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Scandinavian Journal of Clinical and Laboratory Investigation Volume 15, 1963 - Issue 5
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Original Article

The Effect of Pkobenecid (P-(DI-N-Propylsulfamyl)-Benzoic Acid) on the Spontaneous Renal Excketion of Biologically Active Metabolites of Thiamine, Riboflavin and Pantothenic Acid

T. Markkanen Department of Medical Microbiology, University of Turku, Turku, Finland
,
P. Toivanen Department of Medical Microbiology, University of Turku, Turku, Finland
,
A. Toivanen Department of Medical Microbiology, University of Turku, Turku, Finland
&
E. Sotaniemi Department of Medical Microbiology, University of Turku, Turku, Finland
Pages 511-516 | Received 28 Apr 1963, Published online: 28 Aug 2009

References

  • Haugen H. N. Renal thiamine excretion in the dog; influence of parenteral administration of glucose. Sand. J. clin. Lab. Invest. 1961; 13: 61
  • Burstein M., Guinand A. The renal excretion of thiamine during administration of Probenecid (p-(di-n-propyl. sulfamyl)-benzoic acid. Ibid. 1961; 13: 661
  • Horwitt M. K. The Vitamins. 1954; Vol. III: 392
  • Iacono J. M., Johnson B. C. Thiamine metabolism of thiazol-2-C14-thiamine in rat. J. Amer. chem. Soc. 1957; 79: 6321
  • Malnic G., Silva A. C., De Angelis R. C., Gomes Z. J. Renal excretion of thiamine by the dog. Amer. J. Physiol. 1960; 198: 1274
  • Da Silva A. C. Simultaneous excretion of thiamine and thiamine phosphates by the dog. Ibid. 1962; 202: 1109
  • Markkanen T. Studies on the urinary excretion of thiamine, riboflavin, nicotinic acid, pantothenic acid and biotin in achlorhydria and after partial gastrectomy. Acta med. sand. 1960; 169
  • Mickelsen O., Caster W. O., Keys A. A statistical evaluation of the thiamine and pyramin excretions of normal young men on controlled intakes of thiamine. J. biol. Chem. 1947; 168: 415
  • Pearson N. N. Biochemical appraisal of nutritional status in man. Amer. J. clin. Nutr. 1962; 11: 462
  • Rennick B. R. The renal tubular excretion of choline and thiamine in the chicken. J. Pharmacol. 1958; 122: 449
  • Volle R. L., Green R. E., Peters L., Handschumacher R. E., Welch A. D. Renal tubular excretion studies with pyrimidine derivatives and analogs. J. Pharmacol. exp. Ther. 1962; 136: 353
  • Ziporin Z. Z., Beier E., Holland D. C., Bier-Man E. L. A method for determining the metabolites of thiamine in urine. Analyt. Bio-chem. 1962; 3: 1

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