Neurohumoral fluid regulation in chronic liver disease

REFERENCES

• Lieberman FL, Denison EK, Reynolds TB. The relationship of plasma volume, portal hyperten-sion, ascites, and renal sodium retention in cirrho-sis. The overflow theory of ascites formation. Ann NY Acad Sci 1970; 170: 202— 12.
   Google Scholar
• Schrier RW, Arroyo V, Bernardi M, Epstein M, Henriksen JH, Rodés J. Peripheral artery vasodi-latation hypothesis: a proposal for the initiation of renal sodium and water retention in cirrhosis. Hepatology 1988; 5: 1151 — 7.
   Google Scholar
• Schrier RW, Niederberger M, Weigert A, Gines P. Peripheral arterial vasodilatation: determinant of functional spectrum of cirrhosis. Sem Liver Dis 1994; 14: 14–22.
   PubMed Web of Science ®Google Scholar
• Arroyo V, Gines P. Arteriolar vasodilatation and the pathogenesis of the hyperdynamic circulation and renal sodium and water retention in cirrhosis. Gastroenterology 1992; 102: 1077–9.
   PubMed Web of Science ®Google Scholar
• Vallance P, Moncada S. Hyperdynamic circula-tion in cirrhosis: a role for nitric oxide? Lancet 1991; 337: 776–8.
   PubMed Web of Science ®Google Scholar
• Groszmann RJ. Hyperdynamic circulation of liver disease 40 years later: pathophysiology and clinical consequences. Hepatology 1994; 20: 1359 — 63.
   PubMed Web of Science ®Google Scholar
• Gupta S, Morgan TR, Gordan GS. Calcitonin gene-related peptide in hepatorenal syndrome. J Clin Gastroenterol 1992; 14: 122 — 6.
   Google Scholar
• Moore K, Wendon J, Frazer M, Karani J, Williams R, Badr K. Plasma endothelin immuno-reactivity in liver disease and the hepatorenal syndrome. N Engl J Med 1992; 327: 1774 — 8.
   PubMed Web of Science ®Google Scholar
• Lemoine 0, Soupison T, Sogni P, Marchant A, Moreau R, Hadengue A, et al. Plasma endotoxin and tumor necrosis factor-alpha in the hyperki-netic state of cirrhosis. J Hepatol 1995; 23: 391 — 5.
   Google Scholar
• Wong F, Blendis L. Natriuretic peptides: are these new links in the hepatorenal connections? Gut 1997; 40: 151 — 2.
   PubMed Web of Science ®Google Scholar
• Fernandez-Rodriguez CM, Prieto J, Quiroga J, Zozoya JM, Andrade A, Nunez M, et al. Plasma levels of substance P in liver cirrhosis: relationship to the activation of vasopressor systems and urinary sodium excretion. Hepatology 1995; 21: 35–40.
   Google Scholar
• Moore K, Ward PS, Taylor GW, Williams R. Systemic and renal production of troboxane A2 and prostacyclin in decompensatd liver disease and hepatorenal syndrome. Gastroenterology 1991; 100: 1069–77.
   PubMed Web of Science ®Google Scholar
• Sieber CC, Lopez-Talavera JC, Groszmann RJ. Role of nitric oxide in the in vitro splanchnic vascular hyporeactivity in ascitic cirrhotic rats. Gastroenterology 1993; 104: 1750–4.
   PubMed Web of Science ®Google Scholar
• Pizcueta P, Pique JM, Fernandez M, Bosch J, Rodes J, Whittle BJR, et al. Modulation of the hyperdynamic circulation of cirrhotic rats by nitric oxide inhibition. Gastroenterology 1992; 103: 1909— 15.
   PubMed Web of Science ®Google Scholar
• Sieber CC, Groszmann RJ. Nitric oxide mediates hyporeactivity to vasopressors in mesenteric ves-sels of portal hypertensive rats. Gastroenterology 1992; 103: 235–9.
   PubMed Web of Science ®Google Scholar
• Karatapanis S, Mccormick PA, Kakad S, Chin JKT, Islam M, Jeremy J, et al. Alteration in vascular reactivity in isolated aortic rings from portal vein-constricted rats. Hepatology 1994; 20: 1516–21.
   PubMed Web of Science ®Google Scholar
• Sogni P, Moreau R, Ohsuga M, Cailmail S, Oberti F, Hadengue A, et al. Evidence for normal nitric oxide mediated vasodilator tone in conscious rats with cirrhosis. Hepatology 1992; 16: 980 — 3.
   PubMed Web of Science ®Google Scholar
• Jones AL, Bangash IH, Bouchier IAD, Hayes PC. Portal and systemic haemodynamic action of N-acetylcysteine in patients with stable cirrhosis. Gut 1994; 35: 1290 — 3.
   PubMed Web of Science ®Google Scholar
• Lee F-Y, Colombato LA, Albillos A, Groszmann RJ. N-nitro-L-arginine administration corrects peripheral vasodilatation and systemic capillary hypotension and ameliorates plasma volume expansion and sodium retention in portal hyper-tensive rats. Hepatology 1993; 17: 84–90.
   Google Scholar
• Niederberger M, Gines P, Martin PY, Tsai P, Morris K, McMurtry I, etal. Comparison of vascular nitric oxide production and systemic hemodynamics in cirrhosis versus prehepatic portal hypertension in rats. Hepatology 1996; 24: 947 — 51.
   Google Scholar
• Kakumitsu S, Shijo H, Yokoyama M, Kim T, Akiyoshi N, Ota K, et al. Effects of L-arginine on the systemic, mesenteric, and hepatic circula-tion in patients with cirrhosis. Hepatology 1998; 27: 377 — 82.
   PubMed Web of Science ®Google Scholar
• Söderman C, Leone A, Furst V, Persson MG. Endogenous nitric oxide in exhaled air from patients with liver cirrhosis. Scand J Gastro-enterol 1997; 32: 591 —7.
   Google Scholar
• Rolla G, Brussino L, Colagrande P, Dutto L, Polizzi S, Scappaticci E, etal. Exhaled nitric oxide and oxygenation abnormalities in hepatic cirrho-sis. Hepatology 1997; 26: 842–7.
   Google Scholar
• Calver A, Harris A, Maxwell JD, Vallance P. Effect of local inhibition of nitric oxide synthesis on forearm blood now and dorsal hand vein size in patients with alcoholic cirrhosis. Clin Sci 1994; 86: 203 — 8.
   Google Scholar
• Ryan J, Jennings G, Dudley F, Chindusting J. Smooth muscle-derived nitric oxide is elevated in isolated forearm veins in human alcoholic cirrhosis. Clin Sci 1996; 91: 23 — 8.
   Google Scholar
• Fernandez M, Garcia-Pagan JC, Casadevall M, Bernadich C, Piera C, Whittle BJR, etal. Evidence against a role for inducible nitric oxide synthase in the hyperdynamic circulation of portal-hyperten-sive rats. Gastroenterology 1995; 108: 1487–95.
   PubMed Web of Science ®Google Scholar
• Kanwar S, Kubes P, Tepperman BL, Lee SS. Nitric oxide synthase activity in portal-hyperten-sive and cirrhotic rats. J Hepatol 1996; 25: 85–9.
   PubMed Web of Science ®Google Scholar
• Bomzon A, Blendis LM. The nitric oxide hypoth-esis and the hyperdynamic circulation in cirrhosis. Hepatology 1994; 20: 1343–50.
   PubMed Web of Science ®Google Scholar
• Campillo B, Chabrier PE, Pelle G, Sediame S, Atlan G, Fouet P, et al. Inhibition of nitric oxide synthesis in the forearm arterial bed of patients with advanced cirrhosis. Hepatology 1995; 22: 1423–9.
   PubMed Web of Science ®Google Scholar
• O'Halloran DJ, Bloom SR. Calcitonin gene-related peptide. A major neuropeptide and the most powerful vasodilator known. Br Med J 1991; 302: 739–40.
   Google Scholar
• Bendtsen F, Schiffer S, Henriksen JH. Increased circulating calcitonin gene-related peptide (CGRP) in cirrhosis. J Hepatol 1991; 12: 118–23.
   Google Scholar
• McNicol PL, Liu G, Shulkes A, Hardy KJ, Jones RM. Vasoactive intestinal peptide and calcitonin gene-related peptide levels and hemodynamics during human liver transplantation. Transplant Proc 1993; 25: 1830–1.
   Google Scholar
• Moller S, Becker U, Schifter S, Abrahamsen J, Henriksen JH. Effect of oxygen inhalation on sys-temic, central, and splanchnic haemodynamics in cirrhosis. J Hepatol 1996; 25: 316–28.
   Google Scholar
• Moller S, Bendtsen F, Schiffer S, Henriksen JH. Relation of calcitonin gene-related peptide to systemic vasodilatation and central hypovolaemia in cirrhosis. Scand J Gastroenterol 1996; 31: 928–33.
   PubMed Web of Science ®Google Scholar
• Hon i N, Okanoue T, Sawa Y, Kashima K. Role of calcitonin gene-related peptide in the vascular system on the development of the hyperdynamic circulation in conscious cirrhotic rats. J Hepatol 1997; 26: 1111–19.
   PubMed Web of Science ®Google Scholar
• Richards AM, Nicholls MG, Lewis L, Lainchbury JG. Adrenomedullin. Clin Sci 1996; 91: 3–16.
   PubMed Web of Science ®Google Scholar
• Cheung B, Leung R. Elevated plasma levels of human adrenomedullin in cardiovascular, respira-tory, hepatic and renal disorders. Clin Sci 1997; 92: 59–62.
   Google Scholar
• Guevara M, Gines P, Jimenez W, Sort P, Fernandezesparrach G, Escorsell A, et al. Increased adrenomedullin levels in cirrhosis: rela-tionship with hemodynamic abnormalities and vasoconstrictor systems. Gastroenterology 1998; 114: 336–43.
   PubMed Web of Science ®Google Scholar
• Groszmann RJ. Vasodilatation and hyperdynamic circulatory state in chronic liver disease. In: Bosch J, Groszmann RJ, editors. Portal hyper-tension. Pathophysiology and treatment. Oxford: Blackwell 1994: 17–26.
   Google Scholar
• McDonagh TA, Robb SD, Murdoch DR, Morton JJ, Ford I, Morrison CE, etal. Biochemical detec-tion of left-ventricular systolic dysfunction. Lancet 1998; 351: 9–13.
   Google Scholar
• Bernardi M, Trevisani F, Gasbarrini A, Gasbarrini G. Hepatorenal disorders. Role of the renin - angiotensin - aldosterone system. Sem Liver Dis 1994; 14: 23–34.
   Google Scholar
• Henriksen JH, Ring-Larsen H. Hepatorenal dis-orders: role of the sympathetic nervous system. Sem Liver Dis 1994; 14: 35–43.
   PubMed Web of Science ®Google Scholar
• Arroyo V, Claria J, Salo J, Jimenez W. Antidiuretic hormone and the pathogenesis of water retention in cirrhosis with ascites. Sem Liver Dis 1994; 14: 44–58.
   PubMed Web of Science ®Google Scholar
• Moller S, Henriksen JH. Endothelins in chronic liver disease. Scand J Clin Lab Invest 1996; 56: 481–90.
   PubMed Web of Science ®Google Scholar
• Rocky D. The cellular pathogenesis of portal hypertension: stellate cell contractility, endothe-lin, and nitric oxide. Hepatology 1997; 25: 2–5.
   PubMed Web of Science ®Google Scholar
• Lee SS. Cardiac abnormalities in liver cirrhosis. West J Med 1989; 151: 530–5.
   PubMedGoogle Scholar
• Ma Z, Lee SS. Cirrhotic cardiomyopathy: getting to the heart of the matter. Hepatology 1996; 24: 451–9.
   PubMed Web of Science ®Google Scholar
• Henriksen JH, Bendtsen F, Sorensen TIA, Stadeager C, Ring-Larsen H. Reduced central blood volume in cirrhosis. Gastroenterology 1989; 97: 1506–13.
   PubMed Web of Science ®Google Scholar
• Dudley FJ. Pathophysiology of sodium retention in cirrhosis. In: Bosch J, Groszmann RJ, editors. Portal hypertension. Pathophysiology and treat-ment. Oxford: Blackwell, 1994: 54–71.
   Google Scholar
• Bomzon A, Binah 0, Blendis LM. Hypotension in experimental cirrhosis-Is loss of vascular responsiveness to norepinephrine the cause of hypotension in chronic bile-duct-ligated dogs. J Hepatol 1993; 17: 116–23.
   Google Scholar
• Bernardi M, Rubboli A, Trevisani F, Cancellieri C, Ligabue A, Baradini M, etal. Reduced cardio-vascular responsiveness to exercise-induced sym-pathoadrenergic stimulation in patients with cirrhosis. J Hepatol 1991; 12: 207–16.
   Google Scholar
• MacGilchrist AJ, Sumner D, Reid JL. Impaired pressor reactivity in cirrhosis: evidence for a peripheral vascular defect. Hepatology 1991; 13: 689–94.
   Google Scholar
• Dillon JF, Plevris JN, Nolan J, Ewing DJ, Neilson JMM, Bouchier IAD, etal. Autonomic function in cirrhosis assessed by cardiovascular reflex tests and 24-hour heart rate variability. Am J Gastro-enterol 1994; 89: 1544–7.
   Google Scholar
• Murray BM, Paller MS. Decreased pressor reac-tivity to angiotensin II in cirrhotic rats. Evidence for a post-receptor defect in angiotensin action. Circ Res 1985; 57: 424–31.
   Google Scholar
• Polio J, Sieber CC, Lerner E, Groszmann RJ. Cardiovascular hyporesponsiveness to norepine-phrine, propranolol and nitroglycerin in portal-hypertensive and aged rats. Hepatology 1993; 18: 128–36.
   PubMed Web of Science ®Google Scholar
• Gerbes AL, Remien J, Jiingst D, Sauerbruch T, Paumgartner G. Evidence for down-regulation of beta-2-adrenoceptors in cirrhotic patients with severe ascites. Lancet 1986; 1: 1409–11.
   Google Scholar
• Bierbrier GS, Adams PC, Feldman RD. Vascular alpha-adrenergic responsiveness is reduced in cir-rhosis. Clin Pharmacol Ther 1994; 56: 668–71.
   Google Scholar
• Moreau R, Komaichi H, Kistetter P, Ohsuga M, Cailmail S, Lebrec D. Altered control of vascular tone by adenosine triphosphate-sensitive potassium channels in rats with cirrhosis. Gastro-enterology 1994; 106: 1016–23.
   PubMed Web of Science ®Google Scholar
• Chu CJ, Lee FY, Wang SS, Lu RH, Tsai YT, Lin HC, et al. Hyperdynamic circulation of cirrhotic rats with ascites: role of endotoxin, tumour necro-sis factor-alpha and nitric oxide. Clin Sci 1997; 93: 216–25.
   Google Scholar
• Lopez-Talavera JC, Merrill WW, Groszmann RJ. Tumor necrosis factor alpha: a major contributor to the hyperdynamic circulation in prehepatic por-tal-hypertensive rats. Gastroenterology 1995; 108: 761–7.
   Google Scholar
• Moreau R, Lebrec D. Endogenous factors involved in the control of arterial tone in cirrhosis. J Hepatol 1995; 22: 370–6.
   PubMed Web of Science ®Google Scholar
• Hendrickse MT, Thuluvath PJ, Triger DR. Nat-ural history of autonomic neuropathy in chronic liver disease. Lancet 1992; 339: 1462–4.
   Google Scholar
• Laffi G, Lagi A, Cipriani M, Barletta G, Bernardi L, Fattorini L, et al. Impaired cardiovascular autonomic response to passive tilting in cirrhosis with ascites. Hepatology 1996; 24: 1063–7.
   PubMed Web of Science ®Google Scholar
• Oliver MI, Miralles R, Rubiesprat J, Navarro X, Espadaler JM, Sola R, et al. Autonomic dysfunc-tion in patients with non-alcoholic chronic liver disease. J Hepatol 1997; 26: 1242–8.
   PubMed Web of Science ®Google Scholar
• Fleckenstein JF, Frank SM, Thuluvath PJ. Presence of autonomic neuropathy is a poor prognostic indicator in patients with advanced liver disease. Hepatology 1996; 23: 471–5.
   Google Scholar
• Mohammed R, Forsey PR, Davies MK, Neuberger JM. Effect of liver transplantation on QT interval prolongation and autonomic dysfunc-tion in end-stage liver disease. Hepatology 1996; 23: 1128–34.
   PubMed Web of Science ®Google Scholar
• Hendrickse MT, Triger DR. Vagal dysfunction and impaired urinary sodium and water excre-tion in cirrhosis. Am J Gastroenterol 1994; 89: 750–7.
   PubMed Web of Science ®Google Scholar
• Isobe H, Sakai H, Sakamoto S, Nawata H. Decreased variation of electrocardiographic R - R interval in patients with liver cirrhosis. J Gastroenterol Hepatol 1994; 9: 232–5.
   PubMed Web of Science ®Google Scholar
• Laffi G, Barletta G, Lavilla G, Delbene R, Riccardi D, Ticali P, et al. Altered cardiovascular responsiveness to active tilting in nonalcoholic cirrhosis. Gastroenterology 1997; 113: 891–8.
   PubMed Web of Science ®Google Scholar
• Iwao T, Toyonaga A, Ikegami M, Sumino M, Oho K, Sakaki M, etal. Reduced portosystemic hemo-dynamic responsiveness after orthostasis in patients with cirrhosis. Dig Dis Sci 1993; 38: 1251–8.
   Google Scholar
• Ryan J, Sudhir K, Jennings G, Esler M, Dudley F. Impaired reactivity of the peripheral vasculature to pressor agents in alcoholic cirrhosis. Gastro-enterology 1993; 105: 1167–72.
   Google Scholar
• Dillon JF, Nolan J, Thomas H, Williams BC, Neilson JMM, Bouchier IAD, et al. The correc-tion of autonomic dysfunction in cirrhosis by captopril. J Hepatol 1997; 26: 331–5.
   PubMed Web of Science ®Google Scholar
• Lazzeri C, Lavilla G, Laffi G, Vecchiarino S, Gambilonghi F, Gentilini P, et al. Autonomic regulation of heart rate and QT interval in non-alcoholic cirrhosis with ascites. Digestion 1997; 58: 580–6.
   PubMed Web of Science ®Google Scholar
• Bernardi M, Calandra S, Colantoni A, Trevisani F, Raimondo ML, Sica G, et al. Q - T interval prolongation in cirrhosis: prevalence, relationship with severity, and etiology of the disease and pos-sible pathogenetic factors. Hepatology 1998; 27: 28–34.
   PubMed Web of Science ®Google Scholar
• Lee SS, Pak JM, Medlicott SM, Bomzon A. Vaso-dilatory responses of isolated arteries of cirrhotic rats. Clin Sci 1995; 89: 227–32.
   Google Scholar
• Jaue DN, Ma ZH, Lee SS. Cardiac muscarinic receptor function in rats with cirrhotic cardio-myopathy. Hepatology 1997; 25: 1361–5.
   Google Scholar
• Rowell LB. Human cardiovascular control. Oxford: Oxford University Press, 1993.
   Google Scholar
• Kumada M, Terui N, Kuwaki T. Arterial baroreceptor reflex: its central and peripheral neural mechanisms. Progr Neurobiol 1990; 35: 331–61.
   Google Scholar
• Schrier RW, Howard RL. Unifying hypothesis of sodium and water regulation in health and dis-ease. Hypertension 1991; 18 Suppl III: 164–8.
   Google Scholar
• Henriksen JH, Ring-Larsen H, Christensen NJ. Sympathetic nervous regulation in patients with cirrhosis: pathogenesis of fluid retention and for-mation of ascites. Can J Gastroenterol 1991; 5(3): 103–11.
   Google Scholar
• Kirstetter P, Moreau R, Soupison T, Cailmail S, Hartleb M, Lebrec D. Role of sympathetic cardi-ovascular tone in control of arterial pressure in rats with cirrhosis. Liver 1996; 16: 263–6.
   PubMedGoogle Scholar
• Moller S, Emmeluth C, Henriksen JH. Elevated circulating plasma endothelin - 1 concentrations in cirrhosis. J Hepatol 1993; 19: 285–90.
   Google Scholar
• Moller S, Wiinberg N, Henriksen JH. Noninvasive 24-hour ambulatory arterial blood pressure mon-itoring in cirrhosis. Hepatology 1995; 22: 88–95.
   Google Scholar
• Pasqualetti P, Festuccia V, Collacciani A, Acitelli P, Casale R. Circadian rhythm of arginine vaso-pressin in hepatorenal syndrome. Nephron 1998; 78: 33–7.
   Google Scholar
• Trevisani F, Colantoni A, Gerbes AL, Gülberg V, Sica G, Caraceni P, et al. Daily profile of plasma endothelin-1 and -3 in pre-ascitic cirrhosis: relationships with the arterial pressure and renal function. J Hepatol 1997; 26: 808–15.
   Google Scholar
• Moller S, Christensen E, Henriksen JH. Con-tinuous blood pressure monitoring in cirrhosis: relations to systemic and splanchnic haemo-dynamics. J Hepatol 1997; 27: 284–94.
   Google Scholar
• Moller S, Bendtsen F, Christensen E, Henriksen JH. Prognostic variables in patients with cirrhosis and oesophageal varices without prior bleeding. J Hepatol 1994; 21: 940–6.
   PubMed Web of Science ®Google Scholar
• Moller S, Sondergaard L, Mogelvang J, Henriksen 0, Henriksen JH. Decreased right heart blood volume determined by magnetic reso-nance imaging: evidence of central underfilling in cirrhosis. Hepatology 1995; 22: 472–8.
   Google Scholar
• Moller S. Systemic haemodynamics in cirrhosis and portal hypertension with focus on vasoactive substances and prognosis. Dan Med Bull 1998; 45: 1–14.
   PubMed Web of Science ®Google Scholar
• Moller S, Bendtsen F, Henriksen JH. Effect of volume expansion on systemic hemodynamics and central and arterial blood volume in cirrhosis. Gastroenterology 1995; 109: 1917 — 25.
   Google Scholar
• Colombato LA, Albillos A, Groszmann J. The role of central blood volume in the development of sodium retention in portal hypertensive rats. Gastroenterology 1996; 110: 193 — 8.
   Google Scholar
• Laffi G, La Villa G, Gentilini P. Pathogenesis and management of the hepatorenal syndrome. Sem Liver Dis 1994; 14: 1 — 81.
   Google Scholar
• Henriksen JH, Bendtsen F, Gerbes AL, Christensen NJ, Ring-Larsen H, Sorensen TIA. Estimated central blood volume in cirrhosis—relationship to sympathetic nervous activity, beta-adrenergic blockade and atrial natriuretic factor. Hepatology 1992; 16: 1163 — 70.
   Google Scholar
• Wong F, Liu P, Blendis L. Assessment of central blood volume in cirrhosis by radionuclide angiography: What does it really mean? Reply. Hepatology 1994; 20: 1654 — 6.
   Google Scholar
• Blendis LM. Circulation in liver disease. Trans-plant Proc 1993; 25: 1741 — 3.
   PubMed Web of Science ®Google Scholar
• Gaudin C, Braillon A, Poo JL, Moreau R, Hadengue A, Lebrec D. Regional sympathetic activity, severity of liver disease and hemo-dynamics in patients with cirrhosis. J Hepatol 1991; 13: 161 — 8.
   PubMed Web of Science ®Google Scholar
• Brinch K, Moller S, Bendtsen F, Henriksen JH. Effect of albumin-induced volume expansion on central- and non-central blood volumes in cirrhosis. J Hepatol 1997; 26 Suppl 1: 99.
   Google Scholar
• Salerno F, DelBo A, Maggi A, Marabini M, Maffi M, Borroni GM, et al. Vasopressin release and water metabolism in patients with cirrhosis. J Hepatol 1994; 21: 822 — 30.
   PubMed Web of Science ®Google Scholar
• Henriksen JH, Ring-Larsen H. Ascites formation in liver cirrhosis: the how and the why. Dig Dis Sci 1990; 8: 152–62.
   Google Scholar
• Hayes PC, Cumming AD, Craig KJ, Watson M, Bouchier IAD. Portal and systemic hemo-dynamics and humoral factors in cirrhosis with and without ascites. Am J Gastroenterol 1992; 87: 1433–8.
   Google Scholar
• Henriksen JH, Ring-Larsen H. Raised renal venous pressure: direct cause of renal sodium retention in cirrhosis? Lancet 1988; ii: 8602.
   Google Scholar
• Henriksen JH, Ring-Larsen H. Renal effects of drugs used in the treatment of portal hyperten-sion. Hepatology 1993; 18: 688–95.
   PubMed Web of Science ®Google Scholar
• Nicholls KM, Shapiro MD, Kluge R. Sodium excretion in advanced cirrhosis: effect of expansion of central blood volume and suppression of plasma aldosterone. Hepatology 1986; 82: 709 — 19.
   Google Scholar
• Lenz K, Hörtnagel H, Druml W, Reiter H, Schmid R, Schneeweiss B, et al. Omnipressin in the treatment of functional renal failure in decom-pensated cirrhosis: effects on renal hemodynamics and atrial natriuretic factor. Gastroenterology 1991; 101: 1060–7.
   PubMed Web of Science ®Google Scholar
• Guevara M, Gines P, Fernandez-Esparrach G, Sort P, Salmeron JM, Jimenez W, et al. Reversi-bility of hepatorenal syndrome by prolonged administration of omnipressin and plasma volume expansion. Hepatology 1998; 27: 35–41.
   Google Scholar
• Forrest EH, Bouchier IAD, Hayes PC. Acute effect of low dose theophylline on the circula-tory disturbances of cirrhosis. Gut 1997; 40: 139 — 44.
   Google Scholar
• Haynes WG, Ferro CJ, Okane KPJ, Somerville D, Lomax CC, Webb DJ. Systemic endothelin recep-tor blockade decreases peripheral vascular resis-tance and blood pressure in humans. Circulation 1996; 93: 1860–70.
   PubMed Web of Science ®Google Scholar