Pindolol potentiates the antidepressant effect of venlafaxine by inhibiting 5-HT1A receptor in DRN neurons of mice

References

• Twarkowski H, Hagena H, Manahan-Vaughan D. The 5-hydroxytryptamine4 receptor enables differentiation of informational content and encoding in the hippocampus. Hippocampus. 2016;26(7):875–891.
   PubMed Web of Science ®Google Scholar
• Dedic N, Walser SM, Deussing JM. Mouse models of depression. In: Uehara T, editor. Psychiatric disorders – Trends and developments. InTech; 2011. p. 185–222. ISBN: 978-953-307-745-1, Available from: http://www.intechopen.com/books/psychiatric-disorders-trends-and-developments/mouse-models-of-depression.
   Google Scholar
• Mathers CD, Loncar D. Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med. 2006;3(11):e442.
   PubMed Web of Science ®Google Scholar
• Jans LAW, Riedel WJ, Markus CR, et al. Serotonergic vulnerability and depression: assumptions, experimental evidence and implications. Mol Psychiatry. 2007;12(6):522–543.
   PubMed Web of Science ®Google Scholar
• Albert PR, François BL, Millar AM. Transcriptional dysregulation of 5-HT1A autoreceptors in mental illness. Mol Brain. 2011;4(1):21.
   PubMed Web of Science ®Google Scholar
• Mendez-David I, David DJ, Darcet F, et al. Rapid anxiolytic effects of a 5-HT4 receptor agonist are mediated by a neurogenesis-independent mechanism. Neuropsychopharmacology. 2014;39(6):1366–1378.
   PubMed Web of Science ®Google Scholar
• Hjorth S. Serotonin 5-HT1A autoreceptor blockade potentiates the ability of the 5-HT reuptake inhibitor citalopram to increase nerve terminal output of 5-HT in vivo: a microdialysis study. J Neurochem. 1993;60(2):776–779.
   PubMed Web of Science ®Google Scholar
• Poul EL, Laaris N, Doucet E, et al. Early desensitization of somato-dendritic 5-HT1A autoreceptors in rats treated with fluoxetine or paroxetine. Naunyn Schmiedebergs Arch Pharmacol. 1995;352(2):141–148.
   PubMed Web of Science ®Google Scholar
• Albert P, Lembo P, Storring J, et al. The 5-HT1A receptor: Signaling, desensitization, and gene transcription. Neuropsychopharmacology. 1996;14(1):19–25.
   PubMed Web of Science ®Google Scholar
• Blier P, Piñeyro G, el Mansari M, et al. Role of somatodendritic 5-HT autoreceptors in modulating 5-HT neurotransmission. Ann N Y Acad Sci. 1998;861:204–216.
   PubMed Web of Science ®Google Scholar
• Berney A, Nishikawa M, Benkelfat C, et al. An index of 5-HT synthesis changes during early antidepressant treatment: alpha-[11C]methyl-L-tryptophan PET study . Neurochem Int. 2008;52(4-5):701–708.
   PubMed Web of Science ®Google Scholar
• Beique J-C, Blier P, De Montigny C, et al. Potentiation by (-)pindolol of the activation of postsynaptic 5-HT(1A) receptors induced by venlafaxine. Neuropsychopharmacology. 2000;23(3):294–306.
   PubMed Web of Science ®Google Scholar
• Arborelius L, Linner L, Wallsten C, et al. Partial 5-HT1A receptor agonist properties of (-)pindolol in combination with citalopram on serotonergic dorsal raphe cell firing in vivo . Psychopharmacology (Berl).). 2000;151(1):77–84.
   PubMed Web of Science ®Google Scholar
• Portella MJ, de Diego-Adeliño J, Ballesteros J, et al. Can we really accelerate and enhance the selective serotonin reuptake inhibitor antidepressant effect? A randomized clinical trial and a meta-analysis of pindolol in nonresistant depression. J Clin Psychiatry. 2011;72(7):962–969.
   PubMed Web of Science ®Google Scholar
• Martiny K, Lunde M, Bech P, et al. A short-term double-blind randomized controlled pilot trial with active or placebo pindolol in patients treated with venlafaxine for major depression. Nord J Psychiatry. 2012;66(3):147–154.
   PubMed Web of Science ®Google Scholar
• Haddjeri N, de Montigny C, Blier P. Modulation of the firing activity of rat serotonin and noradrenaline neurons by (+/-)pindolol. Biol Psychiatry. 1999;45(9):1163–1169.
   PubMed Web of Science ®Google Scholar
• Cremers TI, Wiersma LJ, Bosker FJ, et al. Is the beneficial antidepressant effect of coadministration of pindolol really due to somatodendritic autoreceptor antagonism? Biol Psychiatry. 2001;50(1):13–21.
   PubMed Web of Science ®Google Scholar
• Newman-Tancredi A, Chaput C, Gavaudan S, et al. Agonist and antagonist actions of (-)pindolol at recombinant, human serotonin(1A) (5-HT(1A)) receptors. Neuropsychopharmacology. 1998;18(5):395–398.
   PubMed Web of Science ®Google Scholar
• Morton RA, Yanagawa Y, Valenzuela CF. Electrophysiological Assessment of Serotonin and GABA Neuron Function in the Dorsal Raphe during the Third Trimester Equivalent Developmental Period in Mice(1,2,3). eNeuro. 2015;2(6):ENEURO.0079-15.2015.
   Web of Science ®Google Scholar
• Bal R, Erdogan S, Theophilidis G, et al. Assessing the effects of the neonicotinoid insecticide imidacloprid in the cholinergic synapses of the stellate cells of the mouse cochlear nucleus using whole-cell patch-clamp recording. Neurotoxicology. 2010;31(1):113–120.
   PubMed Web of Science ®Google Scholar
• Yildirim C, Bal R. ERG Channels Regulate Excitability in Stellate and Bushy Cells of Mice Ventral Cochlear Nucleus. J Membr Biol. 2018;251(5-6):711–722.
   PubMed Web of Science ®Google Scholar
• Cakir Z, Yildirim C, Buran I, et al. Acid-sensing ion channels (ASICs) influence excitability of stellate neurons in the mouse cochlear nucleus. J Comp Physiol A. 2019;205(5):769–781.
   Web of Science ®Google Scholar
• Beck SG, Pan Y-Z, Akanwa AC, et al. Median and dorsal raphe neurons are not electrophysiologically identical. J Neurophysiol. 2004;91(2):994–1005.
   PubMed Web of Science ®Google Scholar
• Katayama J, Yakushiji T, Akaike N. Characterization of the K + current mediated by 5-HT(1A) receptors in the acutely dissociated rat dorsal raphe neurons. Brain Res. 1997;745(1-2):283–292.
   PubMed Web of Science ®Google Scholar
• Penington NJ, Kelly JS, Fox AP. Whole-cell recordings of inwardly rectifying k + currents activated by 5-Htia receptors on dorsal raphe neurones of the adult rat. J. Physiol. 1993;469(1):387–405.
   PubMed Web of Science ®Google Scholar
• Corradetti R, Laaris N, Hanoun N, et al. Antagonist properties of (-)-pindolol and WAY 100635 at somatodendritic and postsynaptic 5-HT1A receptors in the rat brain . Br J Pharmacol. 1998;123(3):449–462.
   PubMed Web of Science ®Google Scholar
• Kobeissy FH. Psychiatric disorders: methods and protocols. New York, NY, USA: Humana Press; 2012.
   Google Scholar
• Porsolt RD, Bertin A, Jalfre M. Behavioral despair in mice: a primary screening test for antidepressants. Arch Int Pharmacodyn Ther. 1977;229(2):327–336.
   PubMedGoogle Scholar
• Leibrock CB, Voelkl J, Kuro-O M, et al. 1,25(OH)2D3 dependent overt hyperactivity phenotype in klotho-hypomorphic mice. Sci. Rep. 2016;6: 1–12.
   PubMed Web of Science ®Google Scholar
• Carola V, D'Olimpio F, Brunamonti E, et al. Evaluation of the elevated plus-maze and open-field tests for the assessment of anxiety-related behaviour in inbred mice. Behav Brain Res. 2002;134(1-2):49–57.
   PubMed Web of Science ®Google Scholar
• Amin B, Nakhsaz A, Hosseinzadeh H. Evaluation of the antidepressant-like effects of acute and sub-acute administration of crocin and crocetin in mice. Avicenna J Phytomed. 2015;5:458–468.
   PubMed Web of Science ®Google Scholar
• Sprouse J, Braselton J, Reynolds L. 5-HT(1A) agonist potential of pindolol: Electrophysiologic studies in the dorsal raphe nucleus and hippocampus. Biol Psychiatry. 2000;47(12):1050–1055.
   PubMed Web of Science ®Google Scholar
• Bayliss D. a, Li YW, Talley EM. Effects of serotonin on caudal raphe neurons: Activation of an inwardly rectifying potassium conductance. J Neurophysiol. 1997;77(3):1349–1361.
   PubMed Web of Science ®Google Scholar
• Yamada K, Kobayashi M, Mori A, et al. Antidepressant-like activity of the adenosine A(2A) receptor antagonist, istradefylline (KW-6002), in the forced swim test and the tail suspension test in rodents. Pharmacol Biochem Behav. 2013;114-115:23–30.
   PubMed Web of Science ®Google Scholar
• Ratajczak P, Kus K, Skurzyńska M, et al. The influence of aripiprazole and venlafaxine on the antidepressant-like effect observed in prenatally stressed rats (animal model of depression). Hum Exp Toxicol. 2018;37(9):972–982.
   PubMed Web of Science ®Google Scholar
• Malikowska N, Fijałkowski Ł, Nowaczyk A, et al. Antidepressant-like activity of venlafaxine and clonidine in mice exposed to single prolonged stress – a model of post-traumatic stress disorder. Pharmacodynamic and molecular docking studies. Brain Res. 2017;1673:1–10.
   PubMed Web of Science ®Google Scholar
• Singh P, Singh TG. Modulation of muscarinic system with serotonin-norepinephrine reuptake inhibitor antidepressant attenuates depression in mice. Indian J Pharmacol. 2015;47(4):388–393.
   PubMed Web of Science ®Google Scholar
• Kędzierska E, Fiorino F, Magli E, et al. New arylpiperazine derivatives with antidepressant-like activity containing isonicotinic and picolinic nuclei: evidence for serotonergic system involvement. Naunyn Schmiedebergs Arch Pharmacol. 2019;392(6):743–754.
   PubMed Web of Science ®Google Scholar
• Barauna SC, Kaster MP, Heckert BT, et al. Antidepressant-like effect of lectin from Canavalia brasiliensis (ConBr) administered centrally in mice. Pharmacol Biochem Behav. 2006;85(1):160–169.
   PubMed Web of Science ®Google Scholar