Adolescent and Adult Male Spontaneous Hyperactive Rats (SHR) Respond Differently to Acute and Chronic Methylphenidate (Ritalin)

REFERENCES

• Adriani W., Chiarotti F., Laviola G. Elevated novelty seeking and peculiar d-amphetamine sensitization in periadolescent mice compared with adult mice. Behavioral Neuroscience 1998; 112: 1152–1166
   PubMed Web of Science ®Google Scholar
• Anderson S. L., Arvanitogiannis A., Pliakas A. M., LeBlanc C., Carlezon W. A., Jr. Altered responsiveness to cocaine in rats exposed to methylphenidate during development. Nature Neuroscience 2002; 5(1)13–14
   PubMed Web of Science ®Google Scholar
• Brandon C. L., Marinelli M., Baker L. K., White F. J. Enhanced reactivity and vulnerability to cocaine following methylphenidate treatment in adolescent rats. Neuropsychopharmacology 2001; 25: 651–661
   PubMed Web of Science ®Google Scholar
• Browman K. E., Badiani A., Robinson T. E. The influence of environment on the induction of sensitization to the psychomotor activating effects of intravenous cocaine in rats is dose-dependent. Psychopharmacaology (Berl) 1998; 137(1)90–98
   PubMed Web of Science ®Google Scholar
• Caihol S., Mormede P. Strain and sex differences in the locomotor response and behavioral sensitization to cocaine in hyperactive rats. Brain Research 1999; 842: 200–205
   PubMed Web of Science ®Google Scholar
• Crawford C. A., McDougall S. A., Meier T. L., Collins R. L., Watson J. B. Repeated methylphenidate treatment induces behavioral sensitization and decreases protein kinase A and dopamine-stimulated adenylyl cyclase activity in the dorsal striatum. Psychopharmacology 1998; 136: 24–33
   PubMed Web of Science ®Google Scholar
• Crombag H. S., Badiani A., Chan J. C., Dell'Orco J., Dineen S. P., Robinson T. E. Psychomotor sensitization to amphetamine can be dissociated from its effects on acute drug responsiveness and on conditioning responding. Neuropsychopharmacology 2001; 24: 680–690
   PubMed Web of Science ®Google Scholar
• Drug Enforcement Administration, Office of Diversion Control, Methylphenidate Review. Eight Factor Analysis, et al. Drug Enforcement Administration, Washington, DC 2000
   Google Scholar
• Eichlseder W. Ten years of experience with 1000 hyperactive children in private practice. Pediatrics 1985; 76: 176–181
   PubMed Web of Science ®Google Scholar
• Fessler R. G., Sturgeon R. D., Meltzer H. F. Effects of phencyclidine and methylphenidate on D-amphetamine-induced behavior in reserpine pretreated rats. Pharmacology Biochemistry, and Behavior 1980; 13: 835–842
   PubMed Web of Science ®Google Scholar
• Gainetdinov R. R., Jones S. R., Fumagalli F., Wightman R. M., Caron M. G. Re-evaluation of the role of the dopamine transporter in dopamine system homeostasis. Brain Research Reviews 1998; 26: 148–153
   PubMedGoogle Scholar
• Gatley S. J., Volkow N. D., Gifford A. N., Fowler J. S., Dewey S. L., Ding Y. S., et al. Dopamine-transporter occupancy after intravenous doses of cocaine and methylphenidate in mice and humans. Psychopharmacology 1999; 146: 93–100
   PubMed Web of Science ®Google Scholar
• Gaytan O., Ghelani D., Martin S., Swann A., Dafny N. Dose response characteristics of methylphenidate on different indices of rats’ locomotor activity at the beginning of the dark cycle. Brain Research 1996; 727: 13–21
   PubMed Web of Science ®Google Scholar
• Gaytan O., al-Rahim S., Swann A., Dafny N. Sensitization to locomotor effects of methylphenidate in the rat. Life Science 1997a; 61: PL101–PL107
   PubMed Web of Science ®Google Scholar
• Gaytan O., Ghelani D., Martin S., Swann A., Dafny N. Methylphenidate: Diurnal effects on locomotor and stereotypic behavior in the rat. Brain Research 1997b; 777: 1–12
   PubMed Web of Science ®Google Scholar
• Gaytan O., Yang P., Swann A., Dafny N. Diurnal differences in sensitization to methylphenidate. Brain Research 2000; 864: 24–39
   PubMed Web of Science ®Google Scholar
• Gerasimov M. R., Franceschi M., Volkow N. D., Gifford A., Gatley S. J., Marsteller D., et al. Comparison between intraperitoneal and oral methylphenidate administration: A microdialysis and locomotor activity study. The Journal of Pharmacology and Experimental Therapeutics 2000; 295: 51–57
   PubMed Web of Science ®Google Scholar
• Gessa G. L., Pani L., Serra G., Fratta W. Animal models of mania. Advances in Biochemical Psychopharmacology 1995; 49: 43–66
   PubMedGoogle Scholar
• Goldman L. S., Genel M., Bezman R. J., Slanetz P. J. Diagnosis and treatment of attention deficit/hyperactivity disorder in children and adolescents. Journal of the American Medical Association 1998; 279: 1100–1107
   PubMed Web of Science ®Google Scholar
• Hooks M. S., Jones G. H., Smith A. D., Neill D. B., Justice J. B. Individual differences in locomotor activity and sensitization. Pharmacology, Biochemistry, and Behavior 1991; 38: 467–470
   PubMed Web of Science ®Google Scholar
• Kalivas P. W. Neural basis of behavioral sensitization to cocaine. The Neurobiology of Cocaine., R. P. Hammer. CRC Press, Boca Raton, FL 1995; 81–98
   Google Scholar
• Kalivas P. W., Pierce R. C., Cornish J., Sorg B. A. A role of sensitization in craving and relapse in cocaine addiction. Journal of Psychopharmacology 1998; 12: 49–53
   PubMed Web of Science ®Google Scholar
• Kalivas P. W., Stewart J. Dopamine transmission in the initiation and expression of drug- and stress-induced sensitization of motor activity. Brain Research Reviews 1991; 16: 233–244
   Google Scholar
• Karande S. Attention deficit and hyperactivity disorder: A review for family physicians. Indian Journal of Medical Science 2005; 59: 547–556
   Google Scholar
• Karler R., Calder L. D., Bedingfield J. B. Cocaine behavioral sensitization and the excitatory amino acids. Psychopharmacology 1994; 115: 305–310
   PubMed Web of Science ®Google Scholar
• Karler R., Chaudhry I. A., Calder L. D., Turkanis S. A. Amphetamine behavioral sensitization and then excitatory amino acids. Brain Research 1990; 537: 76–82
   PubMed Web of Science ®Google Scholar
• King J. A., Kelley T. A., Deville Y. Adult levels of testosterone alter catecholamine innervation in an animal model of attention deficit hyperactivity disorder. Neuropsychobiology 2000; 42: 163–168
   PubMed Web of Science ®Google Scholar
• Kollins S. H., MacDonald E. K., Rush C. R. Assessing the abuse potential of methylphenidate in non-human and human subjects A review. Pharmacology, Biochemistry, and Behavior 2001; 68: 611–627
   PubMed Web of Science ®Google Scholar
• Kuczenski R., Segal D. S. Sensitization of amphetamine-induced stereotyped behaviors during the acute response. The Journal of Pharmacology and Experimental Therapeutics 1999; 288: 699–709
   PubMed Web of Science ®Google Scholar
• Kuczenski R., Segal D. S. Locomoter effects of acute and repeated threshold doses of amphetamine and methylphenidate: Relative roles of dopamine and norepinephrine. The Journal of Pharmacology and Experimental Therapeutics 2001; 296: 876–883
   PubMed Web of Science ®Google Scholar
• Laviola G., Wood R. D., Kuhn C., Francis R., Spear L. P. Cocaine sensitization in periadolescent and adult rats. The Journal of Pharmacology and Experimental Therapeutics 1995; 275(9)345–357
   PubMed Web of Science ®Google Scholar
• Liebermann J. A., Sheitman B. B., Kinon B. J. Neurochemical sensitization in the pathophysiology of schizophrenia: Deficits and dysfunction in normal regulation and plasticity. Neuropsychopharmacology 1997; 17: 205–229
   PubMed Web of Science ®Google Scholar
• Newcorn J. H. A glimpse into key issues in ADHD. CNS Spectrum 2000; 5: 25
   PubMedGoogle Scholar
• Patrick K. S., Ellington K. R., Breese G. R. Distribution of methylphenidate and p-hydroxymethylphenidate in rats. The Journal of Pharmacology and Experimental Therapeutics 1984; 231: 61–65
   PubMed Web of Science ®Google Scholar
• Pauls D. L. Genetic factors in the expression of attention-deficit hyperactivity disorder. Journal of Child and Adolescent Psychopharmacology 1991; 1: 353–360
   PubMedGoogle Scholar
• Pelham W. E., Gnagy E. M., Burrows-Maclean L., Williams A., Fabiano G. A., Morrisey S. M., et al. Once-a-day concerta methylphenidate versus three times-daily methylphenidate in laboratory and natural settings. Pediatrics 2001; 107: 1–15
   PubMed Web of Science ®Google Scholar
• Phillips. Behavior genetics of drug sensitization. Critical Reviews in Neurobiology 1997; 11: 21–33
   PubMedGoogle Scholar
• Pierce C. R., Kalivas P. W. A circuitry model of the expression of behavioral sensitization to amphetamine-like psychostimulants. Brain Research Reviews 1997; 25: 192–216
   PubMed Web of Science ®Google Scholar
• Post R. M., Weiss S. R., Pert A. Cocaine-induced behavioral sensitization and kindling: Implications for the emergence of psychopathology and seizures. Annals of the New York Academy of Sciences 1988; 537: 292–308
   PubMed Web of Science ®Google Scholar
• Robinson T. E., Becker J. B. Enduring changes in brain and behavior produced by chronic emphetamine psychosis. Brain Research 1986; 396: 157–198
   PubMed Web of Science ®Google Scholar
• Robinson T. E., Berridge K. C. The neural basis of drug craving: An incentive-sensitization theory of addiction. Brain Research 1993; 18: 247–291
   Web of Science ®Google Scholar
• Safer D. J., Zito J. M., Fine E. M. Increased methylphenidate usage for attention deficit disorder in the 1990s. Pediatrics 1996; 98: 1084–1088
   PubMed Web of Science ®Google Scholar
• Sagvolden T. Behavioral validation of the spontaneously hypertensive rat (SHR) as an animal model of attention-deficit hyperactivity disorder (ADHD). Neuroscience and Biobehavioral Reviews 2000; 24: 31–39
   PubMed Web of Science ®Google Scholar
• Sagvolden T., Metzger M. A., Schiorbeck H. K., Rugland A. L., Spinnangr I., Sagvolden G. The spontaneously hypertensive rat (SHR) as an animal model of childhood hyperactivity (ADHD): Changed reactivity to reinforcers and to psychomotor stimulants. Behavioral and Neural Biology 1992; 58: 103–112
   PubMedGoogle Scholar
• Sagvolden T., Sergeant J. A Attention deficit/hyperactivity disorder-from brain dysfunctions to behavior. Behavioural Brain Research 1998; 94: 1–10
   PubMed Web of Science ®Google Scholar
• Sax K. W., Strakowski S. M. Enhanced behavioral response to repeated D-amphetamine and personality traits in humans. Biological Psychiatry 1998; 44: 1192–1195
   PubMed Web of Science ®Google Scholar
• Scheel-Kruger J. Comparative studies of various amphetamine analogues demonstrating different interactions with the metabolism of the catecholamines in the brain. European Journal of Pharmacology 1971; 14: 47–59
   PubMed Web of Science ®Google Scholar
• Segal A. J., Mandell D. S. Long-term administration of D-amphetamine: Progressive augmentation of motor activity and stereotypy. Pharmacology, Biochemisty, and Behavior 1982; 2(1974)249–255
   Google Scholar
• Shuster L., Hudson J., Anton M., Righi D. Sensitization of mice to methylphenidate. Psychopharmacology 1982; 77: 31–36
   PubMed Web of Science ®Google Scholar
• Solanto M. V. Clinical psychopharmacology of ADHD: Implications for animal models. Neuroscience and Biobehavioral Reviews 2000; 24: 27–30
   PubMed Web of Science ®Google Scholar
• Spear L. P., Brake S. C. Periadolescence: Age-dependent behavior and psychopharmacological responsivity in rats. Developmental Psychobiology 1983; 16(2)83–109
   PubMed Web of Science ®Google Scholar
• Swanson J., Gupta S., Guinta D., Flynn D., Agler D., Lerner M., et al. Acute tolerance to methylphenidate in the treatment of attention deficit hyperactivity disorder in children. Clinical Pharmacology and Therapeutics 1999; 66: 295–305
   PubMed Web of Science ®Google Scholar
• Torres-Reveron A., Dow-Edwards D. L. Repeated administration of methylphenidate in young, adolescent, and mature rats affects the response to cocaine later in adulthood. Psychopharmacology (Berl) 2005; 181(1)38–47
   PubMed Web of Science ®Google Scholar
• White S. R., Yadao C. M. Characterization of methylphenidate exposures reported to a regional poison control center. Archives of Pediatrics and Adolescent Medicine 2000; 154: 1199–1203
   PubMed Web of Science ®Google Scholar
• Wolf M. E. The role of excitatory amino acids in behavioral sensitization to psychomotor stimulants. Progress in Neurobiology 1998; 54: 679–720
   PubMed Web of Science ®Google Scholar
• Wultz B., Sagvolden T., Moser E. I., Moser M. B. The spontaneously hypertensive rat as an animal model of ADHD: Effects of methylphenidate on exploratory behavior. Behavioral and Neural Biology 1990; 26: 676–686
   Google Scholar
• Yang P., Amini B., Swann A. C., Dafny N. Strain differences in the behavioral responses of male rats to chronically administered methylphenidate. Brain Research 2003; 971: 139–152
   PubMed Web of Science ®Google Scholar
• Yang P., Beasley A., Swann A. C., Dafny N. Valproate modulates the expression of methylphenidate (Ritalin) sensitization. Brain Research 2000; 874: 216–220
   PubMed Web of Science ®Google Scholar
• Yang P., Swann A. C., Dafny N. Chronic administration of methylphenidate produces neurophysiological and behavioral sensitization. Brain Research 2007; 1145: 66–80
   PubMed Web of Science ®Google Scholar