Role of intravenous lipid emulsions in the management of calcium channel blocker and β-blocker overdose: 3 years experience of a university hospital

References

• Weinberg GL, Vade Boncouer T, Ramaraju GA, Garcia-Amaro MF, Cwik MJ. Pretreatment or resuscitation with a lipid infusion shifts the dose-response to bupivacaine-induced asystole in rats. Anesthesiology 1998;88:1071–5
   PubMed Web of Science ®Google Scholar
• Bourne E, Wright C, Royse C. A review of local anesthetic cardiotoxicity and treatment with lipid emulsion. Local Reg Anesth 2010;3:11–19
   PubMedGoogle Scholar
• Warren JA, Thoma RB, Georgescu A, Shah SJ. Intravenous lipid infusion in the successful resuscitation of local anesthetic-induced cardiovascular collapse after supraclavicular brachial plexus block. Anesth Analg 2008;106:1578–80
   PubMed Web of Science ®Google Scholar
• Ciechanowicz S, Patil V. Lipid emulsion for local anesthetic systemic toxicity. Anesthesiol Res Pract 2012;13:784–9
   Google Scholar
• Intralipid 20% - Food and Drug Administration. Available from www.accessdata.fda.gov/. Access January 20,2015 page 3–20
   Google Scholar
• Waring WS. Intravenous lipid administration for drug-induced toxicity: a critical review of the existing data. Expert Rev Clin Pharmacol 2012;5:437–44
   PubMed Web of Science ®Google Scholar
• Litonius ES. Treatment of acute intoxication with intravenous lipid emulsion-animal and human studies. Acad Diss. U of Helsinki, ’012 Helsinki: Unigrafia Oy; 2012
   Google Scholar
• Pennec JP, Guillouet M, Rannou F, Arvieux CC, Gueret G. Hemodynamic effects of lipid emulsion after local anesthetic intoxication may be due to a direct effect of fatty acids on myocardial voltage-dependent calcium channels. Can J Anaesth 2010;57:947
   PubMed Web of Science ®Google Scholar
• Coat M, Pennec JP, Guillouet M, Arvieux CC, Gueret G. Haemodynamic effects of intralipid after local anaesthetics intoxication may be due to a direct effect of fatty acids on myocardial voltage-dependent calcium channels. Ann Fr Anesth Reanim 2010;29:661
   PubMedGoogle Scholar
• Harvey M, Cave G. Intralipid outperforms sodium bicarbonate in a rabbit model of clomipramine toxicity. Ann Emerg Med 2007;49:178–85
   PubMed Web of Science ®Google Scholar
• Rosenblatt MA, Abel M, Fischer GW, et al. Successful use of a 20% lipid emulsion resuscitate a patient after a presumed bupivacaine-related cardiac arrest. Anesthesiology 2006;105:217–18
   PubMed Web of Science ®Google Scholar
• Weinberg GL. Lipid emulsion infusion. Resuscitation for local anesthetic and other drug overdose. Anesthesiology 2012;117:180–7
   PubMed Web of Science ®Google Scholar
• Brontein A, Spyker D, Cantilena L, et al. 2010 annual report of the American Association of Poison Control Centers’ National Poison Data System (NPDS): 28th annual report. Clin Toxicol 2010;49:910–41
   Google Scholar
• Mowry JB, Spyker DA, Cantilena L, Bailey JE, Ford M. Annual Report of the American Association of Poison Control Centers’ National Poison Data System (NPDS): 30th Annual Report Clinical Toxicology 2012. Clin Taxicol (Phila) 2013;51:949–1229
   PubMed Web of Science ®Google Scholar
• Young AC, Velez LI, Kleinschmidt KC. Intravenous fat emulsion therapy for intentional sustained-release verapamil overdose. Resuscitation 2009;80:591–3
   PubMed Web of Science ®Google Scholar
• Tebbutt S, Harvey M, Nicholson T, Cave G. Intralipid prolongs survival in a rat model of verapamil toxicity. Acad Emerg Med 2006;13:134–9
   PubMed Web of Science ®Google Scholar
• Orr K, Bailie R. The use of Intralipid in the management of a mixed overdose. J Intens Care Soc 2010;11:268–9
   Google Scholar
• West P, McKeown N, Hendrickson R. Iatrogenic lipid emulsion overdose in a case of amlodipine poisoning. Clin Toxicol 2010;48:393–6
   PubMed Web of Science ®Google Scholar
• Tintinalli J, Stapczynski J, Ma OJ, Cline D, Cydulka R, Meckler G. Beta blockers and calcium channel blockers. In: Tintinalli JE, editor, Tintinalli’s emergency medicine: a comprehensive study guide. 7th edition. New York USA: McGraw-Hill Professional; 2010. p 2570–89
   Google Scholar
• Ellenhorn MJ, Schonwald S, Ordog G, Wassenberger J. Elenhorn’s medical toxicology: Chapter 32. In: Matthew J Ellenhorn, Jonathan Wasserberger, Seth Schonwald, editors, Antiarrhytmic drugs. Beta blockers toxicity. Philadelphia USA: Williams & Wilkins; 19097. p 1143–6
   Google Scholar
• Cave G, Harvey MG, Castle CD. The role of fat emulsion therapy in a rodent model of propranolol toxicity: a preliminary study. J Med Toxicol 2006;2:4–7
   PubMedGoogle Scholar
• Bania TC, Chu J, Perez E, Perez E, Perez E, et al. Hemodynamic effects of intravenous fat emulsion in an animal model of severe verapamil toxicity resuscitated with atropine, calcium, and saline. Acad Emerg Med 2007;14:105–15
   PubMed Web of Science ®Google Scholar
• Bouchard NC, Forde J, Hoffman RS. Carvedilol overdose with quantitative confirmation. Basic Clin Pharmacol Toxicol 2008;103:102–3
   PubMed Web of Science ®Google Scholar
• Browne A, Harvey M, Cave G. Intravenous lipid emulsion does not augment blood pressure recovery in a rabbit model of metoprolol toxicity. J Med Toxicol 2010;6:373–8
   PubMedGoogle Scholar
• Palatnick W, Jelic T. Emergency department management of calcium-channel blocker, beta blocker, and digoxin toxicity. Emerg Med Pract 2014;16:1–19
   PubMedGoogle Scholar
• Gunja N, Graudins A. Management of cardiac arrest following poisoning. Emerg Med Australas 2011;23:16–22
   PubMed Web of Science ®Google Scholar
• Weinberg GL. Treatment of local anesthetic systemic toxicity (LAST). Reg. Anesth Pain Med 2010;35:188–93
   PubMed Web of Science ®Google Scholar
• Weinberg GL. Intravenous lipid emulsion: why wait to save a life? Emerg Med Australas 2011;23:113–15
   PubMed Web of Science ®Google Scholar
• Bern S, Weinberg G. Local anesthetic toxicity and lipid resuscitation in pregnancy. Curr Opin Anaesthesiol 2011;24:262–7
   PubMed Web of Science ®Google Scholar
• Ludot H, Tharin JH, Belouadah M, et al. Successful resuscitation after ropivacaine and lidocaine-induced ventricular arrhythmia following posterior lumbar plexus block in a child. Anesth Analg 2008;106:1572–4
   PubMed Web of Science ®Google Scholar
• Hellig J, Von Watzdorf I, Lahri S, Vallabh K, Allgaier RL. Chewing the fat: a case report on intravenous lipid emulsion to reverse cardiotoxicity from intentional amitriptyline overdose. Afr J Emerg Med 2012;2:159–62
   Google Scholar
• Weinberg G, Ripper R, Feinstein DL, Hoffman W. Lipid emulsion infusion rescues dogs from bupivacaine-induced cardiac toxicity. Reg Anesth Pain Med 2003;28:198–202
   PubMed Web of Science ®Google Scholar