224
Views
13
CrossRef citations to date
0
Altmetric
Original Articles

Increased systemic immune-inflammation index predicts hemorrhagic transformation in anterior circulation acute ischemic stroke due to large-artery atherosclerotic

, , &
Pages 629-635 | Received 03 Apr 2021, Accepted 24 Jun 2021, Published online: 22 Jul 2021

References

  • Adams HP, Jr, Bendixen BH, Kappelle LJ, et al. Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in acute stroke treatment. Stroke. 1993;24(1):35–41.
  • Rovira A, Grive E, Rovira A, et al. Distribution territories and causative mechanisms of ischemic stroke. Eur Radiol. 2005;15(3):416–426.
  • Von Kummer R, Broderick JP, Campbell BC, et al. The Heidelberg bleeding classification: classification of bleeding events after ischemic stroke and reperfusion therapy. Stroke. 2015;46(10):2981–2986.
  • Jickling GC, Liu D, Stamova B, et al. Hemorrhagic transformation after ischemic stroke in animals and humans. J Cereb Blood Flow Metab. 2014;34(2):185–199.
  • Lu GF, He QW, Shen Y, et al. Potential biomarkers for predicting hemorrhagic transformation of ischemic stroke. Int J Neurosci. 2018;128(1):79–189.
  • Lee SJ, Lee DG. Distribution of atherosclerotic stenosis determining early neurologic deterioration in acute ischemic stroke. PLoS One. 2017;12(9):e0185314.
  • Wolf D, Ley K. Immunity and Inflammation in atherosclerosis. Circ Res. 2019;124(2):315–327.
  • Schaftenaar F, Frodermann V, Kuiper J, et al. Atherosclerosis: the interplay between lipids and immune cells. Curr Opin Lipidol. 2016;27(3):209–215.
  • Song QH, Pan RS, Jin YX, et al. Lymphocyte-to-monocyte ratio and risk of hemorrhagic transformation in patients with acute ischemic stroke. Neurol Sci. 2020; 41(9):2511–2520.
  • Zhang WB, Zeng YY, Wang F, et al. A high neutrophil-to-lymphocyte ratio predicts hemorrhagic transformation of large atherosclerotic infarction in patients with acute ischemic stroke. Aging (Albany NY). 2020;12(3):2428–2439.
  • Zhang RR, Wu XD, Hu WJ, et al. Neutrophil-to-lymphocyte ratio predicts hemorrhagic transformation in ischemic stroke: a meta-analysis. Brain Behav. 2019;9(9):e01382.
  • He WW, Ruan YT, Yuan CX, et al. High neutrophil-to-platelet ratio is associated with hemorrhagic transformation in patients with acute ischemic stroke. Front Neurol. 2019;10:1310.
  • Song QH, Li YS, Wang YN, et al. Increased neutrophil-to-lymphocyte ratios are associated with greater risk of hemorrhagic transformation in patients with acute ischemic stroke. Curr Neurovasc Res. 2018;15(4):326–335.
  • Gong PY, Xie Y, Jiang T, et al. Neutrophil-lymphocyte ratio predicts post-thrombolysis early neurological deterioration in acute ischemic stroke patients. Brain Behav. 2019;9(10):e01426.
  • Duan ZH, Wang HM, Wang Z, Hao YG, et al. Neutrophil-lymphocyte ratio predicts functional and safety outcomes after endovascular treatment for acute ischemic stroke. Cerebrovasc Dis. 2018;45(5-6):221–227.
  • Brooks SD, Spears C, Cummings C, et al. Admission neutrophil-lymphocyte ratio predicts 90 day outcome after endovascular stroke therapy. J Neurointerv Surg. 2014;6(8):578–583.
  • Yang YL, Wu CH, Hsu PF, et al. Systemic immune-inflammation index (SII) predicted clinical outcome in patients with coronary artery disease. Eur J Clin Invest. 2020;50(5):e13230.
  • Hou DL, Wang CJ, Ye XF, et al. Systemic immune-inflammation index (SII) but not platelet-albumin-bilirubin (PALBI) grade is associated with severity of acute ischemic stroke (AIS). Int J Neurosci. 2020:1–6.
  • Hatano S. Experience from a multicentre stroke register: a preliminary report. Bull World Health Organ. 1976;54(5):541–553.
  • Lee DK, Kim JS, Kwon SU, et al. Lesion patterns and stroke mechanism in atherosclerotic middle cerebral artery disease: early diffusion-weighted imaging study. Stroke. 2005;36(12):2583–2588.
  • Gorelick PB, Wong KS, Bae HJ, et al. Large artery intracranial occlusive disease: a large worldwide burden but a relatively neglected frontier. Stroke. 2008;39(8):2396–2399.
  • Banerjee C, Chimowitz MI. Stroke caused by atherosclerosis of the major intracranial arteries. Circ Res. 2017;120(3):502–513.
  • Deng QW, Liu YK, Zhang YQ, et al. Low triglyceride to high-density lipoprotein cholesterol ratio predicts hemorrhagic transformation in large atherosclerotic infarction of acute ischemic stroke. Aging (Albany NY). 2019;11(5):1589–1601.
  • Caprio FZ, Sorond FA. Cerebrovascular disease: primary and secondary stroke prevention. Med Clin North Am. 2019;103(2):295–308.
  • Witztum JL, Lichtman AH. The influence of innate and adaptive immune responses on atherosclerosis. Annu Rev Pathol. 2014;9:73–102.
  • Kobiyama K, Ley K. Atherosclerosis. Circ Res. 2018;123(10):1118–1120.
  • Zhai Y, Shen XD, Hancock WW, et al. CXCR31 + CD4+ T cells mediate innate immune function in the pathophysiology of liver ischemia/reperfusion injury. J Immunol. 2006;176(10):6313–6322.
  • Zhai Y, Shen X-d, O’Connell R, et al. Cutting edge: TLR4 activation mediates liver ischemia/reperfusion inflammatory response via IFN regulatory factor 3-dependent MyD88-independent pathway. J Immunol. 2004;173(12):7115–7119.
  • Mercuri M, Ciuffetti G, Lombardini R, et al. Do leukocytes have a role in the cerebral no-reflow phenomenon?J Neurol Neurosurg Psychiatry. 1990;53(6):536.
  • Arumugam TV, Granger DN, Mattson MP. Stroke and T-cells. Neuromolecular Med. 2005;7(3):229–242.
  • Huang J, Upadhyay UM, Tamargo RJ. Inflammation in stroke and focal cerebral ischemia. Surg Neurol. 2006;66(3):232–245.
  • Perera MN, Ma HK, Arakawa S, et al. Inflammation following stroke. J Clin Neurosci. 2006;13(1):1–8.
  • Morotti A, Phuah CL, Anderson CD, et al. Leukocyte count and intracerebral hemorrhage expansion. Stroke. 2016;47(6):1473–1478.
  • Yamamoto Y, Osanai T, Nishizaki F, et al. Matrix metalloprotein-9 activation under cell-to-cell interaction between endothelial cells and monocytes: possible role of hypoxia and tumor necrosis factor-α. Heart Vessels. 2012;27(6):624–633.
  • Keep RF, Hua Y, Xi GH. Intracerebral haemorrhage: mechanisms of injury and therapeutic targets. Lancet Neurol. 2012;11(8):720–731.
  • Park BJ, Shim JY, Lee HR, et al. Relationship of neutrophil-lymphocyte ratio with arterial stiffness and coronary calcium score . Clin Chim Acta. 2011;412(11-12):925–929.
  • Yip HK, Chen SS, Liu JS, et al. Serial changes in platelet activation in patients after ischemic stroke: role of pharmacodynamic modulation. Stroke. 2004;35(7):1683–1687.
  • Fateh-Moghadam S, Htun P, Tomandl B, et al. Hyperresponsiveness of platelets in ischemic stroke. Thromb Haemost. 2007;97(06):974–978.
  • Marquardt L, Ruf A, Mansmann U, et al. Course of platelet activation markers after ischemic stroke. Stroke. 2002;33(11):2570–2574.
  • Yilmaz G, Arumugam TV, Stokes KY, et al. Role of T lymphocytes and interferon-gamma in ischemic stroke. Circulation. 2006;113(17):2105–2112.
  • Li N. Platelet-lymphocyte cross-talk. J Leukoc Biol. 2008;83(5):1069–1078.
  • Lowe JB. Glycan-dependent leukocyte adhesion and recruitment in inflammation. Curr Opin Cell Biol. 2003;15(5):531–538.
  • Ley K, Laudanna C, Cybulsky MI, et al. Getting to the site of inflammation: the leukocyte adhesion cascade updated. Nat Rev Immunol. 2007;7(9):678–689.
  • Li N, Ji Q, Hjemdahl P. Platelet-lymphocyte conjugation differs between lymphocyte subpopulations. J Thromb Haemost. 2006;4(4):874–881.
  • Salas-Perdomo A, Miró-Mur F, Urra X, et al. T cells prevent hemorrhagic transformation in ischemic stroke by P-selectin binding. Arterioscler Thromb Vasc Biol. 2018;38(8):1761–1771.
  • Arboix A, García-Eroles L, Massons J, et al. Predictive clinical factors of in-hospital mortality in 231 consecutive patients with cardioembolic cerebral infarction. Cerebrovasc Dis. 1998;8(1):8–13.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.