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Research Article

Collagenase-1 (MMP-1), matrilysin-1 (MMP-7), and stromelysin-2 (MMP-10) are expressed by migrating enterocytes during intestinal wound healing

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Pages 1095-1104 | Published online: 08 Jul 2009

References

  • Nagase H, Woessner JF, Jr. Matrix metalloproteinases. J Biol Chem 1999;274:21491–4.
  • Lohi J, Wilson CL, Roby JD, Parks WC. Epilysin, a novel human matrix metalloproteinase (MMP-28) expressed in testis and keratinocytes and in response to injury. J Biol Chem 2001;276: 10134–44.
  • Ravanti L, Kahari VM. Matrix metalloproteinases in wound repair [review]. Int J Mol Med 2000;6:391–407.
  • Parks WC. Matrix metalloproteinases in repair [review]. Wound Repair Regen 1999;7:423–2.
  • Pilcher BK, Dumin JA, Sudbeck BD, Krane SM, Welgus HG, Parks WC. The activity of collagenase-1 is required for keratinocyte migration on a type I collagen matrix. J Cell Biol 1997;137:1445–57.
  • Dunsmore SE, Saarialho-Kere UK, Roby JD, Wilson CL, Matrisian LM, Welgus HG, et al. Matrilysin expression and function in airway epithelium. J Clin Invest 1998;102:1321–31.
  • Legrand C, Polette M, Tournier JM, de Bentzmann S, Huet E, Monteau M, et al. uPA/plasmin system-mediated MMP-9 activation is implicated in bronchial epithelial cell migration. Exp Cell Res 2001;264: 326–36.
  • Sivak JM, Fini ME. MMPs in the eye: emerging roles for matrix metalloproteinases in ocular physiology [review]. Prog Retin Eye Res 2002;21:1–14.
  • Syk I, Agren MS, Adawi D, Jeppsson B. Inhibition of matrix metalloproteinases enhances breaking strength of colonic anastomoses in an experimental model. Br J Surg 2001; 88: 228–34.
  • Kiyama T, Onda M, Tokunaga A, Efron DT, Barbul A. Effect of matrix metalloproteinase inhibition on colonic anastomotic healing in rats. J Gastrointest Surg 2001;5:303–11.
  • Savage FJ, Lacombe DL, Boulos PB, Hembry RM. Role of matrix metalloproteinases in healing of colonic anastomosis. Dis Colon Rectum 1997;40:962–70.
  • Saarialho-Kere UK, Vaalamo M, Puolakkainen P, Airola K, Parks WC, Karjalainen-Lindsberg ML. Enhanced expression of matrilysin, collagenase, and stromelysin-1 in gastrointestinal ulcers. Am J Pathol 1996;148: 519–26.
  • Vaalamo M, Karjalainen-Lindsberg ML, Puolakkainen P, Kere J, Saarialho-Kere UK. Distinct expression profiles of stromelysin-2 (MMP-10), collagenase-3 (MMP-13), macrophage metallo-elastase (MMP-12), and tissue inhibitor of metalloproteinases-3 (TIMP-3) in intestinal ulcerations. Am J Pathol 1998;152:1005–14.
  • Pender SL, Tickle SP, Docherty AJ, Howie D, Wathen NC, MacDonald TT. A major role for matrix metalloproteinases in T cell injury in the gut. J Immunol 1997;158:1582–90.
  • Pender SL, Breese EJ, Gunther U, Howie D, Wathen NC, Schuppan D, et al. Suppression of T cell-mediated injury in human gut by interleukin 10: role of matrix metalloproteinases. Gastroenterology 1998;115:573–83.
  • Heuschkel RB, MacDonald TT, Monteleone G, Bajaj-Elliott M, Smith JA, Pender SL. Imbalance of stromelysin-1 and TIMP-1 in the mucosal lesions of children with inflammatory bowel disease. Gut 2000;47: 57–62.
  • MacDonald TT. The biochemical basis of immune enteropathy. J Pediatr Gastroenterol Nutr 2002;34 Suppl 1:S27–30.
  • Stallmach A, Chan CC, Ecker KW, Feifel G, Herbst H, Schuppan D, et al. Comparable expression of matrix metalloproteinases 1 and 2 in pouchitis and ulcerative colitis. Gut 2000;47:415–22.
  • Baugh MD, Perry MJ, Hollander AP, Davies DR, Cross SS, Lobo AJ, et al. Matrix metalloproteinase levels are elevated in inflammatory bowel disease. Gastroenterology 1999;117:814–22.
  • Saarialho-Kere UK, Chang ES, Welgus HG, Parks WC. Distinct localization of collagenase and tissue inhibitor of metalloproteinases expression in wound healing associated with ulcerative pyogenic granuloma. J Clin Invest 1992;90:1952–7.
  • Saarialho-Kere UK, Pentland AP, Birkedal-Hansen H, Parks WC, Welgus HG. Distinct populations of basal keratinocytes express stromelysin-1 and stromelysin-2 in chronic wounds. J Clin Invest 1994;94: 79–88.
  • McDonnell S, Navre M, Coffey RJ, Jr, Matrisian LM. Expression and localization of the matrix metalloproteinase pump-1 (MMP-7) in human gastric and colon carcinomas. Mol Carcinog 1991;4: 527–33.
  • Saarialho-Kere UK, Chang ES, Welgus HG, Parks WC. Expression of interstitial collagenase, 92-kDa gelatinase, and tissue inhibitor of metalloproteinases-1 in granuloma annulare and necrobiosis lipoidica diabeticorum. J Invest Dermatol 1993; 100:335–42.
  • Airola K, Ahonen M, Johansson N, Heikkila P, Kere J, Kahari VM, et al. Human TIMP-3 is expressed during fetal development, hair growth cycle, and cancer progression. J Histochem Cytochem 1998;46:437–47.
  • Rechardt O, Elomaa O, Vaalamo M, Paakkonen K, Jahkola T, Hook-Nikanne J, et al. Stromelysin-2 is upregulated during normal wound repair and is induced by cytokines. J Invest Dermatol 2000;115: 778–87.
  • Kerkela E, Ala-Aho R, Klemi P, Grenman S, Shapiro SD, Kahari VM, et al. Metalloelastase (MMP-12) expression by tumor cells in squamous cell carcinoma of the vulva correlates with invasiveness, while that by macrophages predicts better outcome. J Pathol 2002;198:258–69.
  • Heid CA, Stevens J, Livak KJ, Williams PM. Real time quantitative PCR. Genome Res 1996;6:986–94.
  • Seifert WF, Wobbes T, Hendriks T. Divergent patterns of matrix metalloproteinase activity during wound healing in ileum and colon of rats. Gut 1996;39:114–9.
  • Shaper KR, Savage FJ, Hembry RM, Boulos PB. Regulation of matrix metalloproteinases in a model of colonic wound healing in a rabbit. Dis Colon Rectum 2001;44:1857–66.
  • Arihiro S, Ohtani H, Hiwatashi N, Torii A, Sorsa T, Nagura H. Vascular smooth muscle cells and pericytes express MMP-1, MMP-9, TIMP-1 and type I procollagen in inflammatory bowel disease. Histopathology 2001;39:50–9.
  • Monteleone G, MacDonald TT. Manipulation of cytokines in the management of patients with inflammatory bowel disease. Ann Med 2000;32:552–60.
  • Monteleone G, Kumberova A, Croft NM, McKenzie C, Steer HW, MacDonald TT. Blocking Smad7 restores TGF-beta1 signaling in chronic inflammatory bowel disease. J Clin Invest 2001;108:601–9.
  • Jung S, Fehr S, Harder-d’Heureuse J, Wiedenmann B, Dignass AU. Corticosteroids impair intestinal epithelial wound repair mechanisms in vitro. Scand J Gastroenterol 2001;36:963–70.
  • Benbow U, Brinckerhoff CE. The AP-1 site and MMP gene regulation: what is all the fuss about? [review]. Matrix Biol 1997; 15:519–26.
  • Kermorgant S, Aparicio T, Dessirier V, Lewin MJ, Lehy T. Hepatocyte growth factor induces colonic cancer cell invasiveness via enhanced motility and protease overproduction. Evidence for PI3 kinase and PKC involvement. Carcinogenesis 2001;22: 1035–42.
  • Lopez-Boado YS, Wilson CL, Hooper LV, Gordon JI, Hultgren SJ, Parks WC. Bacterial exposure induces and activates matrilysin in mucosal epithelial cells. J Cell Biol 2000; 148: 1305–15.
  • Mirastschijski U, Impola U, Jahkola T, Karlsmark T, Agren MS, Saarialho-Kere U. Ectopic localization of matrix metalloproteinase-9 in chronic cutaneous wounds. Hum Pathol 2002; 33: 355–64.
  • Tarlton JF, Whiting CV, Tunmore D, Bregenholt S, Reimann J, Claesson MH, etal. The role of up-regulated serine proteases and matrix metalloproteinases in the pathogenesis of a murine model of colitis. Am J Pathol 2000;157:1927–35.
  • Salmela MT, MacDonald TT, Black D, Irvine B, Zhuma T, Saarialho-Kere U, et al. Upregulation of matrix metalloproteinases in a model of T cell mediated tissue injury in the gut: analysis by gene array and in situ hybridisation. Gut 2002;51: 540–7.
  • Vaalamo M, Weckroth M, Puolakkainen P, Kere J, Saarinen P, Lauharanta J, et al. Patterns of matrix metalloproteinase and TIMP-1 expression in chronic and normally healing human cutaneous wounds. Br J Dermatol 1996;135:52–9.
  • Vaalamo M, Leivo T, Saarialho-Kere U. Differential expression of tissue inhibitors of metalloproteinases (TIMP-1, -2, -3, and -4) in normal and aberrant wound healing. Hum Pathol 1999;30: 795–802.
  • Bister V-O, Salmela MT, Karjalainen-Lindsberg M-L, Uria J, Lohi J, Puolakkainen P, et al. Differential expression of three novel matrix metalloproteinases, MMP-19, matrilysin-2 (MMP-26), and epilysin (MMP-28), in normal and inflamed intestine and colon cancer. Dig Dis Sci 2004;49.
  • Di Sebastiano P, di Mola FF, Artese L, Rossi C, Mascetta G, Pernthaler H, et al. Beneficial effects of Batimastat (BB-94), a matrix metalloproteinase inhibitor, in rat experimental colitis. Digestion 2001;63:234–9.
  • Mirastschijski U, Impola U, Karsdal MA, Saarialho-Kere U, Agren MS. Matrix metalloproteinase inhibitor BB-3103 unlike the serine proteinase inhibitor aprotinin abrogates epidermal healing of human skin wounds ex vivo. J Invest Dermatol 2002; 118:55–64.
  • Bremer C, Tung CH, Weissleder R. In vivo molecular target assessment of matrix metalloproteinase inhibition. Nat Med 2001;7:743–8.
  • Vihinen P, Kahari VM. Matrix metalloproteinases in cancer: prognostic markers and therapeutic targets [review]. Int J Cancer 2002;99:157–66.

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