Advanced search
Publication Cover
Scandinavian Journal of Infectious Diseases Volume 36, 2004 - Issue 3
Submit an article Journal homepage
55
Views
10
CrossRef citations to date
0
Altmetric
Original Paper

Diagnostic Value of Bronchoalveolar Lavage in Community-acquired Pneumonia in a Routine Setting: A Study on Patients Treated in a Finnish University Hospital

Ulla Hohenthal Medicine, TurkuCorrespondence[email protected]
,
Jukka Sipilä Otorhinolaryngology, Turku
,
Raija Vainionpää Clinical Microbiology, Turku University Central Hospital, Kiinamyllynkatu 4-8, 20520, Turku
,
Olli Meurman Virology, Turku University, 20520 Turku
,
Kaisu Rantakokko-jalava Medical Microbiology, Turku University, Kiinamyllynkatu 13, 20520 Turku
,
Jukka Nikoskelainen Antimicrobial Research Laboratory, National Public Health Institute, Kiinamyllynkatu 13, 20520 Turku
&
Pirkko Kotilainen Medicine, Turku
 show all
Pages 198-203 | Received 04 Sep 2003, Accepted 15 Dec 2003, Published online: 08 Jul 2009

  • Rośon B, Carratalà J, Dorca J, Casanova A, Manresa F, Gudiol F. Aetiology, reasons for hospitalization, risk classes, and outcomes of community-acquired pneumonia in patients hospitalized on the basis of conventional admission criteria. Clin Infect Dis 2001; 33: 158–65.
  • Ewig S, Bauer T, Hasper E, Marklein G, Kubini R, Lüderitz B. Value of routine microbial investigation in community-acquired pneumonia treated in a tertiary care centre. Respiration 1996; 63: 164–9.
  • Ruiz M, Ewig S, Marcos MA, Martinez JA, Arancibia F, Mensa J, Torres A. Aetiology of community-acquired pneumonia: impact of age, comorbidity, and severity. Am J Respir Crit Care Med 1999; 160: 397–405.
  • Sočan M, Marinič-Fišer N, Kraigher A, Kotnik A, Logar M. Microbial aetiology of community-acquired pneumonia inhospitalized patients. Eur J Clin Microbiol Infect Dis 1999; 18: 111–82.
  • Korsgaard J, Rasmussen TR, Sommer T, Møller Jk, Jensen JS, Kilian M. Intensified microbiological investigations in adult patients admitted to hospital with lower respiratory tract infections. Resp Med 2002; 96: 344–51.
  • Ewig S, Schlochtermeier M, Göke N, Niederman MS. Applying sputum as a diagnostic tool in pneumonia: limited yield, minimal impact on treatment decisions. Chest 2002; 121: 1486–92.
  • Sopena N, Sabrià M, Pedro-Botet ML, Manterola JM, Matas L, Dominguez J, et al. Prospective study of community-acquired pneumonia of bacterial aetiology in adults. Eur J Clin Microbiol Infect Dis 1999; 18: 852–8.
  • Gotfried MH. Epidemiology of clinically diagnosed community-acquired pneumonia in the primary care setting: results from the 1999–2000 respiratory surveillance programme. Am J Med 2001; 111(9A): 25S–9S.
  • Lagerström F, Bader M, Foldevi M, Fredlund H, Nordin-Olsson I, Holmberg H. Microbiological aetiology in clinically diagnosed community-acquired pneumonia in primary care in Örebro, Sweden. Clin Microbiol Infect 2003; 9: 645–52.
  • Stover DE, Zaman MB, Hajdu SI, Lange M, Gold J, Armstrong D. Bronchoalveolar lavage in the diagnosis of diffuse pulmonary infiltrates in the immunosuppressed host. Ann Intern Med 1984; 101: 1–1.
  • Hohenadel IA, Kiworr M, Genitsariotis R, Zeidler D, Lorenz J. Role of bronchoalveolar lavage in immunocompromized patients with pneumonia treated with a broad spectrum antibiotic and antifungal regimen. Thorax 2001; 56: 115–20.
  • Rañó A, Augustí C, Jimenez P, Angrill J, Benito N, Danéés C, et al. Pulmonary infiltrates in non-HIV immunocompromized patients: a diagnostic approach using non-invasive and bronchoscopic procedures. Thorax 2001; 56: 319–81.
  • Pagano L, Pagliari G, Basso A, Marra R, Sica S, Frigieri L, et al. The role of bronchoalveaolar lavage in the microbiological diagnosis of pneumonia in patients with haematological malignancies. Ann Med 1991; 29: 535–40.
  • de Jaeger A, Litalien C, Lacroix J, Guertin M-C, Infante-Rivard C. Protected specimen brush and bronchoalveolar lavage to diagnose bacterial nosocomial pneumonia in ventilated adults: a meta-analysis. Crit Care Med 1999; 21: 2548–60.
  • Torres A, El-Ebiary M. Bronchoscopic BAL in the diagnosis of ventilator-associated pneumonia. Chest 2000; 111: 198S–202S.
  • Sörensen J, Forsberg P, Håkanson E, Maller R, Sederholm C, Sörén L, Carlsson C. A new diagnostic approach to the patient with severe pneumonia. Scand J Infect Dis 1989; 21: 33–41.
  • Thorpe JE, Baughman RP, Frame PT, Wesseler TA, Staneck JL. Bronchoalveolar lavage for diagnosing acute bacterial pneumonia. J Infect Dis 1981; 155: 855–61.
  • Feinsilver SH, Fein AM, Niederman MS, Schultz DE, Faegenburg DH. Utility of fibreoptic bronchoscopy in non-resolving pneumonia. Chest 1990; 98: 1322–6.
  • Jiménez P, Saldías F, Meneses M, Silva ME, Wilson MG, Otth L. Diagnostic fiberoptic bronchoscopy in patients with community-acquired pneumonia: comparison between bronchoalveolar lavage and telescoping plugged catheter cultures. Chest 1993; 103: 1023–1.
  • Dalhoff K, Braun J, Hollandt H, Lipp R, Wiesmann K-J, Marre R. Diagnostic value of bronchoalveolar lavage in patients with opportunistic and non-opportunistic bacterial pneumonia. Infection 1993; 21: 291–6.
  • Rasmussen TR, Korsgaard J, Møller JK, Sommer T, Kilian M. Quantitative culture of bronchoalveolar lavage fluid in community-acquired lower respiratory tract infections. Resp Med 2001; 95: 885–90.
  • Mahbubani MH, Bej AK, Miller R, Haff L, DiCesare J, Atlas RM. Detection of Legionella with polymerase chain reaction and gene probe methods. Mol Cell Probes 1990; 4: 115–81.
  • Rantakokko-Jalava K, Jalava J. Development of conventional and real-time PCR assays for detection of Legionella DNA in respiratory specimens. J Clin Microbiol 2001; 39: 2904–10.
  • Wakefield AE, Pixley FJ, Banerji S, Sinclair K, Miller RF, Moxon ER, Hopkin JM. Detection of Pneumocystis carinii with DNA amplification. Lancet 1990; 336: 451–3.
  • Demmler GJ, Buffone GJ, Schimbor CM, May RA. Detection of cytomegalovirus in urine from newborns by using polymerase chain reaction DNA amplification. J Infect Dis 1988; 158: 1111–84.
  • Hukkanen V, Rehn T, Kajander R, Sjöroos M, Waris M. Timeresolved fluorometry PCR assay for rapid detection of herpes simplex virus in cerebrospinal fluid. J Clin Microbiol 2000; 38: 3214–8.
  • Waris ME, Toikka P, Saarinen T, Nikkari S, Meurman O, Vainionpää R, et al. Diagnosis of Mycoplasma pneumoniae in children. J Clin Microbiol 1998; 36: 3155–9.
  • Soini H, Skurnik M, Liippo K, Tala E, Viljanen M. Detection and identification of Mycobacteria by amplification of a segment of the gene coding for the 32-kilodalton protein. J Clin Microbiol 1992; 30: 2025–8.
  • Rantakokko-Jalava K, Marjamaki M, Marttila H, Makela L, Valtonen V, Viljanen MK. LCx Mycobacterium tuberculosis assay is valuable with respiratory specimens, but provides little help in the diagnosis of extrapulmonary tuberculosis. Ann Med 2001; 33: 55–62.
  • Janatuinen T, Friberg J, Viljanen MK, Raitakari O, Nuutila P, Vainionpää R, et al. Early impairment of coronary flow reserve is not associated with Chlamydia pneumoniae antibodies. Ann Med 2002; 34: 284–90.
  • Nordström K, Kallings I, Dahnsjö H, Clemens F An outbreak of Legionnaire’s disease in Sweden: report of 68 cases. Scand J Infect Dis 1983; 15: 43–55.
  • Retalis P, Strange C, Harley R. The spectrum of adult adenovirus pneumonia. Chest 1996; 109: 1656–1.
  • Dowell SF, Anderson LJ, Gary HE Jr, Erdman DD, Plouffe JF, File TM Jr, et al. Respiratory syncytial virus is an important cause of community-acquired lower respiratory infection among hospitalized adults. J Infect Dis 1996; 114: 456–62.
  • Vuorinen T, Vainionpää R, Hyypiä T. Five years’ experience of reverse-transcriptase polymerase chain reaction in daily diagnosis of enterovirus and rhinovirus infections. Clin Infect Dis 2003; 31: 452–5.
  • Greenberg SB. Viral respiratory infections in elderly patients and patients with chronic obstructive pulmonary disease. Am J Med 2002; 112: 28S–32S.
  • Wedzicha JA. Exacerbations: aetiology and pathophysiological mechanisms. Chest 2002; 121: 136S–41S.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.