206
Views
38
CrossRef citations to date
0
Altmetric
ORIGINAL ARTICLE

Lactose malabsorption in the elderly: Role of small intestinal bacterial overgrowth

, , , , &
Pages 146-154 | Received 24 Jul 2007, Published online: 08 Jul 2009

References

  • Di Stefano M, Veneto G, Malservisi S, Strocchi A, Corazza GR. Lactose malabsorption in the elderly. Scand J Gastroenterol 2001; 36: 1274–8
  • Feibusch JH, Holt PR. Impaired absorptive capacity for carbohydrate in the ageing human. Dig Dis Sci 1982; 27: 1095–100
  • Goulding A, Taylor RW, Keil D, Gold E, Lewis-Barned NJ, Williams SM. Lactose malabsorption and rate of bone loss in older women. Age Ageing 1999; 28: 175–80
  • Rao DM, Bello H, Warren AP, Brown GE. Prevalence of lactose maldigestion. Influence and interaction of age, race and sex. Dig Dis Sci 1994; 39: 1519–24
  • Rorick MH, Scrimshaw NS. Comparative tolerance of elderly from differing ethnic backgrounds to lactose-containing and lactose-free dairy drinks: a double-blind study. J Gerontology 1979; 34: 191–6
  • Wallis JL, Lipski PS, Mathers JC, James OFW, Hirst BH. Duodenal brush-border mucosal glucose transport and enzyme activities in aging man and effect of bacterial contamination of the small intestine. Dig Dis Sci 1993; 38: 403–9
  • Corazza GR, Ginaldi L, Quaglione G, Ponzielli F, Vecchio L, Quaglino D, et al. Proliferating cell nuclear antigen expression is increased in small bowel epithelium in the elderly. Mech Ageing Dev 1998; 104: 1–9
  • Ciccocioppo R, Di Sabatino A, Luinetti O, Rossi M, Cifone MG, Corazza GR. Small bowel enterocyte apoptosis and proliferation are increased in the elderly. Gerontology 2002; 48: 204–8
  • Holt PR, Tierney AR, Kotler DP. Delayed enzyme expression: a defect of aging rat gut. Gastroenterology 1985; 89: 1026–34
  • Holt PR, Heller TD, Richardson AG. Food restriction retards age-related biochemical changes in rat small intestine. J Gerontol 1991; 46: B89–94
  • Lee MF, Russell RM, Montgomery RK, Krasinski SD. Total intestinal lactase and sucrase activities are reduced in aged rats. J Nutr 1997; 127: 1382–7
  • Darmenton P, Raul F, Doffoel M, Wessley J-Y. Age influence on sucrose hydrolysis and on monosaccharide absorption along the small intestine of rat. Mech Ageing Dev 1989; 50: 49–55
  • Triadou N, Bataille J, Schmitz J. Longitudinal study of the human intestinal brush border membrane proteins. Distribution of the main disaccharidases and peptidases. Gastroenterology 1983; 85: 1326–32
  • Elphick HL, Elphick DA, Sanders DS. Small bowel bacterial overgrowth. An under-recognized cause of malnutrition in older adults. Geriatrics 2006; 61: 21–6
  • Holt PR. Diarrhoea and malabsorption in the elderly. Gastroenterol Clin N Am 2001; 30: 427–44
  • Riordan SM, McIver CJ, Wakefield D, Bolin TD, Duncombe VM, Thomas MC. Small intestinal bacterial overgrowth in the symptomatic elderly. Am J Gastroenterol 1997; 92: 47–51
  • Haboubi NY, Cowley PA, Lee GS. Small bowel bacterial overgrowth: a cause of malnutrition in the elderly?. Eur J Clin Nutr 1988; 42: 999–1005
  • Riordan SM, McIver CJ, Walker BM, Duncombe VM, Bolin TD, Thomas MC. The lactulose breath hydrogen test and small intestinal bacterial overgrowth. Am J Gastroenterol 1996; 91: 1795–1803
  • Quigley EM, Quera R. Small intestinal bacterial overgrowth: roles of antibiotics, prebiotics, and probiotics. Gastroenterology 2006; 130(Suppl 1)S78–90
  • Beaumont DM, Cobden I, Sheldon WL, Laker MF, James OFW. Passive and active carbohydrate absorption by the ageing gut. Age Ageing 1987; 16: 294–300
  • Elia M, Behrens R, Northrop C, Wraight P, Neale G. Evaluation of mannitol, lactulose and 51Cr-labelled ethylenediaminetetra-acetate as markers of intestinal permeability in man. Clin Sci 1987; 73: 197–204
  • Perman JA, Barr RG, Watkins JB. Sucrose malabsorption in children: non-invasive diagnosis by interval breath hydrogen determination. J Pediatr 1978; 93: 17–22
  • Anderson IH, Levine AS, Levitt MD. Incomplete absorption of the carbohydrate in all purpose wheat flour. N Engl J Med 1981; 304: 891–2
  • Thompson DG, O'Brien JD, Hardie JM. Influence of the oropharyngeal microflora on the measurement of exhaled breath hydrogen. Gastroenterology 1986; 91: 853–60
  • Thompson DG, Binfield P, De Delder A, O'Brien J, Warren S, Wilson M. Extra intestinal influences on exhaled breath hydrogen measurements during the investigation of gastrointestinal disease. Gut 1985; 26: 1349–52
  • Riordan SM, McIver CJ, Thomas DH, Duncombe VM, Bolin TD, Thomas MC. Luminal bacteria and small intestinal permeability. Scand J Gastroenterol 1997; 32: 556–63
  • Gorbach SL, Nahas L, Lerner PI, Weinstein L. Studies of intestinal microflora. Gastroenterology 1967; 53: 845–55
  • Simon GL, Gorbach SL. The human intestinal microflora. Dig Dis Sci 1986; 31(Suppl 1)147–62
  • Valdovinos MA, Camilleri M, Thomforde GM, Frie C. Reduced accuracy of 14C-D-xylose breath test for detecting bacterial overgrowth in gastrointestinal motility disorders. Scand J Gastroenterol 1993; 28: 963–8
  • Dahlquist A. Assay of intestinal disaccharidases. Scand J Clin Lab Invest 1984; 44: 169–72
  • Lowry OH, Rosenbrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem 1951; 193: 265–75
  • Pimentel M, Chow EJ, Lin HC. Normalization of lactulose breath testing correlates with symptom improvement in irritable bowel syndrome: A double-blind, randomized, placebo-controlled study. Am J Gastroenterol 2003; 98: 412–9
  • Suarez FL, Adshead J, Furne JK, Levitt MD. Lactose maldigestion is not an impediment to the intake of 1500 mg calcium daily as dairy products. Am J Clin Nutr 1998; 68: 1118–22

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.