No major effect of the CD28/CTLA4/ICOS gene region on susceptibility to primary sclerosing cholangitis

References

• Chapman RW, Arborgh BA, Rhodes JM, Summerfield JA, Dick R, Scheuer PJ, et al. Primary sclerosing cholangitis: a review of its clinical features, cholangiography, and hepatic histology. Gut 1980; 21: 870–7
   PubMed Web of Science ®Google Scholar
• Bergquist A, Ekbom A, Olsson R, Kornfeldt D, Lööf L, Danielsson A, et al. Hepatic and extrahepatic malignancies in primary sclerosing cholangitis. J Hepatol 2002; 36: 321–7
   PubMed Web of Science ®Google Scholar
• Fausa O, Schrumpf E, Elgjo K. Relationship of inflammatory bowel disease and primary sclerosing cholangitis. Semin Liver Dis 1991; 11: 31–9
   PubMed Web of Science ®Google Scholar
• Saarinen S, Olerup O, Broomé U. Increased frequency of autoimmune diseases in patients with primary sclerosing cholangitis. Am J Gastroenterol 2000; 95: 3195–9
   PubMed Web of Science ®Google Scholar
• Cullen S, Chapman R. Primary sclerosing cholangitis. Autoimmun Rev 2003; 2: 305–12
   PubMed Web of Science ®Google Scholar
• Donaldson PT, Norris S. Immunogenetics in PSC. Best Pract Res Clin Gastroenterol 2001; 15: 611–27
   PubMed Web of Science ®Google Scholar
• Donaldson PT. Genetics of autoimmune and viral liver diseases; understanding the issues. J Hepatol 2004; 41: 327–32
   PubMedGoogle Scholar
• Ling V, Wu PW, Finnerty HF, Agostino MJ, Graham JR, Chen S, et al. Assembly and annotation of human chromosome 2q33 sequence containing the CD28, CTLA4, and ICOS gene cluster: analysis by computational, comparative, and microarray approaches. Genomics 2001; 78: 155–68
   PubMed Web of Science ®Google Scholar
• Rudd CE, Schneider H. Unifying concepts in CD28, ICOS and CTLA4 co-receptor signalling. Nat Rev Immunol 2003; 3: 544–56
   PubMed Web of Science ®Google Scholar
• Kristiansen OP, Larsen ZM, Pociot F. CTLA-4 in autoimmune diseases: a general susceptibility gene to autoimmunity?. Genes Immun 2000; 1: 170–84
   PubMed Web of Science ®Google Scholar
• Agarwal K, Jones DE, Daly AK, James OF, Vaidya B, Pearce S, et al. CTLA-4 gene polymorphism confers susceptibility to primary biliary cirrhosis. J Hepatol 2000; 32: 538–41
   PubMed Web of Science ®Google Scholar
• Agarwal K, Czaja AJ, Jones DE, Donaldson PT. Cytotoxic T lymphocyte antigen-4 (CTLA-4) gene polymorphisms and susceptibility to type 1 autoimmune hepatitis. Hepatology 2000; 31: 49–53
   PubMed Web of Science ®Google Scholar
• Saarinen S, Broome U, Liger A, Olsson R, Hultcrantz R, Olerup O. CTLA-4 gene polymorphism associated with primary sclerosing cholangitis (PSC). J Hepatology 1998; 28 Suppl 1: 24
   Google Scholar
• Agarwal K, Hudson M, Harrison P, Straussbourg C, Manns MP, Donaldson P. No association between primary sclerosing cholangitis (PSC) and CTLA-4 gene polymorphism: evidence against an autoimmune aetiology?. Hepatology 2000; 32 Suppl 1: 173A
   Google Scholar
• Ueda H, Howson JM, Esposito L, Heward J, Snook H, Chamberlain G, et al. Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. Nature 2003; 423: 506–11
   PubMed Web of Science ®Google Scholar
• Schneider S, Roessli D, Excoffei L. Arlequin. Genetics and Biometry Laboratory, University of Geneva, Switzerland. 2000
   Google Scholar
• Klitz W, Stephens JC, Grote M, Carrington M. Discordant patterns of linkage disequilibrium of the peptide-transporter loci within the HLA class II region. Am J Hum Genet 1995; 57: 1436–44
   PubMedGoogle Scholar
• Blomhoff A, Lie BA, Myhre AG, Kemp EH, Weetman AP, Akselsen HE, et al. Polymorphisms in the cytotoxic T lymphocyte antigen-4 gene region confer susceptibility to Addison's disease. J Clin Endocrinol Metab 2004; 89: 3474–6
   PubMed Web of Science ®Google Scholar
• Wiencke K, Spurkland A, Schrumpf E, Boberg KM. Primary sclerosing cholangitis is associated to an extended B8-DR3 haplotype including particular MICA and MICB alleles. Hepatology 2001; 34: 625–30
   PubMed Web of Science ®Google Scholar
• Ban Y, Davies TF, Greenberg DA, Kissin A, Marder B, Murphy B, et al. Analysis of the CTLA-4, CD28, and inducible co-stimulator (ICOS) genes in autoimmune thyroid disease. Genes Immun 2003; 4: 586–93
   PubMed Web of Science ®Google Scholar
• Colhoun HM, McKeigue PM, Davey SG. Problems of reporting genetic associations with complex outcomes. Lancet 2003; 361: 865–72
   PubMed Web of Science ®Google Scholar
• Wood JP, Pani MA, Bieda K, Meyer G, Usadel KH, Badenhoop K. A recently described polymorphism in the CD28 gene on chromosome 2q33 is not associated with susceptibility to type 1 diabetes. Eur J Immunogenet 2002; 29: 347–9
   PubMedGoogle Scholar
• Hampe J, Grebe J, Nikolaus S, Solberg C, Croucher PJ, Mascheretti S, et al. Association of NOD2 (CARD 15) genotype with clinical course of Crohn's disease: a cohort study. Lancet 2002; 359: 1661–5
   PubMed Web of Science ®Google Scholar
• Donaldson PT, Norris S. Evaluation of the role of MHC class II alleles, haplotypes and selected amino acid sequences in primary sclerosing cholangitis. Autoimmunity 2002; 35: 555–64
   PubMed Web of Science ®Google Scholar
• Wiencke K, Louka AS, Spurkland A, Vatn M, Schrumpf E, Boberg KM. Association of matrix metalloproteinase-1 and -3 promoter polymorphisms with clinical subsets of Norwegian primary sclerosing cholangitis patients. J Hepatol 2004; 41: 209–14
   PubMed Web of Science ®Google Scholar