References
- Harada T, Shinohara M, Nakamura S, Shimada M, Oka M. Immunohistochemical detection of desmosomes in oral squamous cell carcinomas: correlation with differentiation, mode of invasion, and metastatic potential. Int J Oral Maxillofac Surg 1992; 21: 346–349
- Carlos de Vicente J, Herrero-Zapatero A, Fresno M F, Lopez-Arranz J S. Expression of cyclin D1 and Ki-67 in squamous cell carcinoma of the oral cavity: clinicopathological and prognostic significance. Oral Oncol 2002; 38: 301–308
- Shintani S, Mihara M, Nakahara Y, et al. Expression of cell cycle control proteins in normal epithelium, premalignant and malignant lesions of the oral cavity. Oral Oncol 2002; 38: 235–243
- Xu J, Gimenez-Conti I B, Cunninghan J E, et al. Alterations of p53, cyclin D1, Rb, and H-ras in human oral carcinomas related to tobacco use. Cancer 1998; 83: 204–212
- Lam K Y, Ng I O, Yuen A P, Kwong D L, Wei W. Cyclin D1 expression in oral squamous cell carcinomas: clinicopathological relevance and correlation with p53 expression. J Oral Pathol Med 2000; 29: 167–172
- Xie X, Clausen O P, De Angelis P, Boysen M. The prognostic value of spontaneous apoptosis, Bax, Bcl-2, and p53 in oral squamous cell carcinoma of the tongue. Cancer 1999; 86: 913–920
- Ravi D, Nalinakumari K R, Rajaram R S, Nair M K, Pillai M R. Expression of programmed cell death regulatory p53 and bcl-2 proteins in oral lesions. Cancer Lett 1996; 105: 139–146
- Jemal A, Murray T, Ward E, et al. Cancer statistics, 2005. CA Cancer J Clin 2005; 55: 10–30
- Natsugoe S, Aikou T, Shimada M, et al. Expression of desmoglein I in squamous cell carcinoma of the esophagus. J Surg Oncol 1994; 57: 105–110
- Hiraki A, Shinohara M, Ikebe T, Nakamura S, Kurahara S, Garrod D R. Immunohistochemical staining of desmosomal components in oral squamous cell carcinomas and its association with tumour behaviour. Br J Cancer 1996; 73: 1491–1497
- Pittella F, Katsube K, Tekemura T, et al. Perinuclear and cytoplasmic distribution of desmoglein in esophageal squamous cell carcinomas. Pathol Res Pract 2001; 197: 85–91
- Chang H W, Chow V, Lam K Y, Wei W I, Yuen A. Loss of E-cadherin expression resulting from promoter hypermethylation in oral tongue carcinoma and its prognostic significance. Cancer 2002; 94: 386–392
- Yamada K, Jordan R, Mori M, Speight P M. The relationship between E-cadherin expression, clinical stage and tumour differentiation in oral squamous cell carcinoma. Oral Dis 1997; 3: 82–85
- Bagutti C, Speight P M, Watt F M. Comparison of integrin, cadherin, and catenin expression in squamous cell carcinomas of the oral cavity. J Pathol 1998; 186: 8–16
- Kuo M Y, Lin C Y, Hahn L J, Cheng S J, Chiang C P. Expression of cyclin D1 is correlated with poor prognosis in patients with areca quid chewing-related oral squamous cell carcinomas in Taiwan. J Oral Pathol Med 1999; 28: 165–169
- Schoelch M L, Regezi J A, Dekker N P, et al. Cell cycle proteins and the development of oral squamous cell carcinoma. Oral Oncol 1999; 35: 333–342
- Smith B D, Smith G L, Carter D, et al. Molecular marker expression in oral and pharyngeal squamous cell carcinoma. Arch Otolaryngol Head Neck Surg 2001; 127: 780–785
- El-Naggar A K, Lai S, Clayman G L, et al. Expression of p16, Rb, and cyclin D1 gene products in oral and laryngeal squamous carcinoma: biological and clinical implications. Hum Pathol 1999; 30: 1013–1018
- Kapranos N, Stathopoulos G P, Manolopoulos L, et al. p53, p21, p27 protein expression in head and neck cancer and their prognostic value. Anticancer Res 2001; 21: 521–528
- Xie X, Clausen O P, Boysen M. Prognostic significance of p21WAF1/CIP1 expression in tongue squamous cell carcinomas. Arch Otolaryngol Head Neck Surg 2002; 128: 897–902
- Choi H R, Tucker S A, Huang Z, et al. Differential expressions of cyclin-dependent kinase inhibitors (p27 and p21) and their relation to p53 and Ki-67 in oral squamous tumorigenesis. Int J Oncol 2003; 22: 409–414
- Kuo M Y, Hsu H Y, Kok S H, et al. Prognostic role of p27 (Kip1) expression in oral squamous cell carcinoma in Taiwan. Oral Oncol 2002; 38: 172–178
- Tamura N, Dong Y, Sui L, et al. Cyclin-dependent kinase inhibitor p27 is related to cell proliferation and prognosis in laryngeal squamous cell carcinomas. J Laryngol Otol 2001; 115: 400–406
- Venkatesan T K, Kuropkat C, Caldarelli D D, et al. Prognostic significance of p27 expression in carcinoma of the oral cavity and oropharynx. Laryngoscope 1999; 109: 1329–1333
- Mineta H, Miura K, Suzuki I, et al. Low p27 expression correlates with poor prognosis for patients with oral tongue squamous cell carcinoma. Cancer 1999; 85: 1011–1017
- Kudo Y, Kitajima S, Ogawa I, Miyauchi M, Takata T. Down-regulation of Cdk inhibitor p27 in oral squamous cell carcinoma. Oral Oncol 2005; 41: 105–116
- Harada K, Supriatno, Yoshida H, Sato M. Low p27Kip1 expression is associated with poor prognosis in oral squamous cell carcinoma. Anticancer Res 2002; 22: 2985–2989
- Ai L, Stephenson K K, Ling W, et al. The p16 (CDKN2a/INK4a) tumor-suppressor gene in head and neck squamous cell carcinoma: a promoter methylation and protein expression study in 100 cases. Mod Pathol 2003; 16: 944–957
- Gonzalez-Moles M A, Ruiz-Avila I, Martinez J A, et al. P21WAF1/CIP1 protein and tongue cancer prognosis. Anticancer Res 2004; 24: 3225–3231
- Nagler R, Kerner H, Laufer D, Ben-Eliezer S, Minkov I, Ben-Itzhak O. Squamous cell carcinoma of the tongue: the prevalence and prognostic roles of p53, Bcl-2, c-erbB-2 and apoptotic rate as related to clinical and pathological characteristics in a retrospective study. Cancer Lett 2002; 186: 137–150
- Staibano S, Mignogna M D, Lo Muzio L, et al. Overexpression of cyclin-D1, bcl-2, and bax proteins, proliferating cell nuclear antigen (PCNA), and DNA-ploidy in squamous cell carcinoma of the oral cavity. Hum Pathol 1998; 29: 1189–1194
- Lorro L L, Vintermyr O K, Liavaag P G, Jonsson R, Johannessen A C. Oral squamous cell carcinoma is associated with decreased bcl-2/bax expression ratio and increased apoptosis. Hum Pathol 1999; 30: 1097–1105
- Ravi D, Ramadas K, Mathew B S, Nalinakumari K R, Nair M K, Pillai M R. Angiogenesis during tumor progression in the oral cavity is related to reduced apoptosis and high tumor cell proliferation. Oral Oncol 1998; 34: 543–548
- Jordan R C, Catzavelos G C, Barrett A W, Speight P M. Differential expression of bcl-2 and bax in squamous cell carcinomas of the oral cavity. Eur J Cancer B Oral Oncol 1996; 32B: 394–400
- Sulkowska M, Famulski W, Sulkowski S, et al. Correlation between Bcl-2 protein expression and some clinicopathological features of oral squamous cell carcinoma. Pol J Pathol 2003; 54: 49–52
- Eisen M B, Spellman P T, Brown P O, Botstein D. Cluster analysis and display of genome-wide expression patterns. Proc Natl Acad Sci USA 1998; 95: 14863–14868
- Liu C L, Prapong W, Natkuman Y, et al. Software tools for high-throughput analysis and archiving of immunohistochemistry staining data obtained with tissue microarrays. Am J Pathol 2002; 161: 1557–1565
- Au N H, Gown A M, Cheang M, et al. P63 expression in lung carcinoma: a tissue microarray study of 408 cases. Appl Immunohistochem Mol Morphol 2004; 12(3)240–247
- Makretsov N A, Huntsman D G, Nielsen T O, et al. Hierarchical clustering analysis of tissue microarray immunostaining data identifies prognostically significant groups of breast carcinoma. Clin Cancer Res 2004; 10: 6143–6151
- Alkushi A, Irving J, Hsu F, et al. Immunoprofile of cervical and endometrial adenocarcinomas using a tissue microarray. Virchows Arch 2003; 442: 271–277