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Original Article

Characterization of SCCA-IgM as a biomarker of liver disease in an Asian cohort of patients

, , , , , , , , & show all
Pages 204-210 | Received 19 Sep 2017, Accepted 21 Jan 2018, Published online: 30 Jan 2018

References

  • Stanaway JD, Faxman AD, Naghavi M, et al. The global burden of viral hepatitis from 1990 to 2013: findings from the Global Burden of Disease Study 2013. Lancet. 2016;388:1081–1088.
  • World Health Organization. Fact sheet on hepatitis 2016. Available from: http://www.who.int/hepatitis/en/
  • Omata M, Lesmana LA, Tateishi R, et al. Asian Pacific Association for the Study of the Liver consensus recommend`ations on hepatocellular carcinoma. Hepatol Int. 2010;4:439–474.
  • Martini A, Gallotta A, Pontisso P, et al. Clinical applications of squamous cell carcinoma antigen-immunoglobulins M to monitor chronic hepatitis C. World J Hepatol. 2015;7:2913–2919.
  • Vidalino L, Doria A, Quarta S, et al. SERPINB3, apoptosis and autoimmunity. Autoimmun Rev. 2009;9:108–112.
  • Catanzaro JM, Sheshadri N, Pan JA, et al. Oncogenic Ras induces inflammatory cytokine production by upregulating the squamous cell carcinoma antigens SerpinB3/B4. Nat Commun. 2014;5:3729.
  • Kato H. Expression and function of squamous cell carcinoma antigen. Anticancer Res. 1996;16:2149–2154.
  • Pontisso P, Calabrese F, Benvegnù L, et al. Overexpression of squamous cell carcinoma antigen variants in hepatocellular carcinoma. Br J Cancer. 2004;90:833–837.
  • Turato C, Vitale A, Fasolato S, et al. SERPINB3 is associated with TGF-β1 and cytoplasmic β-catenin expression in hepatocellular carcinomas with poor prognosis. Br J Cancer. 2014;110:2708–2715.
  • Beneduce L, Castaldi F, Marino M, et al. Squamous cell carcinoma antigen-immunoglobulin M complexes as novel biomarkers for hepatocellular carcinoma. Cancer. 2005;103:2558–2565.
  • Buccione D, Fatti G, Gallotta A, et al. Serum SCCA-IgM as a predictor of hepatocellular carcinoma in patients with cirrhosis. O J Gastroenterol. 2012;2:56–61.
  • Pontisso P, Quarta S, Caberlotto C, et al. Progressive increase of SCCA-IgM immune complexes in cirrhotic patients is associated with development of hepatocellular carcinoma . Int J Cancer. 2006;119:735–740.
  • Pozzan C, Cardin R, Piciocchi M, et al. Diagnostic and prognostic role of SCCA-IgM serum levels in hepatocellular carcinoma (HCC). J Gastroenterol Hepatol. 2014;29:1637–1644.
  • Biasiolo A, Chemello L, Quarta S, et al. Monitoring SCCA-IgM complexes in serum predicts liver disease progression in patients with chronic hepatitis. J Viral Hepat. 2008;15:246–249.
  • Giannini EG, Basso M, Bazzica M, et al. Successful antiviral therapy determines a significant decrease in squamous cell carcinoma antigen-associated (SCCA) variants’ serum levels in anti-HCV positive cirrhotic patients. J Viral Hepat. 2010;17:563–598.
  • Martini A, Fattovich G, Guido M, et al. HCV genotype 3 and squamous cell carcinoma antigen (SCCA)-IgM are independently associated with histological features of NASH in HCV-infected patients. J Viral Hepat. 2015;22:800–808.
  • Sarin SK, Kumar M, Lau GK, et al. Asian-Pacific clinical practice guidelines on the management of hepatitis B: a 2015 update. Hepatol Int. 2015;10:1–98.
  • Morisco F, Guarino M, Di Costanzo GG, et al. Circulating SCCA-IgM complex is a useful biomarker to predict the outcome of therapy in HCC patients. J Hepatol. 2015;62:S450.
  • Biasiolo A, Trotta E, Fasolato S, et al. Squamous cell carcinoma antigen-IgM is associated with hepatocellular carcinoma in patients with cirrhosis: a prospective study. Dig Liver Dis. 2016;48:197–202.
  • Fransvea E, Trerotoli P, Sacco R, et al. SCCA-IC serum levels are predictive of clinical response in HCV chronic hepatitis to antiviral therapy: a multicentric prospective study. J Viral Hepat. 2012;19:704–710.
  • Giannelli G, Fransvea E, Trerotoli P, et al. Clinical validation of combined serological biomarkers for improved hepatocellular carcinoma diagnosis in 961 patients. Clin Chim Acta. 2007;383:147–152.
  • Gish RG, Given BD, Lai C-L, et al. Chronic hepatitis B: virology, natural history, current management and a glimpse at future opportunities. Antiviral Res. 2015;121:47–58.
  • Pearlman BL, Traub N. Sustained virological response to antiviral therapy for chronic hepatitis C virus infection: a cure and so much more. Clin Inf Dis. 2011;52:889–900.

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