The behavioral deficits and cognitive impairment are correlated with decreased IGF-II and ERK in depressed mice induced by chronic unpredictable stress

References

• Detanico BC, Piato ÂL, Freitas JJ, et al. Antidepressant-like effects of melatonin in the mouse chronic mild stress model. Eur J Pharmacol 2009;607(1–3):121–5.
   PubMed Web of Science ®Google Scholar
• Lupien SJ, McEwen BS, Gunnar MR, Heim C. Effects of stress throughout the lifespan on the brain, behaviour and cognition. Nat Rev Neurosci 2009;10(6):434–45.
   PubMed Web of Science ®Google Scholar
• Buwalda B, Kole MH, Veenema AH, et al. Long-term effects of social stress on brain and behavior: a focus on hippocampal functioning. Neurosci Biobehav Rev 2005;29(1):83–97.
   PubMed Web of Science ®Google Scholar
• Arnsten AF. Stress signalling pathways that impair prefrontal cortex structure and function. Nature 2009;10:410–22.
   Web of Science ®Google Scholar
• Russo VC, Gluckman PD, Feldman EL, et al. The insulin-like growth factor system and its pleiotropic functions in brain. Endocr Rev 2005;26(7):916–43.
   PubMed Web of Science ®Google Scholar
• Hawkes C, Kar S. The insulin-like growth factor-II/mannose-6-phosphate receptor: structure, distribution and function in the central nervous system. Brain Res Brain Res Rev 2004;44(2–3):117–40.
   PubMedGoogle Scholar
• Chen DY, Stern SA, Garcia-Osta A, Saunier-Rebori B, et al. A critical role for IGF-II in memory consolidation and enhancement. Nature 2011;469(7331):491–8.
   PubMed Web of Science ®Google Scholar
• Agis-Balboa RC, Arcos-Diaz D, Wittnam J, et al. A hippocampal insulin-growth factor 2 pathway regulates the extinction of fear memories. EMBO J 2011;30:4071–83.
   PubMed Web of Science ®Google Scholar
• Mebratu Y, Tesfaigzi Y. How ERK1/2 activation controls cell proliferation and cell death: is subcellular localization the answer? Cell Cycle 2009;8(8):1168–75.
   PubMed Web of Science ®Google Scholar
• Choi YS, Cho HY, Hoyt KR, et al. IGF-1 receptor-mediated ERK/MAPK signaling couples status epilepticus to progenitor cell proliferation in the subgranular layer of the dentate gyrus. Glia 2008;56(7):791–800.
   PubMed Web of Science ®Google Scholar
• Willner P, Towell A, Sampson D, et al. Reduction of sucrose preference by chronic unpredictable mild stress, and its restoration by a tricyclic antidepressant. Psychopharmacology (Berl) 1987;93(3):358–64.
   PubMed Web of Science ®Google Scholar
• Park SH, Sim YB, Han PL, et al. Antidepressant-like effect of chlorogenic acid isolated from Artemisia capillaris Thunb. Anim Cells Syst 2010;4(4):253–9.
   Web of Science ®Google Scholar
• Song L, Che W, Min-Wei W, et al. Impairment of the spatial learning and memory induced by learned helplessness and chronic mild stress. Pharmacol Biochem Behav 2006;83(2):186–93.
   PubMed Web of Science ®Google Scholar
• Jeon BT, Shin HJ, Kim JB, et al. Adiponectin protects hippocampal neurons against kainic acid-induced excitotoxicity. Brain Res Rev 2009;61(2):81–8.
   PubMedGoogle Scholar
• Tianzhu Z, Shihai Y, Juan D. Antidepressant-like effects of cordycepin in a mice model of chronic unpredictable mild stress. Evid Based Complement Alternat Med 2014;2014:438506.
   PubMed Web of Science ®Google Scholar
• Hill MN, Hunter RG, McEwen BS. Chronic stress differentially regulates cannabinoid CB1 receptor binding in distinct hippocampal subfields. Europ J Pharmacol 2009;614(1–3):66–9.
   PubMed Web of Science ®Google Scholar
• Lee TT, Hill MN. Age of stress exposure modulates the immediate and sustained effects of repeated stress on corticolimbic cannabinoid CB₁ receptor binding in male rats. Neurosci 2013;26 and 249:106–14.
   Web of Science ®Google Scholar
• Ouchi Y, Banno Y, Shimizu Y, et al. Reduced adult hippocampal neurogenesis and working memory deficits in the Dgcr8deficient mouse model of 22q11.2 deletion-associated schizophrenia can be rescued by IGF2. J Neurosci 2013;33(22):9408–19.
   PubMed Web of Science ®Google Scholar
• Stern SA, Kohtz AS, Gabriella P, et al. Enhancement of memories by systemic administration of insulin-like growth factor II. Neuropsycho 2014;39(9):2179–90.
   Google Scholar
• Luo YW, Xu Y, Cao WY, et al. Insulin-like growth factor 2 mitigates depressive behavior in a rat model of chronic stress. Neuropharmacology 2015;89:318–24.
   PubMed Web of Science ®Google Scholar
• Rivera EJ, Goldin A, Fulmer N, et al. Insulin and insulin-like growth factor expression and function deteriorate with progression of Alzheimer's disease: link to brain reductions in acetylcholine. J Alzheimers Dis 2005;8(3):247–68.
   PubMed Web of Science ®Google Scholar
• Mellott TJ, Pender SM, Burke RM, et al. IGF2 ameliorates amyloidosis, increases cholinergic marker expression and raises BMP9 and neurotrophin levels in the hippocampus of the APPswePS1dE9 Alzheimer's disease model mice. Plos One 2014;9(4):e94287.
   PubMed Web of Science ®Google Scholar
• Burke RM, Norman TA, Hayda TF, et al. BMP9 ameliorates amyloidosis and the cholinergic defect in a mouse model of Alzheimer's disease. Proc Natl Acad Sci USA 2013;110(48):19567.
   PubMed Web of Science ®Google Scholar
• Alberini CM, Chen DY. Memory enhancement: consolidation, reconsolidation and insulin-like growth factor 2. Trends Neurosci 2012;35(5):274–83.
   PubMed Web of Science ®Google Scholar
• Fernandez AM, Torres-Aleman I. The many faces of insulin-like peptide signalling in the brain. Nat Rev Neurosci 2012;13(4):225–39.
   PubMed Web of Science ®Google Scholar
• Peng S, Zhang Y, Zhang J, et al. ERK in learning and memory: a review of recent research. Int J Mol Sci 2010;11(1):222–32.
   PubMed Web of Science ®Google Scholar
• Gourley SL, Wu FJ, Kiraly DD, et al. Regionally specific regulation of ERK MAP kinase in a model of antidepressant-sensitive chronic depression. Biol Psychiatry 2008;63(4):353–9.
   PubMed Web of Science ®Google Scholar
• Meller E, Shen C, Nikolao TA, et al. Region specific effects of acute and repeated restraint stress on the phosphorylation of mitogen activated protein kinases. Brain Res 2003;979(1–2):57–64.
   PubMed Web of Science ®Google Scholar
• First M, Gil-Ad I, Taler M, et al. The effects of fluoxetine treatment in a chronic mild stress rat model on depression-related behavior, brain neurotrophins and ERK expression. J Mol Neurosci 2011;45(2):246–55.
   PubMed Web of Science ®Google Scholar
• Qi X, Lin W, Li J, et al. The depressive-like behaviors are correlated with decreased phosphorylation of mitogen-activated protein kinases in rat brain following chronic forced swim stress. Behav Brain Res 2006;175(2):233–40.
   PubMed Web of Science ®Google Scholar