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Research Article

Tuberculosis DNA Vaccines

Pages 74-76 | Published online: 08 Jul 2009

  • Ulmer JB, Liu MA. Gene-based vaccines. Mol Ther 2000; 1: 396–9.
  • Tang DC, Devit M, Johnston SA. Genetic immunization is a simple method for eliciting an immune response. Nature 1992; 356: 152–4.
  • Ulmer JB, Donnelly JJ, Parker SE, Rhodes GH, Feigner PL, Dwarki VJ, et al. Heterologous protection against influenza by injection of DNA encoding a viral protein. Science 1993; 259: 1745–9.
  • Donnelly J, Ulmer J, Shiver J, Liu M. DNA vaccines. Ann Rev Immunol 1997; 15: 617–8.
  • Wang R, Doolan DL, Le TP, Hedstrom RC, Coonan KM, Charoenvit Y, et al. Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine. Science 1998; 282: 476–80.
  • Tascon RE, Colston MJ, Ragno S, Stavropoulos E, Gregory D, Lowrie DB. Vaccination against tuberculosis by DNA injection. Nature Med 1996; 2: 888–92.
  • Huygen K, Content J, Denis O, Montgomery DL, Yawman AM, Deck RR, et al. Immunogenicity and protective efficacy of a tuberculosis DNA vaccine. Nature Med 1996; 2: 893–8.
  • Baldwin SL, D’Souza C, Roberts AD, Kelly BP, Frank AA, Huygen K, et al. Evaluation of new vaccines in mouse and guinea pig models of tuberculosis. Infect Immun 1998; 66: 2951–9.
  • Zhu X, Venkataprasad N, Thangaraj HS, Hill M, Singh M, Ivanyi J, et al. Functions and specificity of T cells following nucleic acid vaccination of mice against Mycobacterium tuberculosis infection. J Immunol 1997; 158 : 5921–6.
  • Tanghe A, Lefevre P, Denis O, D’Souza S, Braibant M, Lozes E, et al. Immunogenicity and protective efficacy of tuberculosis DNA vaccines encoding putative phosphate transport receptors. J Immunol 1999; 162: 1113–9.
  • Morris S, Kelley C, Howard A, Li Z, Collins F. The immunogenicity of single and combination DNA vaccines against tuberculosis. Vaccine 2000; 18: 2155–63.
  • Dillon DC, Alderson MR, Day CH, Lewinsohn DM, Coler R, Bement T, et al. Molecular characterization and human T-cell responses to a member of a novel Mycobacterium tuberculosis mtb39 gene family. Infect Immun 1999; 67: 2941–50.
  • Lowrie DB, Tascon RE, Bonato VLD, Lima VMF, Faccioli LH, Stavropoulos E, et al. Therapy of tuberculosis in mice by DNA vaccination. Nature 1999; 400: 269–71.
  • Velaz-Faircloth M, Cobb AJ, Horstman AL, Henry SC, Frothingham R. Protection against Mycobacterium avium by DNA vaccines expressing mycobacterial antigens as fusion proteins with green fluorescent protein. Infect Immun 1999; 67: 4243–50.
  • Martin E, Kamath AT, Triccas JA, Britton WJ. Protection against virulent Mycobacterium avium infection following DNA vaccination with the 35 Kilodalton antigen is accompanied by induction of gamma interferon-secreting CD4 + T cells. Infect Immun 2000; 68: 3090–96.
  • Baldwin SL, D’Souza C, Orme IM, Liu MA, Huygen K, Denis O, et al. Immunogenicity and protective efficacy of DNA vaccines encoding secreted and non-secreted forms of M. tuberculosis Ag85A. Tuber Lung Dis 1999; 79: 251–9.
  • Tanghe A, Denis O, Lambrecht B, Motte V, van den Berg T, Huygen K. Tuberculosis DNA vaccine encoding Ag85A is immunogenic and protective when administered by intramuscular needle injection but not by epidermal gene gun bombardment. Infect Immun 2000; 68: 3854–60.
  • Walsh GP, Tan EV, de la Cruz EC, Abalos RM, Villahermosa LG, Young LJ, et al. The Phillipine cynomolgus monkey provides a new nonhuman primate model of tuberculosis that resembles human disease. Nature Med 1996; 2: 430–6.
  • Kamath AT, Feng CG, MacDonald M, Briscoe H, Britton WJ. Differential protective efficacy of DNA vaccines expressing secreted proteins of Mycobacterium tuberculosis. Infect Immun 1999; 67: 1702–7.
  • Li Z, Howard A, Kelley C, Delogu G, Collins F, Morris S. Immunogenicity of DNA vaccines expressing tuberculosis proteins fused to tissue plasminogen activator signal sequences. Infect Immun 1999; 67: 4780–6.
  • Delogu G, Howard A, Collins FM, Morris SL. DNA vaccination against tuberculosis: expression of a ubiquitin-conjugated tuberculosis protein enhances antimycobacterial immunity. Infect Immun 2000; 68: 3097–102.
  • Ulmer JB, DeWitt CM, Chastain M, Friedman A, Donnelly JJ, McClements W, et al. Enhancement of DNA vaccine potency using conventional aluminum adjuvants. Vaccine 1999; 18: 18–28.
  • Dupuis M, Denis-Mize K, Woo C, Goldbeck C, Selby MJ, Ulmer JB, et al. Distribution of DNA vaccines determines their immunogenicity after intramuscular injection in mice. J Immunol 2000; 165: 2850–8.
  • Widera G, Austin M, Rabussay D, Goldbeck C, Barnett S, Chen M, et al. Increased DNA vaccine delivery and immunogenicity by electroporation in vivo. J Immunol 2000; 164: 4635–40.
  • Singh M, Briones M, Ott G, O’Hagan D. Cationic microparticles: a potent delivery system for DNA vaccines. Proc Natl Acad Sci USA 2000; 97: 811–16.
  • Denis O, Tanghe A, Palfliet K, Jurion F, van den Berg T-P, Vanonckelen A, et al. Vaccination with plasmid DNA encoding Ag85A stimulates a broader CD4 + and CD8 + T cell epitopic repertoire than infection with M. tuberculosis H37Rv. Infect Immun 1998; 66: 1527–33.

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