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Research Article

Lipoprotein production by the heart: a novel pathway of triglyceride export from cardiomyocytes

Pages 35-40 | Published online: 08 Jul 2009

REFERENCES

  • Wetterau JR, Lin MC, Jamil H. Microsomal triglyceride transfer protein. Biochim Biophys Acta 1997; 1345(2): 136–50.
  • Nielsen LB, Kahn D, Duell T, Weier HU, Taylor S, Young SG. Apolipoprotein B gene expression in a series of human apolipoprotein B transgenic mice generated with recA-assisted restriction endonuclease cleavage-modified bacterial artificial chromosomes. An intestine-specific enhancer ele-ment is located between 54 and 62 kilobases 5' to the structural gene. J Biol Chem 1998; 273(34): 21800–7.
  • Nielsen LB, McCormick SP, Pierotti V, Tam C, Gunn MD, Shizuya H, et al. Human apolipopro-tein B transgenic mice generated with 207- and 145-kilobase pair bacterial artificial chromosomes. Evidence that a distant 5'-element confers appro-priate transgene expression in the intestine. J Biol Chem 1997; 272(47): 29752–8.
  • Nielsen LB, Veniant M, Boren J, Raabe M, Wong JS, Tam C, et al. Genes for apolipoprotein B and microsomal triglyceride transfer protein are expressed in the heart: evidence that the heart has the capacity to synthesize and secrete lipo-proteins. Circulation 1998; 98(1): 13–16.
  • Nielsen LB, Sullivan M, Vanni-Reyes T, Goldberg U, Young SG. The DNA sequences required for apolipoprotein B expression in the heart are distinct from those required for expression in the intestine. J Mol Cell Cardiol 1999; 31(4): 695–703.
  • Boren J, Veniant MM, Young SG. Apo B100-containing lipoproteins are secreted by the heart. J Clin Invest 1998; 101(6): 1197–202.
  • McCormick SP, Nielsen LB. Expression of large genomic clones in transgenic mice: new insights into apolipoprotein B structure, function and regulation. Curr Opin Lipidol 1998; 9(2): 103–11.
  • Heyliger CE, Scarim AL, Eymer VP, Skau KA, Powell DM. Characteristics of the myocardial PM-FABP: effect of diabetes mellitus. Mol Cell Biochem 1997; 176(1-2): 281–6.
  • Heyliger CE, Rodrigues B, McNeill JH. Effect of choline and methionine treatment on cardiac dysfunction of diabetic rats. Diabetes 1986; 35(10): 1152–7.
  • Nielsen LB, Bartels ED, Bollano E. Overexpres-sion of apolipoprotein B in the heart impedes cardiac triglyceride accumulation and development of cardiac dysfunction in diabetic mice. J Biol Chem 2002; 227(30): 27014–20.
  • Bjorkegren J, Veniant M, Kim SK, Withycombe SK, Wood PA, Hellerstein MK, et al. Lipoprotein secretion and triglyceride stores in the heart. J Biol Chem 2001; 276(42): 38511–7.
  • Suzuki J, Shen WJ, Nelson BD, Selwood SP, Murphy GM, Kanefara H, et al. Cardiac gene expression profile and lipid accumulation in response to starvation. Am J Physiol Endocrinol Metab 2002; 283(1): E94 —102.
  • Unger RH, Orci L. Diseases of liporegulation: new perspective on obesity and related disorders. FASEB J 2001; 15(2): 312–21.
  • van der Vusse GJ, Glatz JF, Stam HC, Reneman RS. Fatty acid homeostasis in the normoxic and ischemic heart. Physiol Rev 1992; 72(4): 881–940.
  • Barger PM, Kelly DP. Ppar signaling in the control of cardiac energy metabolism. Trends Cardiovasc Med 2000; 10(6): 238–45.
  • Bilheimer DW, Buja LM, Parkey RW, Bonte FJ, Willerson JT. Fatty acid accumulation and abnormal lipid deposition in peripheral and border zones of experimental myocardial infarcts. J Nucl Med 1978; 19(3): 276–83.
  • Nielsen LB, Perko M, Arendrup HA, Andersen CB. Microsomal triglyceride transfer protein gene expression and triglyceride accumulation in hypoxic human hearts. Arterioscler Thromb Vasc Biol. In press.

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