Endoscopic biopsies in Ussing chambers evaluated for studies of macromolecular permeability in the human colon

References

• Bjarnason I, MacPherson A, Hollander D. Intestinal permeability: an overview. Gastroenterology 1995;108:1566–81.
   Google Scholar
• Holtug K, Hansen MB, Skadhauge E. Experimental studies of intestinal ion and water transport. Scand J Gastroenterol 1996;Suppl 216:95–110.
   Google Scholar
• Lennernäs H. Human intestinal permeability. J Pharm Sci 1998;87:403–10.
   PubMed Web of Science ®Google Scholar
• Albin DM, Tappenden KA. Advances in methods to evaluate gastrointestinal transport function. Curr Opin Clin Nutr Metab Care 2001;4:351–4.
   PubMedGoogle Scholar
• Soderholm JD, Perdue MH, II. Stress and intestinal barrier function. Am J Physiol Gastrointest Liver Physiol 2001; 280:G7–G13.
   PubMedGoogle Scholar
• Harvey BJ, Alzamora R, Healy V, Renard C, Doolan CM. Rapid responses to steroid hormones: from frog skin to human colon. A homage to Hans Ussing. Biochim Biophys Acta 2002;1566:116–28.
   Google Scholar
• Nejdfors P, Wang Q, Ekelund M, Weström BR, Jansson O, Lindström CL, et al. Increased colonic permeability in patients with ulcerative colitis: an in vitro study. Scand J Gastroenterol 1998;33: 749–73.
   PubMedGoogle Scholar
• Nejdfors P, Ekelund M, Jeppsson B, Weström BR. Mucosal in vitro permeability in the intestinal tract of the pig, the rat, and man: species- and region-related differences. Scand J Gastroenterol 2000;35: 501–7.
   Google Scholar
• Riegler M, Sedivy R, Sogukoglu T, Castagliuolo I, Pothoulakis C, Cosentini E, et al. Epidermal growth factor attenuates Clostridium difficile toxin A- and B-induced damage of human colonic mucosa. Am J Physiol 1997; 273:G1014–G22.
   Google Scholar
• Soderholm JD, Peterson KH, Olaison G, Franzen LE, Weström B, Magnusson KE, et al. Epithelial permeability to proteins in the noninflamed ileum of Crohn’s disease? Gastroenterology 1999;117:65–72.
   Google Scholar
• Söderholm JD, Hedman L, Artursson P, Franzen L, Larsson J, Pantzar N, et al. Integrity and metabolism of human ileal mucosa in vitro in the Ussing chamber. Acta Physiol Scand 1998;162: 47–56.
   PubMedGoogle Scholar
• Soderholm JD, Olaison G, Peterson KH, Franzen LE, Lindmark T, Wiren M, et al. Augmented increase in tight junction permeability by luminal stimuli in the non-inflamed ileum of Crohn’s disease. Gut 2002;50:307–13.
   PubMed Web of Science ®Google Scholar
• Fink MP. Intestinal epithelial hyperpermeability: update on the pathogenesis of gut mucosal barrier dysfunction in critical illness. Curr Opin Crit Care 2003;9:143–51.
   PubMedGoogle Scholar
• Bijlsma PB, Peeters RA, Groot JA, Dekker PR, Taminiau JA, Van Der MR. Differential in vivo and in vitro intestinal permeability to lactulose and mannitol in animals and humans: a hypothesis. Gastroenterology 1995;108: 687–96.
   Google Scholar
• Stockmann M, Fromm M, Schmitz H, Schmidt W, Riecken EO, Schulzke JD. Duodenal biopsies of HIV-infected patients with diarrhoea exhibit epithelial barrier defects but no active secretion. AIDS 1998;12:43–51.
   PubMed Web of Science ®Google Scholar
• Stockmann M, Gitter AH, Sorgenfrei D, Fromm M, Schulzke JD. Low edge damage container insert that adjusts intestinal forceps biopsies into Ussing chamber systems. Pflugers Arch 1999;438: 10^^12.
   Google Scholar
• Larsen R, Mertz-Nielsen A, Hansen MB, Poulsen SS, Bindslev N. Novel modified Ussing chamber for the study of absorption and secretion in human endoscopic biopsies. Acta Physiol Scand 2001;173:213–2.
   PubMedGoogle Scholar
• Kroesen AJ, Stockmann M, Ransco C, Schulzke JD, Fromm M, Buhr HJ. Impairment of epithelial transport but not of barrier function in idiopathic pouchitis after ulcerative colitis. Gut 2002;50:821–6.
   PubMedGoogle Scholar
• Reims A, Redfors S, Ascher H, Strandvik B. Electrogenic ion transport in duodenal biopsies from children with coeliac disease. Scand J Gastroenterol 2002;37:43–50.
   PubMed Web of Science ®Google Scholar
• Malin M, Isolauri E, Pikkarainen P, Karikoski R, Isolauri J. Enhanced absorption of macromolecules. A secondary factor in Crohn’s disease. Dig Dis Sci 1996;41:1423–8.
   Google Scholar
• Matysiak-Budnik T, Coffin B, Lavergne-Slove A, Sabate JM, Megraud F, Heyman M. Helicobacter pylori increases the epithelial permeability to a food antigen in human gastric biopsies. Am J Gastroenterol 2004;99:225–32.
   Google Scholar
• Grass GM, Sweetana SA. In vitro measurement of gastrointestinal tissue permeability using a new diffusion cell. Pharm Res 1988;5:372–6.
   PubMed Web of Science ®Google Scholar
• Karlsson J. Drug absorption in cell culture models of the intestinal epithelium [dissertation]. Sweden: Pharmaceuticals, Uppsala University; 1995.
   Google Scholar
• Madara JL, Trier JS. Structure and permeability of goblet cell tight junctions in rat small intestine. J Membr Biol 1982;66:145–57.
   PubMedGoogle Scholar
• Velin ÅK, Ericson AC, Braaf Y, Wallon C, Söderholm JD. Increased antigen and bacterial uptake in follicle associated epithelium induced by chronic psychological stress in rats. Gut 2004;53:494–500.
   Google Scholar
• Anderberg EK, Lindmark T, Artursson P. Sodium caprate elicits dilatations in human intestinal tight junctions and enhances drug absorption by the paracellular route. Pharm Res 1993;10:857–64.
   Google Scholar
• Nilsson M, Molne J, Ericson LE. Integrity of the occluding barrier in high-resistant thyroid follicular epithelium in culture. II. Immediate protective effect of TSH on paracellular leakage induced by Ca2+ removal and cytochalasin B, Eur J Cell Biol 1991;56: 308–18.
   Google Scholar
• Söderholm JD, Oman H, Blomquist L, Veen J, Lindmark T, Olaison G. Reversible increase in tight junction permeability to macromolecules in rat ileal mucosa in vitro by sodium caprate, a constituent of milk fat. Dig Dis Sci 1998;43: 1547–52.
   Google Scholar
• Padley FB, Gunstone FD, Harwood JL. Occurrence and characteristics of oils and fats. Animal fats: milk and depot fats. In: Gunstone FD, Harwood JL, Padley FB, editors. The lipid handbook. London: Chapman & Hall; 1994. pp 147–66.
   Google Scholar
• Graham RC, Jr, Karnovsky MJ. Glomerular permeability. Ultrastructural cytochemical studies using peroxidases as protein tracers. J Exp Med 1966;124:1123–34.
   Google Scholar
• Söderholm JD, Yang PC, Ceponis P, Vohra A, Riddell R, Sherman PM, et al. Chronic stress induces mast cell-dependent bacterial adherence and initiates mucosal inflammation in rat intestine. Gastroenterology 2002;123:1099–108.
   PubMed Web of Science ®Google Scholar
• Harris RC, Hultman E, Nordesjö LO. Glycogen, glycolytic intermediates and high-energy phosphates determined in biopsy samples of musculus quadriceps femoris of man at rest. Methods and variance of values. Scand J Clin Lab Invest 1974;33:109–20.
   Google Scholar
• Sakai M, Imai T, Ohtake H, Azuma H, Otagiri M. Effects of absorption enhancers on cytoskeletal actin filaments in Caco-2 cell monolayers. Life Sci 1998;63: 45–54.
   Google Scholar
• Hemlin M, Jodal M, Lundgren O, Sjövall H, Stage L. The importance of the subepithelial resistance for the electrical properties of the rat jejunum in vitro. Acta Physiol Scand 1988;134:79–88.
   Google Scholar
• Schmitz H, Barmeyer C, Fromm M, Runkel N, Foss HD, Bentzel CJ, et al. Altered tight junction structure contributes to the impaired epithelial barrier function in ulcerative colitis. Gastroenterology 1999;116:301–9.
   PubMed Web of Science ®Google Scholar
• Yu LC, Perdue MH. Role of mast cells in intestinal mucosal function: studies in models of hypersensitivity and stress. Immunol Rev 2001;179:61–73.
   PubMedGoogle Scholar
• Söderholm JD, Streutker C, Yang PC, Paterson C, Singh PK, McKay DM, et al. Increase epithelial uptake of protein antigens in the ileum of Crohn’s disease mediated by TNFα Gut 2004;53: 1817–24.
   Google Scholar