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Original Article

Low T3 levels as a predictor marker predict the prognosis of patients with acute ischemic stroke

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Pages 559-566 | Received 11 May 2016, Accepted 07 Jul 2016, Published online: 27 Jul 2016

References

  • Ryu WS, Park JB, Ko SB, et al. Diastolic dysfunction and outcome in acute ischemic stroke. Cerebrovasc Dis 2016;41(3–4):148–55.
  • Bunevicius A, Kazlauskas H, Raskauskiene N, et al. Ischemic stroke functional outcomes are independently associated with C-reactive protein concentrations and cognitive outcomes with triiodothyronine concentrations: a pilot study. Endocrine 2014;45(2):213–20.
  • Fontana M, Passino C, Poletti R, et al. Low triiodothyronine and exercise capacity in heart failure. Int J Cardiol 2012;154(2):153–7.
  • Warner MH, Beckett GJ. Mechanisms behind the non-thyroidal illness syndrome: an update. J Endocrinol 2010;205(1):1–13.
  • Akhoundi FH, Ghorbani A, Soltani A, et al. Favorable functional outcomes in acute ischemic stroke patients with subclinical hypothyroidism. Neurology 2011;77(4):349–54.
  • Samuels MA. The brain-heart connection. Circulation 2007;116(1):77–84.
  • Zi WJ, Shuai J. Cortisol as a prognostic marker of short-term outcome in Chinese patients with acute ischemic stroke. PLoS One 2013;8(9):e72758.
  • Brott T, Marler JR, Olinger CP, et al. Measurements of acute cerebral infarction: lesion size by computed tomography. Stroke 1989;20(7):871–5.
  • Brott T, Adams HP, Jr., Olinger CP, et al. Measurements of acute cerebral infarction: a clinical examination scale. Stroke 1989;20(7):864–70.
  • Martin-Schild S, Albright KC, Tanksley J, et al. Zero on the NIHSS does not equal the absence of stroke. Ann Emerg Med 2011;57(1):42–5.
  • Huang S, Huang GQ, Zhu GQ, et al. Establishment and validation of SSCLIP scoring system to estimate survival in hepatocellular carcinoma patients who received curative liver resection. PLoS One 2015;10(6):e0129000.
  • Yang X, Ren W, Zu H, et al. Evaluate the serum cortisol in patients with intracerebral hemorrhage. Clin Neurol Neurosurg 2014;123:127–30.
  • Ren W, Gu Y, Zhu L, et al. The effect of cigarette smoking on vitamin D level and depression in male patients with acute ischemic stroke. Compr Psychiatry 2016;65:9–14.
  • van Swieten JC, Koudstaal PJ, Visser MC, et al. Interobserver agreement for the assessment of handicap in stroke patients. Stroke 1988;19(5):604–7.
  • Hacke W, Kaste M, Fieschi C, et al. Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke. The European Cooperative Acute Stroke Study (ECASS). J Am Med Assoc 1995;274(13):1017–25.
  • Alevizaki M, Synetou M, Xynos K, et al. Low triiodothyronine: a strong predictor of outcome in acute stroke patients. Eur J Clin Invest 2007;37(8):651–7.
  • Go AS, Mozaffarian D, Roger VL, et al. Heart disease and stroke statistics–2013 update: a report from the American Heart Association. Circulation 2013;127(1):e6–e245.
  • Bunevicius A, Iervasi G, Bunevicius R. Neuroprotective actions of thyroid hormones and low-T3 syndrome as a biomarker in acute cerebrovascular disorders. Expert Rev Neurother 2015;15(3):315–26.
  • Iervasi G, Pingitore A, Landi P, et al. Low-T3 syndrome: a strong prognostic predictor of death in patients with heart disease. Circulation 2003;107(5):708–13.
  • Scoscia E, Baglioni S, Eslami A, et al. Low triiodothyronine (T3) state: a predictor of outcome in respiratory failure? Results of a clinical pilot study. Eur J Endocrinol 2004;151(5):557–60.
  • Bunevicius A, Deltuva V, Tamasauskas S, et al. Low triiodothyronine syndrome as a predictor of poor outcomes in patients undergoing brain tumor surgery: a pilot study: clinical article. J Neurosurg 2013;118(6):1279–87.
  • Chopra IJ. Clinical review 86: euthyroid sick syndrome: is it a misnomer? J Clin Endocrinol Metab 1997;82(2):329–34.
  • De Groot LJ. Dangerous dogmas in medicine: the nonthyroidal illness syndrome. J Clin Endocrinol Metab 1999;84(1):151–64.
  • McIver B, Gorman CA. Euthyroid sick syndrome: an overview. Thyroid 1997;7(1):125–32.
  • Coceani M, Iervasi G, Pingitore A, et al. Thyroid hormone and coronary artery disease: from clinical correlations to prognostic implications. Clin Cardiol 2009;32(7):380–5.
  • Fassbender K, Schmidt R, Mossner R, et al. Pattern of activation of the hypothalamic-pituitary-adrenal axis in acute stroke. Relation to acute confusional state, extent of brain damage, and clinical outcome. Stroke 1994;25(6):1105–8.
  • Johansson A, Olsson T, Carlberg B, et al. Hypercortisolism after stroke–partly cytokine-mediated? J Neurol Sci 1997;147(1):43–7.
  • Marklund N, Peltonen M, Nilsson TK, et al. Low and high circulating cortisol levels predict mortality and cognitive dysfunction early after stroke. J Intern Med 2004;256(1):15–21.
  • Chrousos GP. The hypothalamic-pituitary-adrenal axis and immune-mediated inflammation. N Engl J Med 1995;332(20):1351–62.
  • Mendes-de-Aguiar CB, Alchini R, Decker H, et al. Thyroid hormone increases astrocytic glutamate uptake and protects astrocytes and neurons against glutamate toxicity. J Neurosci Res 2008;86(14):3117–25.
  • Schlenker EH, Hora M, Liu Y, et al. Effects of thyroidectomy, T4, and DITPA replacement on brain blood vessel density in adult rats. Am J Physiol Regul Integr Comp Physiol 2008;294(5):R1504–9.
  • Roeder LM, Hopkins IB, Kaiser JR, et al. Thyroid hormone action on glucose transporter activity in astrocytes. Biochem Biophys Res Commun 1988;156(1):275–81.
  • Westerholz S, de Lima AD, Voigt T. Regulation of early spontaneous network activity and GABAergic neurons development by thyroid hormone. Neuroscience 2010;168(2):573–89.
  • Alevizaki M, Synetou M, Xynos K, et al. Hypothyroidism as a protective factor in acute stroke patients. Clin Endocrinol (Oxf) 2006;65(3):369–72.
  • Utiger RD. Altered thyroid function in nonthyroidal illness and surgery. To treat or not to treat? N Engl J Med 1995;333(23):1562–3.
  • Stathatos N, Levetan C, Burman KD, et al. The controversy of the treatment of critically ill patients with thyroid hormone. Best Pract Res Clin Endocrinol Metab 2001;15(4):465–78.
  • De Groot LJ. Non-thyroidal illness syndrome is a manifestation of hypothalamic-pituitary dysfunction, and in view of current evidence, should be treated with appropriate replacement therapies. Crit Care Clin 2006;22(1):57–86.
  • Brent GA, Hershman JM. Thyroxine therapy in patients with severe nonthyroidal illnesses and low serum thyroxine concentration. J Clin Endocrinol Metab 1986;63(1):1–8.
  • Byerley LO, Heber D. Metabolic effects of triiodothyronine replacement during fasting in obese subjects. J Clin Endocrinol Metab 1996;81(3):968–76.
  • Zhang Y, Meyer MA. Clinical analysis on alteration of thyroid hormones in the serum of patients with acute ischemic stroke. Stroke Res Treat 2010;290678. doi:10.4061/2010/290678

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