References
- Taylor BV. The major cause of multiple sclerosis is environmental: genetics has a minor role-yes. Mult Scler. 2011;17(10):1171–1173.
- Wootla B, Eriguchi M, Rodriguez M. Is multiple sclerosis an autoimmune disease? Autoimmune Dis. 2012;2012:1–12.
- Hossain MJ, Tanasescu R, Gran B. Innate immune regulation of autoimmunity in multiple sclerosis: focus on the role of Toll-like receptor 2. J Neuroimmunol. 2017;304:11–20.
- Høglund RA, Maghazachi AA. Multiple sclerosis and the role of immune cells. World J Exp Med. 2014;4(3):27–37.
- Pierson ER, Wagner CA, Goverman JM. The contribution of neutrophils to CNS autoimmunity. Clin Immunol. 2018;189:23–28.
- Mogensen TH. Pathogen recognition and inflammatory signaling in innate immune defenses. Clin Microbiol Rev. 2009;22(2):240–273.
- Kattah MG, Wong MT, Yocum MD, et al. Cytokines secreted in response to Toll‐like receptor ligand stimulation modulate differentiation of human Th17 cells. Arthritis Rheum. 2008;58(6):1619–1629.
- Polman CH, Reingold SC, Banwell B, et al. Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria. Ann Neurol. 2011;69(2):292–302.
- Nyirenda MH, Morandi E, Vinkemeier U, et al. TLR2 stimulation regulates the balance between regulatory T cell and Th17 function: a novel mechanism of reduced regulatory T cell function in multiple sclerosis. J Immunol. 2015;194(12):5761–5774.
- Schnare M, Barton GM, Holt AC, et al. Toll-like receptors control activation of adaptive immune responses. Nat Immunol. 2001;2(10):947–950.
- Reynolds JM, Pappu BP, Peng J, et al. Toll-like receptor 2 signaling in CD4(+) T lymphocytes promotes T helper 17 responses and regulates the pathogenesis of autoimmune disease. Immunity. 2010;32(5):692–702.
- Hasheminia SJ, Zarkesh-Esfahani SH, Tolouei S, et al. Toll like receptor 2 and 4 expression in peripheral blood mononuclear cells of multiple sclerosis patients. Iran J Immunol. 2014;11(2):74–83.
- Andersson Å, Covacu R, Sunnemark D, et al. Pivotal advance: HMGB1 expression in active lesions of human and experimental multiple sclerosis. J Leukoc Biol. 2008;84(5):1248–1255.
- Hertwig L, Borisow N, Stürner K, et al. Neutrophils as potential biomarkers in the differentiation of multiple sclerosis and neuromyelitis optica. Front. Immunol. Conference Abstract: 15th International Congress of Immunology (ICI). DOI:https://doi.org/10.3389/conf.fimmu.2013.02.00945
- Hemmer B, Kerschensteiner M, Korn T. Role of the innate and adaptive immune responses in the course of multiple sclerosis. Lancet Neurol. 2015;14(4):406–419.
- Harbo HF, Gold R, Tintoré M. Sex and gender issues in multiple sclerosis. Ther Adv Neurol Disord. 2013;6(4):237–248.