Angiotensin II type 1 receptor deficiency protects against the impairment of blood–brain barrier in a mouse model of traumatic brain injury

References

• Lingsma HF, Roozenbeek B, Steyerberg EW, et al. Early prognosis in traumatic brain injury: from prophecies to predictions. Lancet Neurol. 2010;9(5):543–554.
   PubMed Web of Science ®Google Scholar
• DeKosky ST, Abrahamson EE, Ciallella JR, et al. Association of increased cortical soluble abeta42 levels with diffuse plaques after severe brain injury in humans. Arch Neurol. 2007;64(4):541–544.
   PubMedGoogle Scholar
• Roberts GW, Gentleman SM, Lynch A, et al. Beta amyloid protein deposition in the brain after severe head injury: implications for the pathogenesis of Alzheimer’s disease. J Neurol Neurosurg Psychiatry. 1994;57(4):419–425.
   PubMed Web of Science ®Google Scholar
• Querfurth HW, LaFerla FM. Alzheimer’s disease. N Engl J Med. 2010;362(4):329–344.
   PubMed Web of Science ®Google Scholar
• Zlokovic BV, Yamada S, Holtzman D, et al. Clearance of amyloid beta-peptide from brain: transport or metabolism?Nat Med. 2000;6(7):718–719.
   Web of Science ®Google Scholar
• Ren Z, Iliff JJ, Yang L, et al. ‘Hit & Run’ model of closed-skull traumatic brain injury (TBI) reveals complex patterns of post-traumatic AQP4 dysregulation. J Cereb Blood Flow Metab. 2013;33(6):834–845.
   PubMed Web of Science ®Google Scholar
• Iliff JJ, Wang M, Liao Y, et al. A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid β. Sci Transl Med. 2012;4:147ra11.
   Web of Science ®Google Scholar
• Plog BA, Dashnaw ML, Hitomi E, et al. Biomarkers of traumatic injury are transported from brain to blood via the glymphatic system. J Neurosci. 2015;35(2):518–526.
   PubMed Web of Science ®Google Scholar
• Ren H, Luo C, Feng Y, et al. Omega-3 polyunsaturated fatty acids promote amyloid-β clearance from the brain through mediating the function of the glymphatic system. Faseb J. 2017;31(1):282–293.
   PubMed Web of Science ®Google Scholar
• Ries M, Sastre M. Mechanisms of Aβ clearance and degradation by glial cells. Front Aging Neurosci. 2016;8:160.
   PubMed Web of Science ®Google Scholar
• Rolyan H, Feike AC, Upadhaya AR, Waha A, et al. Amyloid-β protein modulates the perivascular clearance of neuronal apolipoprotein E in mouse models of Alzheimer’s disease. J Neural Transm (Vienna)). 2011;118(5):699–712.
   PubMed Web of Science ®Google Scholar
• Arbel-Ornath M, Hudry E, Eikermann-Haerter K, et al. Interstitial fluid drainage is impaired in ischemic stroke and Alzheimer’s disease mouse models. Acta Neuropathol. 2013;126(3):353–364.
   PubMed Web of Science ®Google Scholar
• Xie L, Kang H, Xu Q, et al. Sleep drives metabolite clearance from the adult brain. Science. 2013;342(6156):373–377.
   PubMed Web of Science ®Google Scholar
• Deane R, Sagare A, Hamm K, et al. apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain. J Clin Invest. 2008;118(12):4002–4013.
   PubMed Web of Science ®Google Scholar
• Kress BT, Iliff JJ, Xia M, et al. Impairment of paravascular clearance pathways in the aging brain. Ann Neurol. 2014;76(6):845–861.
   PubMed Web of Science ®Google Scholar
• Erdő F, Denes L, de Lange E. Age-associated physiological and pathological changes at the blood–brain barrier: a review. J Cereb Blood Flow Metab. 2017;37(1):4–24.
   PubMed Web of Science ®Google Scholar
• Liu J, Liu S, Matsumoto Y, et al. Angiotensin type 1a receptor deficiency decreases amyloid β-protein generation and ameliorates brain amyloid pathology. Sci Rep. 2015;5:12059.
   PubMed Web of Science ®Google Scholar
• Yuan F, Xu ZM, Lu LY, et al. SIRT2 inhibition exacerbates neuroinflammation and blood–brain barrier disruption in experimental traumatic brain injury by enhancing NF-kappaB p65 acetylation and activation. J Neurochem. 2016;136(3):581–593.
   PubMed Web of Science ®Google Scholar
• Wang Y, Jia J, Ao G, et al. Hydrogen sulfide protects blood–brain barrier integrity following cerebral ischemia. J Neurochem. 2014;129(5):827–838.
   PubMed Web of Science ®Google Scholar
• Yuan J, Wang A, He Y, et al. Cordycepin attenuates traumatic brain injury-induced impairments of blood–brain barrier integrity in rats. Brain Res Bull. 2016;127:171–176.
   PubMed Web of Science ®Google Scholar
• He XF, Liu DX, Zhang Q, et al. Voluntary exercise promotes glymphatic clearance of amyloid beta and reduces the activation of astrocytes and microglia in aged mice. Front Mol Neurosci. 2017;10:144.
   PubMed Web of Science ®Google Scholar
• Wang M, Iliff JJ, Liao Y, et al. Cognitive deficits and delayed neuronal loss in a mouse model of multiple microinfarcts. J Neurosci. 2012;32(50):17948–17960.
   PubMed Web of Science ®Google Scholar
• Bovy N, Blomme B, Freres P, et al. Endothelial exosomes contribute to the antitumor response during breast cancer neoadjuvant chemotherapy via microRNA transfer. Oncotarget. 2015;6(12):10253–10266.
   PubMedGoogle Scholar
• Alluri H, Wiggins-Dohlvik K, Davis ML, et al. Blood–brain barrier dysfunction following traumatic brain injury. Metab Brain Dis. 2015;30(5):1093–1104.
   PubMed Web of Science ®Google Scholar
• Yang L, Guo Y, Wen D, et al. Bone fracture enhances trauma brain injury. Scand J Immunol. 2016;83(1):26–32.
   PubMed Web of Science ®Google Scholar
• Yang L, Wang F, Yang L, et al. HMGB1 a-box reverses brain edema and deterioration of neurological function in a traumatic brain injury mouse model. Cell Physiol Biochem. 2018;46(6):2532–2542.
   PubMedGoogle Scholar
• Liu W, Wang P, Shang C, et al. Endophilin-1 regulates blood–brain barrier permeability by controlling ZO-1 and occludin expression via the EGFR-ERK1/2 pathway. Brain Res. 2014;1573:17–26.
   PubMed Web of Science ®Google Scholar
• Itoh T, Satou T, Nishida S, et al. Expression of amyloid precursor protein after rat traumatic brain injury. Neurol Res. 2009;31(1):103–109.
   PubMed Web of Science ®Google Scholar
• Moore BD, Chakrabarty P, Levites Y, et al. Overlapping profiles of Aβ peptides in the Alzheimer’s disease and pathological aging brains. Alzheimers Res Ther. 2012;4(3):18.
   PubMed Web of Science ®Google Scholar
• Nielsen S, Nagelhus EA, Amiry-Moghaddam M, et al. Specialized membrane domains for water transport in glial cells: high-resolution immunogold cytochemistry of aquaporin-4 in rat brain. J Neurosci. 1997;17(1):171–180.
   PubMed Web of Science ®Google Scholar
• Heppner FL, Ransohoff RM, Becher B. Immune attack: the role of inflammation in Alzheimer disease. Nat Rev Neurosci. 2015;16(6):358–372.
   PubMed Web of Science ®Google Scholar