75
Views
48
CrossRef citations to date
0
Altmetric
Research Article

Familial and Sporadic Inflammatory Bowel Disease: Comparison of Clinical Features and Serological Markers in a Genetically Homogeneous Population

Pages 692-698 | Published online: 08 Jul 2009

  • Hugot JP, Laurent-Puig P, Gower-Rousseau C, Oison J, Lee J, Beaugerie L, et al. Mapping of a susceptibility locus for Crohn's disease on chromosome 16. Nature 1996;379:821-3.
  • Satsangi J, Parkes M, Louis E, Hashimoto L, Kato N, Welsh K, et al. Two-stage genome-wide search in inflammatory bowel disease: evidence for susceptibility loci on chromosomes 3, 7 and 12. Nat Genet 1996; 14:199-202.
  • The IBD International Genetics Consortium. International collaboration provides convincing linkage replication in complex disease through analysis of a large pooled data set: Crohn disease and chromosome 16. Am J Hum Genet 2001:68;1165-71.
  • Hampe J, Cuthbert A, Croucher P, Mirza M, Mascheietti S, Fisher S, et al. Association between insertion in NOD2 gene and Crohn's disease in German and British populations. Lancet 2001:357:1925-8.
  • Ogura Y, Bonen D, Inohara N, Nicolae D, Chen F, Ramos R, et al. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 2001:411:603-6.
  • Hugot J-P, Chamaillard M, Zouali H, Lesage S, Cezard L-P, Belaiches J, et al. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 2001:411 : 599-603.
  • Paavola P, Heliö T, Kiuru M, Halme L, Turunen U, Terwillinger J, et al. Genetic analysis in Finnish families with inflammatory bowel disease supports linkage to chromosome 3p21. Eur J Hum Genet 2001:9:328-34.
  • Rioux JD, Silverberg MS, DaIy MJ, Steinhart A, McLeod R, Griffiths A, et al. Genome wide search in Canadian families with inflammatory bowel disease reveals two novel susceptibility loci. Am J Hum Genet 2000;66:1863-70.
  • Lindberg E, Tysk C, Andersso n K, Järnerot G. Smoking and inflammatory bowel disease. A case-control study. Gut 1988;29: 352-7.
  • Sandborn WJ, Tremaine WJ, Offord KP, Lawson GM, Petersen BT, Bans KP, et al. Transdermal nicotine for mildly to moderately active ulcerative colitis. A randomised double-blind, placebo-controlled trial. Ann Intern Med 1997;126:364-71.
  • Cosnes J, Beaugerie L, Carbonnel F, Gendre JP. Smoking cessation and the course of Crohn's disease: an intervention study. Gastroenterology 2001;120:1093-9.
  • Shanahan F, Duerr RH, Rotter JI, Yang H, Sutherland L, McElree C, et al. Neutrophil autoantibodies in ulcerative colitis: familial aggregatio n and genetic heterogeneity. Gastroenterolog y 1992:103:456-61
  • Seibold F, Slametschka D, Gregor M, Weber P. Neutrophil antibodies: a genetic marker in primary sclerosing cholangitis and ulcerative colitis. Gastroenterology 1994;107:532-6.
  • Lee JC, Lennard-Jones JE, Cambridge G. Antineutrophil antibodies in familial inflammatory bowel disease. Gastroenterology 1995:108:428-33.
  • Quintan JF, Sendid B, Reumax D, Duthilleul P, Cortot A, Grandbastien B, et al. Anti-Saccharomyces cerevisiae mannan antibodies combined with antineutrophil cytoplasmic autoantibodies in inflammatory bowel disease; prevalence and diagnostic role. Gut 1998;42:788-91.
  • Sutton CL, Yang H, Li Z, Rotter JI, Targan SR, Braun J. Familial expession of anti-Sacchammyce s cerevisiae mannan antibodies in affected and unaffected relatives of patients with Crohn's disease. Gut 2000;46:58-63.
  • Seibold F, Stich O, Hufhagl R, Kamil S, Scheurlen M. AntiSaccharomyces cerevisiae antibodies in inflammatory bowel disease: a family study. Scand J Gastroenterol 2001 ;36:196-201.
  • Lennard-Jones JE. Classification of inflammatory bowel disease. Scand J Gastroenterol 1989;24 Suppl:2-6.
  • Gasche C, Scholmerich J, Brynskov J, D'Haens G, Hanauer SB, Irvine EJ, et al. A simple classification of Crohn's disease: report of the working party for the world congresse s of gastroenterolog y Vienna 1998. Inflammatory Bowel Diseases 2000;6:8-15.
  • Savige J, Gillis D, Benson E, Davies D, Esnault V, FaIk R. International consensus statement on testing and reporting of antineutrophi 1 cytoplasmic antibodies (ANCA). Am J Clin Pathol 1999:111:507-13.
  • Orholm M, Munkholm P, Langholz E, Nielsen OH, Sorensen A, Binder V. Familial occurrence of inflammatory bowel disease. N Engl J Med 1991;324:84-8.
  • Monsen U, Bernell O, Johansson C, Hellers G. Prevalence of inflammatory bowel disease among relatives of patients with Crohn's disease. Scand J Gastroenterol 1991;26:302-6.
  • Carbonnel F, Macaigne G, Beaugerie L, Gendre JP, Cosnes J. Crohn's disease severity in familial sporadic cases Gut 1999;44: 91-9.
  • Peelers M, Nevens H, Baert F, Hiele M, de Mayer AM, Vlietinck R, et al. Familial aggregation in Crohn's disease: increased ageadjusted risk and concordance in clinical characteristics. Gastroenterology 1996;! 11:597 -603.
  • Satsangi J, Grootscholten C, Holt H, Jewel! D. Clinical patterns of familial inflammatory bowel disease. Gut 1996;38:738-41.
  • Colombel J-F, Grandbastien B, Gower-Rousseau C, Plegat S, Evrard JP, Dupas JL, et al. Clinical characteristics of Crohn's disease in 72 families. Gastroenterolog y 1996;111:604-7.
  • Polito JM, Childs B, Mellits ED, Tokayer AZ, Harris ML, Bayless TM. Crohn's disease: influence of age at diagnosis on site and clinical type of disease. Gastroenterolog y 1996;111: 580-6.
  • Cottone M, Brognola C, Rosselli M, Oliva L, Belloni C, Cipolle C, et al. Relationship between site of disease and familial occurrence in Crohn's disease. Dig Dis Sei 1997;42:129-32.
  • Monsen U, Broström O, Norden val 1 B, Sörstad J, Hellers G. Prevalence of inflammatory bowel disease among relatives of patients with ulcerative colitis. Scand J Gastroenterol 1987;22: 214-8.
  • Lee JCW, Bridger S, McGregor C, Macpherson AJS, LennardJones JE. Why children with inflammatory bowel disease are diagnosed at a younger age than their affected parent. Gut 1999:44:808-11.
  • Yang H, McElree C, Roth M-P, Shanahan F, Targan SR, Rotter JI. Familial empirical risks for inflammatory bowel disease: differences between Jews and non-Jews. Gut 1993;34:517-24.
  • Orholm M, Fonager K, Sorensen T. Risk of ulcerative colitis and Crohn's disease among offspring of patients with chronic inflammatory bowel disease. Am J Gastroenterol 1999;94: 3236-8.
  • Vermeire S, Joossens S, Peelers M, Monsuur F, Marien G, Bossuyt X, et al. Comparative study of ASCA (Anti-Saccharomyces cerevisiae antibody) assay in inflammatory bowel disease. Gastroenterology 2001:120:827-33.
  • Oudkerk Pool M, Ellerbroek PM, Ridwan BU, Goldschmeding R, von Blomberg BM, Pena AS, et al. Serum antineutrophil cytoplasmic autoantibodies in inflammatory bowel disease are mainly associated with ulcerative colitis. A correlation study between perinuclear antineutrophil cytoplasmic autoantibodies and clinical parameters, medical, and surgical treatment. Gut 1993:34:46-50.
  • Peelers M, Joossens S, Vermeire S, Vlietinck R, Bossuyt X, Rutgeerts P. Diagnostic value of anti-Saccharomyce s cerevisiae and antineutrophil cytoplasmic autoantibodies in inflammatory bowel disease. Am J Gastroenterol 2001;96:730-4.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.