 288(3)321–333
  • Sherwin B. B. Estrogen and/or androgen replacement therapy and cognitive functioning in surgically menopausal women. Psychoneuroendocrinology 1988; 13(4)345–357
  • Shughrue P. J., Lane M. V., Merchenthaler I. Regulation of progesterone receptor messenger ribonucleic acid in the rat medial preoptic nucleus by estrogenic and antiestrogenic compounds: An in situ hybridization study. Endocrinology 1997; 138(12)5476–5484
  • Shumaker S. A., Legault C., Kuller L., Rapp Sx˙ R, Thaell L, Lane Dx˙ S, Fillit H, Stefanick Mx˙ L, Hendrix Sx˙ L, Lewis Cx˙ E, Masaki K, Coker Lx˙ H. Conjugated equine estrogens and incidence of probable dementia and mild cognitive impairment in postmenopausal women: Women's Health Initiative Memory Study. Journal of the American Medical Association 2004; 291(24)2947–2958
  • Shumaker S. A., Legault C., Rapp S. R. Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women. The Women's Health Initiative Memory Study: A randomized controlled trial. Journal of the American Medical Association 2003; 289: 2651–2662
  • Wassertheil-Smoller S, Hendrix S.L, Limacher M, Heiss G, Kooperberg C, Baird A, Kotchen T, Curb Jx˙ D, Black H, Rossouw Lx˙ E, Aragaki A, Safford M, Stein E, Laowattana S, Mysiw Wx˙ J. Effect of estrogen plus progestin on stroke in postmenopausal women: The Women's Health Initiative: A randomized trial. Journal of the American Medical Association 2003; 28(20)2673–2684
  • Yaffe K, Krueger K, Sarkar S, Grady D, Barrett-Connor E, Cox Dx˙ A, Nickelsen T. Cognitive function in postmenopausal women treated with raloxifene. New England Journal of Medicine 2001; 344(16)1207–1213

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