Mucosal in Vitro Permeability in the Intestinal Tract of the Pig, the Rat, and Man: Species- and Region-Related Differences

References

• References
   Google Scholar
• Powell D. Barrier function of epithelia. Am J Physiol 1981; 241:G275–88.
   PubMed Web of Science ®Google Scholar
• Travis S, Menzies I. Intestinal permeability: functional assessment and significance. Clin Sci 1992;82:471–88.
   PubMed Web of Science ®Google Scholar
• Hollander D. The intestinal permeability barrier. A hypothesis as to its regulation and involvement in Crohn’s disease. Scand J Gastroenterol 1992;27:721–6.
   Google Scholar
• Sanderson IR, Walker WA. Uptake and transport of macromolecules by the intestine: possible role in clinical disorders. Gastroenterology 1993;104:622–39.
   PubMed Web of Science ®Google Scholar
• Bjarnason I, MacPherson A, Hollander D. Intestinal permeability: an overview. Gastroenterology 1995;108:1566–81.
   Google Scholar
• Meddings JB, Gibbon I. Discrimination of site-specific alteration in gastrointestinal permeability in the rat. Gastroenterology 1998;114:83–92.
   PubMed Web of Science ®Google Scholar
• Pantzar N, Weström BR, Lutz A, Lundin S. Regional small-intestinal permeability in vitro to different-sized dextrans and proteins in the rat. Scand J Gastroenterol 1993;28:205–11.
   PubMed Web of Science ®Google Scholar
• Mynott T, Guandalini S, Raimondi F, Fasano F. Bromelain prevents secretion caused by Vibrio cholerae and Escherichia coli enterotoxins in rabbit ileum in vitro. Gastroenterology 1997; 113:175–84.
   PubMed Web of Science ®Google Scholar
• Schlichting E, Grotmol T, Köhler H, Naess O, Steinbakk M, Lyberg T. Alteration in mucosal morphology and permeability, but no bacterial or endotoxin translocation takes place after intestinal ischemia and early reperfusion in pigs. Shock 1995; 3:116–24.
   Google Scholar
• Kararli TT. Comparison of the gastrointestinal anatomy, physiology, and biochemistry of humans and commonly used laboratory animals. Biopharm Drug Dispos 1995;16:351–80.
   PubMed Web of Science ®Google Scholar
• Taylor AB, Anderson JH. Scanning electron microscope observation of mammalian intestinal villi, intervillus floor and crypt tubulus. Micron 1972;3:430–53.
   Google Scholar
• Watkins PB. The barrier function of CYP3A4 and P-glycoproteins in the small bowel. Adv Drug Deliv Rev 1997;27:161–70.
   PubMed Web of Science ®Google Scholar
• Jerzyk N, Rubas W, Grass GM. Permeability characteristics of various intestinal regions of rabbit, dog, and monkey. Pharm Res 1992;12:1580–6.
   Google Scholar
• Pantzar N, Lundin S, Wester L, Weström BR. Bidirectional small-intestinal permeability in the rat to some common marker molecules in vitro. Scand J Gastroenterol 1994;29:703–9.
   Google Scholar
• Ungell A-L, Nylander S, Bergstrand S, Sjöberg ÅK, Lennernäs H. Membrane transport of drugs in different regions of the intestinal tract of the rat. J Pharm Sci 1998;3:360–6.
   Google Scholar
• Bijlsma PB, Peeters RA, Groot JA, Dekker PR, Taminiau JAJM, Van Der Meer R. Differential in vivo and in vitro intestinal permeability to lactulose and mannitol in animals and humans: a hypothesis. Gastroenterology 1995;108:687–96.
   Google Scholar
• Delahunthy T, Hollander D. A comparison of intestinal permeability between humans and three common laboratory animals. Comp Biochem Physiol 1987;86A:565–7.
   Web of Science ®Google Scholar
• Grass GM, Sweetana SA. In vitro measurement of gastrointestinal tissue permeability using a new diffusion cell. Pharm Res 1988;5:372–6.
   PubMed Web of Science ®Google Scholar
• Laurell CB. Electroimmunoassay. Scand J Clin Lab Invest 1972; 29:21–37.
   Web of Science ®Google Scholar
• Pantzar N, Weström BR, Luts A, Lundin S. Regional small-intestinal permeability in vitro to different-sized dextrans and proteins in the rat. Scand J Gastroenterol 1993;28:205–11.
   PubMed Web of Science ®Google Scholar
• Söderholm JD, Hedman L, Artursson P, Franzen L, Pantzar N, Permert J, et al. Integrity and metabolism of human ileal mucosa in vitro in the Ussing chamber. Acta Physiol Scand 1998;162: 47–56.
   Google Scholar
• Polentarutti B, Peterson AL, Sjöberg ÅK Anderberg EK, Utter L, Ungell AL. Evaluation of viability of excised rat intestinal segments in the Ussing chamber: investigation of morphology, electrical parameters, and permeability characteristics. Pharm Res 1999;16:446–53.
   Google Scholar
• Corbett CL, Isaacs ET, Riley AK, Turnberg LA. Human intestinal ion transport in vitro. Gut 1977;18:136–40.
   PubMed Web of Science ®Google Scholar
• Orlando R, Powell DW, Croom RD, Bergschneider HM, Boucher RC, Knowles MR. Colonic and esophageal transepithelial potential difference in cystic fibrosis. Gastroenterology 1989;96:1041–8.
   PubMed Web of Science ®Google Scholar
• Davies GR, Santa Ana CA, Morawski SG, Fordtran JS. Permeability characteristics of human jejunum, ileum, proximal colon and distal colon: results of potential difference measurements and unidirectional fluxes. Gastroenterology 1982;83:844–50.
   PubMed Web of Science ®Google Scholar
• Rubas W, Jerzyk N, Grass GM. Mechanism of dextran transport across rabbit intestinal tissue and a human colon cell-line (CACO-2). J Drug Targ 1995;3: 15–21.
   Google Scholar
• Menzies IS. Transmucosal passage of inert molecules in health and disease. In: Skadhauge E, Heintze K, editors. Intestinal absorption and secretion. Falk Symposium 36. Lancaster, England: MTP; 1984. p. 527–43.
   Google Scholar
• Lloyd JB. Intestinal permeability to polyethyleneglycol and sugars: are-evaluation. Clin Sci 1998;95:107–10.
   Web of Science ®Google Scholar
• Fordtran JS, Rector FC, Ewton MF, Sofer N, Kinney J. Permeability characteristics of the small intestine. J Clin Invest 1965;44:1935–44.
   PubMed Web of Science ®Google Scholar
• Chadwick VS, Philips SF, Hofman AF. Measurements of intestinal permeability using low molecular weight polyethylene glycols (PEG 400). II. Application to normal and abnormal permeability states in man and animals Gastroenterology 1977; 73:247–51.
   Google Scholar
• Krugliak P, Hollander D, Schlaepfer CC, Nguyen H, Ma TY. Mechanisms and sites of mannitol permeability of small and large intestine in the rat. Dig Dis Sci 1994;39:796–801.
   Google Scholar
• Pantzar N. Characteristics of intestinal permeability to differentsized molecules in the rat [thesis]. Lund, Sweden: Lund University, Dept. of Animal Physiology; 1995.
   Google Scholar
• Debnam ES, Denholm EE, Grimble GK. Acute and chronic exposure of rat intestinal mucosa to dextran promotes SGLTI-mediated glucose transport. Eur J Clin Invest 1998;28:651–8.
   Google Scholar
• Bjarnason I, Smethhurst P, Levi AJ, Peters TJ. Intestinal permeability to 51Cr-EDTA in rats with experimentally induced enteropathy. Gut 1985;26:579–85.
   PubMed Web of Science ®Google Scholar
• Bjarnason I, Peters TJ, Veall N. A persistent defect in intestinal permeability in coelic disease demonstrated by a 51Cr-labelled EDTA absorption test. Lancet 1983;12: 323–5.
   Google Scholar
• Hall EJ, Batt RM. Differential sugar absorption for the assessment of canine intestinal intestinal permeability: the cellobiose/mannitol test in gluten-sensitive enteropathy of Irish setters. Res Vet Sci 1991;51:83–7.
   PubMed Web of Science ®Google Scholar
• Nejdfors P, Wang Q, Ekelund M, Westrom BR, Jansson O, Lindström CL, et al. Increased colonic permeability in patients with ulcerative colitis: an in vitro study. Scand J Gastroenterol 1998;33:749–53.
   Google Scholar