22
Views
6
CrossRef citations to date
0
Altmetric
Research Article

Red blood cell rigidification during cyclosporin therapy: a possible early warning signal for adverse reactions

, , &
Pages 617-624 | Published online: 08 Jul 2009

REFERENCES

  • Hess AD, Tutschka PJ. Effect of cyclosporin A on human lymphocyte response in vitro (1). J Immunol 1980; 124: 2601 — 8.
  • Faulds D, Goa KL, Benfield P. Cyclosporin. A review of its pharmacodynamic and pharmacoki-netic properties and therapeutic use in immunore-gulary disorders. Drugs 1993; 45: 953 — 1040.
  • Laupacis A. Complications of cyclosporine therapy; a comparison to azathioprine. Transplant Proc 1983; 15: 2748 — 53.
  • Adu D, Turney J, Michael J, McMaster P. Hyper-kalaemia in cyclosporine treated renal allograft recipients. Lancet 1983; ii: 370 — 2.
  • Thiel G. Experimental cyclosporine A nephrotoxi-city: a summary of the International Workshop (Basle, April 24 — 26, 1985). Clin Nephrol 1986; 25 Supp. 1: S204— 10.
  • Myers BD. Cyclosporine nephrotoxity. Kidney Int 1986; 30: 964–74.
  • Neild GH, Reuben R, Hartley RB, Cameron JS. Glomerular thrombi in renal allografts associated with cyclosporin therapy. J Clin Pathol 1985; 38: 253 — 8.
  • Vanrenterghem Y, Lerut T, Roels L, Gruwel J, Michielsen P, Gresele P, et al. Thromboem-bolic complications and hemostatic changes in cyclosporin-treated cadaveric kidney allograft recipients. Lancet 1985; i: 999 — 1002.
  • Besarab A, Jarell BE, Hirsch S, Carabasi RA. Use of the isolated perfused kidney model to assess the acute pharmalogic effects of cyclosporine and its vehicle, cremophor EL. Transplantation 1987; 44: 195— 201.
  • Luke DR, Kasiske BL, Matzke GR, Keane WF. Effects of cyclosporine on the isolated perfused rat kidney. Transplantation 1987; 43: 785 — 99.
  • ICSH Expert Panel on Blood Rheology. Guidelines for measurement of blood viscosity and erythrocyte deformability. Clin Hemorheol 1986; 6: 439 — 53.
  • Statibli M, Stone PCW, Straub PW, Stuart J. Eva-luation of methods for measuring erythrocyte deformability. Clin Hemorheol 1986; 6: 589 —602.
  • Hardeman MR, Goedhart PT, Dobbe JGG, Lettinga KP. Laser-assisted optical rotational cell analyser (L.O.R.C.A.). 1. A new instrument for measurement of various structural hemorheologi-cal parameters. Clin Hemorheol 1994; 14: 605— 18.
  • Schut NH, Hardeman MR, Wilmink JM. Decrease of erythrocyte deformabillty in cyclosporin treated renal transplant patients; correction with fish as well as corn oil. Transpl Int 1992; 5 Suppl 1: S536 — 8.
  • Milner W, Herrmann B. Cyclosporin for psoriasis. N Engl J Med 1979; 301: 555.
  • Agarwal RP, McPherson RA, Threatte GA. Evi-dence of a cyclosporine binding protein in human erythrocytes. Transplantation 1986; 42: 627 — 32.
  • Hardeman MR, de Rie MA, Schut NH, Wilmink JM. Impaired erythrocyte deformability in psoria-sis patients after treatment with cyclosporin. 7th Eur Conf on Clin Hemorheol, Southampton, 1991. Abstract: Clin Hemorheol 1991; 11: 784.
  • Sentfirk UK, Ceylan H, Baskurt OK. Effect of cyclosporin A on red cell deformability. 7th Eur Conf on Clin Hemorheol, Southampton, 1991. Abstract: Clin Hemorheol 1991; 11: 784.
  • Witkamp L, Meinardl MMHM, Bossuyt PMM, van de Kerkhof PCM, Arnold WP, De Hoop D, et al. A multicentre evaluation of the guidelines for the use of cyclosporine A in severe psoriasis. J Eur Acad Dermatol Venereol 1996; 7: 49–58.
  • Akagi H, Reynolds A, Hjielm M. Cyclosporin A and its metabolites, distribution in blood and tis-sues. J Int Med Res 1991; 19: 1–10.
  • Hardeman MR, Goedhart PT, Schut NH. Laser assisted optical rotational cell analyser (L.O.R.C.A.); II. Red blood cell deformability; elongation index versus cell transit time. Clin Hemorheol 1994; 14: 619–30.
  • Mason J. Renal side-effects of cyclosporin A. Br J Dermatol 1990; 122 Suppl 36: 71–7.
  • Myers BD, Ross J, Newton L, Luetscher J, Perlroth M. Cyclosporine-associated chronic nephropathy. N Engl J Med 1984; 311: 699–705.
  • Fogo A, Hakim RC, Sugiura M, Inagami T, Kon V. Severe endothelial injury in a renal transplant patient receiving cyclosporine. Transplantation 1990; 49: 1190–2.
  • Torras J, Valles J, Sanchez J, Sabate I, Seron D, Carrera M, et al. Prevention of experimental cyclosporine nephrotoxicity by dietary supplemen-tation with LSL 90202: a lysine salt of eicosapen-taenoic acid. Nephron 1994; 67: 66–72.
  • Smith SR, Kubacki VB, Rakhit A, Martin LL, Schafer AV, Jasani MK, et al. Chronic thrombox-ane synthase inhibition with CGS 12970 in human cyclosporine nephrotoxicity. Transplantation 1993; 56: 1422–6.
  • Voss BL, Hamilton KH, Samara ENS, McKee PA. Cyclosporine suppression of endothelial prostacy-clin generation. Transplantation 1988; 45: 793–6.
  • Nield GH, Rocchi G, Imberti L, Fumagalli F, Brown Z, Remuzzi G, Williams DG. Effect of cyclosporin A on prostacyclin synthesis by vascular tissue. Thromb Res 1983; 32: 373–9.
  • Homan van der Heide JJ, Bib o HJG, Tegzess AM, Donker AJM. The effects of dietary supplementa-tion with fish oil on renal function in cyclospor- Me-treatedrenaltransplantrecipients.Transplantation 1990; 49: 523–7.
  • Yoa RG, Corda C, Rapin JR, Santona L, Goudonnet H, Rifle G, et al. Hemorheological benefits of omega-3 polyunsaturated fatty acids on erythrocyte deformability in renal transplanted patients. Clin Hemorheol 1994; 14: 663–75.
  • Schut NH, Bib o HIG, Popp-Snijders C, Goedhart PT, Wilmink JM. Erythrocyte deformability, endothelin levels and renal function in cyclo-sporin-treated renal transplant recipients: effects of intervention with fish oil and corn oil. Scand Clin Lab Invest 1993; 53: 499–506.
  • Harris KP, Jenkins D, Walls J. Nonsteroidal antiin-flammatory drugs and cyclosporin. A potentially serious adverse interaction. Transplantation 1988; 46: 598–9.
  • Mokken FCH, Kedaria M, Henny CHP, Hardeman MR, Gelb AW. The clinical importance of erythrocyte deformability. A hemorheological parameter. Ann Hematol 1992; 64: 113–22.
  • Jandl JH, Greenberg MS, Yonernoto RH, Castle WB. Clinical determination of sites of red cell sequestration in hemolytic anemias. J Clin Invest 1956; 35: 842–6.
  • Nielsen OJ, Mandrup-Poulsen T, Nerup J. Defi-ciency of erythropoietin is not responsible for the anemia associated with cyclosporin treatment of insulin-dependant diabetis mellitus. J Int Med 1993; 233: 471–5.
  • McGrath LT, Treacy R, McClean E, Brown JH. Oxidative stress in cyclosporin and azathioprine treated renal transplant patients. Clin Chim Acta 1997; 264: 1–12.
  • Wang C, Salahudeen AK. Cyclosporin nephrotoxi-city: attenuation by an antioxidant-inhibitor of lipid peroxidation in vitro and in vivo. Transplanta-tion 1994; 58: 940–6.
  • Phair PG, Powell HR, McCredie DA. Lipid abnormalities in red blood cell and plasma phos-pholipids in cyclosporine-treated heart transplant recipients. Transpl Proc 1994; 26: 3722–6.
  • Palinski W, Torsellini A, Doni L. Influence of pla-telet activation on erythrocyte deformability. Thromb Haemost 1983; 49: 84–6.
  • Kovacs IB, O'Grady J. Prostacyclin increases filter-ability of normal and rigidified human red blood cells in vitro. Agents Actions 1984; 14: 306–10.
  • Belch JJF, McLaren M, Anderson J, et al. Increased prostacyclin metabolites and decreased red cell deformability in patients with systemic sclerosis and Raynaud's syndrome. Prostaglandins Leukot Essent Fatty Acids 1985; 17: 1–9.
  • Sipes SL, Weiner CP, Gellhaus TM, Goodspeed JD. Effects of magnesium sulfate infusion upon plasma prostaglandins in preeclampsia and preterm labor. Hypertens Pregn 1994; 13: 293–302.
  • Nozue T, Kobayashi A, Kodama T, Uemasu F, Endoh H, Sako H, Takagi Y. Pathogenesis of cyclosporin-induced hypomagnesia. J Pediatr 1992; 120: 638–40.
  • June CH, Thompson CB, Kennedy MS, Nims J, Thomas ED. Profound hypomagnesemia and renal magnesium wasting associated with the use of cyclosporin for marrow transplantation. Trans-plantation 1985; 39: 620–4.
  • Al-Khursani I, Thomas TH, Harrison K, Wilkinson R. Reduced erythrocyte and leukocyte magnesium is associated with cyclosporin treat-ment and hypertension in renal transplant patients. Nephrol Dial Transpl 1992; 7: 251–5.
  • Dondorp AM, Angus BJ, Hardeman MR, Chotivanich KT, Silamut K, Ruangveerayuth R, et al. Prognostic significance of reduced red blood cell deformability in severe falciparum malaria. Am J Trop Med Hyg 1997; 57: 507–11.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.