Advanced search
Publication Cover
Scandinavian Journal of Clinical and Laboratory Investigation Volume 62, 2002 - Issue 7
Submit an article Journal homepage
179
Views
81
CrossRef citations to date
0
Altmetric
Research Article

Soluble CD163: a marker molecule for monocyte/macrophage activity in disease

H. J. Møller Department of Clinical Biochemistry, Aarhus University Hospital, Denmark; Department of Biochemistry, Academic Medical Center, University of Amsterdam, The Netherlands; Department of Hepatology and Gastroenterology V, Aarhus University Hospital, Denmark;
,
H. Aerts Department of Clinical Biochemistry, Aarhus University Hospital, Denmark; Department of Biochemistry, Academic Medical Center, University of Amsterdam, The Netherlands; Department of Hepatology and Gastroenterology V, Aarhus University Hospital, Denmark;
,
H. Grøbæk Department of Clinical Biochemistry, Aarhus University Hospital, Denmark; Department of Biochemistry, Academic Medical Center, University of Amsterdam, The Netherlands; Department of Hepatology and Gastroenterology V, Aarhus University Hospital, Denmark;
,
N. A. Peterslund Department of Clinical Biochemistry, Aarhus University Hospital, Denmark; Department of Biochemistry, Academic Medical Center, University of Amsterdam, The Netherlands; Department of Hepatology and Gastroenterology V, Aarhus University Hospital, Denmark;
,
P. Hyltoft Petersen Department of Haematology B, Aarhus University Hospital, Denmark; Department of Clinical Biochemistry, Odense University Hospital, Denmark; Department of Clinical Biochemistry, Randers Central Hospital, Denmark; Department of Endocrinology and Metabolism C, Aarhus University Hospital, Denmark; Department of Medical Biochemistry, University of Aarhus, Denmark
,
N. Hornung Department of Clinical Biochemistry, Aarhus University Hospital, Denmark; Department of Biochemistry, Academic Medical Center, University of Amsterdam, The Netherlands; Department of Hepatology and Gastroenterology V, Aarhus University Hospital, Denmark;
,
L. Renjmark Department of Haematology B, Aarhus University Hospital, Denmark; Department of Clinical Biochemistry, Odense University Hospital, Denmark; Department of Clinical Biochemistry, Randers Central Hospital, Denmark; Department of Endocrinology and Metabolism C, Aarhus University Hospital, Denmark; Department of Medical Biochemistry, University of Aarhus, Denmark
,
E. Jabbarpour Department of Haematology B, Aarhus University Hospital, Denmark; Department of Clinical Biochemistry, Odense University Hospital, Denmark; Department of Clinical Biochemistry, Randers Central Hospital, Denmark; Department of Endocrinology and Metabolism C, Aarhus University Hospital, Denmark; Department of Medical Biochemistry, University of Aarhus, Denmark
&
S. K. Moestrup Department of Haematology B, Aarhus University Hospital, Denmark; Department of Clinical Biochemistry, Odense University Hospital, Denmark; Department of Clinical Biochemistry, Randers Central Hospital, Denmark; Department of Endocrinology and Metabolism C, Aarhus University Hospital, Denmark; Department of Medical Biochemistry, University of Aarhus, Denmark
 show all
Pages 29-33 | Published online: 08 Jul 2009

REFERENCES

  • Kristiansen M, Graversen J, Jacobsen J, Sonne 0, Hoffman HJ, Law SKA, Moestrup SK. Identifica-tion of the haemoglobin scavenger receptor. Nature 2001; 409: 198–201.
  • Law SK, Micklem KJ, Shaw JM, Zhang XP, Dong Y, Willis AC, Mason DY. A new macro-phage differentiation antigen which is a member of the scavenger receptor superfamily. Eur J Immunol 1993; 9: 2320–5.
  • Ritter M, Buechler C, Langmann T, Schmitz G. Genomic organization and chromosomal localiza-tion of the human CD163 (M130) gene: a member of the scavenger receptor cysteine-rich super-family. Biochem Biophys Res Commun 1999; 260: 466–74.
  • Buechler C, Ritter M, Orso E, Langmann T, Klucken J, Schmitz G. Regulation of scavenger receptor CD163 expression in human monocytes and macrophages by pro- and antiinflammatory stimuli. J Leukoc Biol 2000; 67: 97–103.
  • H6gger P, Dreier J, Droste A, Buck F, Sorg C. Identification of the integral membrane protein RM3/1 on human monocytes as a glucocorticoid-inducible member of the scavenger receptor cysteine-rich family (CD163). J Immunol 1998; 161: 1883–905.
  • Sulahian TH, Hogger P, Wahner AE, Wahner AE, Goulding NJ, Sorg C, Droste A, Stehling M, Wallace PK, Morganelli PM, Guyre PM. Human monocytes express CD163, which is upregulated by IL-10 and identical to p155. Cytokine 2000; 12: 13 12 — 21.
  • Droste A, Sorg C, H6gger P. Shedding of CD163, a novel regulatory mechanism for a member of the scavenger receptor cysteine-rich family. Biochem Biophys Res Commun 1999; 256: 110–3.
  • Sulahian TH, Hintz KA, Wardwell K, Guyre PM. Development of an ELISA to measure soluble CD163 in biological fluids. J Immunol Methods 2001; 252: 25–31.
  • Sottrup-Jensen L. Determination of halfcystine in proteins as cysteine from reducing hydrolyzates. Biochem Mol Biol hit 1993; 30: 789–94.
  • Moller HJ, Peterslund NA, Graversen JH, Moestrup SK. Identification of the hemoglobin scavenger receptor/CD163 as a natural soluble protein in plasma. Blood 2002; 99: 378–80.
  • Moller HJ, Hold K, Moestrup SK. Characterisa-tion of an enzyme linked immunosorbent assay for soluble CD163. Scand J Clin Lab Invest 2002; 62: 293 —300.
  • Moller HJ, Hyltoft Petersen P, Rejnmark L, Moestrup SK. Biological variation of soluble CD163. Scand J Clin Lab Invest 2002. Submitted for publication.
  • H6gger P, Sorg C. Soluble CD163 inhibits phorbol ester-induced lymphocyte proliferation. Biochem Biophys Res Commun 2001; 288: 841–3.
  • Stover CM, Schleypen J, Gronlund J, Speicher MR, Schwaeble WJ, Holmskov U. Assignment of CD163B, the gene encoding M160, a novel scavenger receptor, to human chromosome 12p13.3 by in situ hybridiza-tion and somatic cell hybrid analysis. Cytogenet Cell Genet 2000; 90: 246–7.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.