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CASE REPORT

Esophageal giant ulcer in primary human immunodeficiency virus infection is associated with an infiltration of activated T cells

, , PhD, , , , & show all
Pages 890-895 | Received 26 Jun 2006, Published online: 08 Jul 2009

References

  • Hirschel B. Primary HIV infection. Infectious diseases, D Armstrong, J Cohen. Mosby, London, Philadelphia, St. Louis, Tokyo 1999; 2: 8.1–8.4
  • Rabeneck L, Popovic M, Gartner S, McLean DM, McLeod WA, Read E, et al. Acute HIV infection presenting with painful swallowing and esophageal ulcers. JAMA 1990; 263: 2318–22
  • Smith PD, Fox CH, Masur H, Winter HS, Alling DW. Quantitative analysis of mononuclear cells expressing human immunodeficiency virus type 1 RNA in esophageal mucosa. J Exp Med 1994; 180: 1541–6
  • Li Q, Duan L, Estes JD, Ma ZM, Rourke T, Wang Y, et al. Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells. Nature 2005; 434: 1148–52
  • Mattapallil JJ, Douek DC, Hill B, Nishimura Y, Martin M, Roederer M. Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection. Nature 2005; 434: 1093–7
  • Loddenkemper C, Anagnostopoulos I, Hummel M, Johrens-Leder K, Foss HD, Jundt F, et al. Differential EMU enhancer activity and expression of BOB.1/OBF.1, Oct2, PU.1, and immunoglobulin in reactive B-cell populations, B-cell non-Hodgkin lymphomas, and Hodgkin lymphomas. J Pathol 2004; 202: 60–9
  • Cordell JL, Falini B, Erber WN, Ghosh AK, Abdulaziz Z, MacDonald S, et al. Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes). J Histochem Cytochem 1984; 32: 219–29
  • Savarino A, Bottarel F, Malavasi F, Dianzani U, Heise C, Miller CJ, et al. Role of CD38 in HIV-1 infection: an epiphenomenon of T-cell activation or an active player in virus/host interactions?. Aids 2000; 14: 1079–89
  • Wilcox CM, Schwartz DA. Comparison of two corticosteroid regimens for the treatment of HIV-associated idiopathic esophageal ulcer. Am J Gastroenterol 1994; 89: 2163–7
  • Fidler S, Oxenius A, Brady M, Clarke J, Cropley I, Babiker A, et al. Virological and immunological effects of short-course antiretroviral therapy in primary HIV infection. AIDS 2002; 16: 2049–54
  • Borum ML, Marks YH. Esophageal strictures from idiopathic ulcers in an AIDS patient: a case report and a review of the literature. J Clin Gastroenterol 1999; 28: 260–1
  • Houghton JM, Korah RM, Kim KH, Small MB. A role for apoptosis in the pathogenesis of AIDS-related idiopathic esophageal ulcers. J Infect Dis 1997; 175: 1216–9
  • Heise C, Miller CJ, Lackner A, Dandekar S. Primary acute simian immunodeficiency virus infection of intestinal lymphoid tissue is associated with gastrointestinal dysfunction. J Infect Dis 1994; 169: 1116–20
  • Donze HH, Cummins JE, Jr, Schwiebert RS, Kantele A, Han Y, Fultz PN, et al. HIV-1/simian immunodeficiency virus infection of human and nonhuman primate lymphocytes results in the migration of CD2+ T cells into the intestine of engrafted SCID mice. J Immunol 1998; 160: 2506–13
  • Sopper S, Nierwetberg D, Halbach A, Sauer U, Scheller C, Stahl-Hennig C, et al. Impact of simian immunodeficiency virus (SIV) infection on lymphocyte numbers and T-cell turnover in different organs of rhesus monkeys. Blood 2003; 101: 1213–9
  • Schneider T, Jahn HU, Schmidt W, Riecken EO, Zeitz M, Ullrich R. Loss of CD4 T lymphocytes in patients infected with human immunodeficiency virus type 1 is more pronounced in the duodenal mucosa than in the peripheral blood. Berlin Diarrhea/Wasting Syndrome Study Group. Gut 1995; 37: 524–9
  • Kewenig S, Schneider T, Hohloch K, Lampe-Dreyer K, Ullrich R, Stolte N, et al. Rapid mucosal CD4(+) T-cell depletion and enteropathy in simian immunodeficiency virus-infected rhesus macaques. Gastroenterology 1999; 116: 1115–23
  • Veazey RS, DeMaria M, Chalifoux LV, Shvetz DE, Pauley DR, Knight HL, et al. Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection. Science 1998; 280: 427–31
  • Smit-McBride Z, Mattapallil JJ, McChesney M, Ferrick D, Dandekar S. Gastrointestinal T lymphocytes retain high potential for cytokine responses but have severe CD4(+) T-cell depletion at all stages of simian immunodeficiency virus infection compared to peripheral lymphocytes. J Virol 1998; 72: 6646–56
  • Rosenberg YJ, Cafaro A, Brennan T, Greenhouse JG, Villinger F, Ansari AA, et al. Virus-induced cytokines regulate circulating lymphocyte levels during primary infections. Int Immunol 1997; 9: 703–12
  • Famularo G, Moretti S, Marcellini S, Nucera E, De Simone C. CD8 lymphocytes in HIV infection: helpful and harmful. J Clin Lab Immunol 1997; 49: 15–32
  • Jacobson JM, Spritzler J, Fox L, Fahey JL, Jackson JB, Chernoff M, et al. Thalidomide for the treatment of esophageal aphthous ulcers in patients with human immunodeficiency virus infection. National Institute of Allergy and Infectious Disease AIDS Clinical Trials Group. J Infect Dis 1999; 180: 61–67
  • Smith PD, Meng G, Sellers MT, Rogers TS, Shaw GM. Biological parameters of HIV-1 infection in primary intestinal lymphocytes and macrophages. J Leukoc Biol 2000; 68: 360–5

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