Intravenous ceftriaxone compared with oral doxycycline for the treatment of Lyme neuroborreliosis

References

• Burgdorfer W, Barbour AG, Hayes SF, Benach JL, Grunwaldt E, Davis JP. Lyme disease: a tick-borne spirochetosis?. Science 1982; 216: 1317–9
   PubMed Web of Science ®Google Scholar
• Berglund J, Eitrem R, Ornstein K, Lindberg A, Ringer A, Elmrud H, et al. An epidemiologic study of Lyme disease in southern Sweden. N Engl J Med 1995; 333: 1319–24
   PubMed Web of Science ®Google Scholar
• Bensch J, Olcen P, Hagberg L. Destructive chronic Borrelia meningoencephalitis in a child untreated for 15 y. Scand J Infect Dis 1987; 19: 697–700
   PubMed Web of Science ®Google Scholar
• Steere AC, Malawista SE, Bartenhagen NH, Spieler PN, Newman JH, Rahn DW, et al. The clinical spectrum and treatment of Lyme disease. Yale J Biol Med 1984; 57: 453–64
   PubMed Web of Science ®Google Scholar
• Wormser GP, Nadelman RB, Dattwyler RJ, Dennis DT, Shapiro ED, Steere AC, et al. Practice guidelines for the treatment of Lyme disease. The Infectious Diseases Society of America. Clin Infect Dis 2000; 31(Suppl 1)1–14
   PubMed Web of Science ®Google Scholar
• Dotevall L, Alestig K, Hanner P, Norkrans G, Hagberg L. The use of doxycycline in nervous system Borrelia burgdorferi infection. Scand J Infect Dis Suppl 1988; 53: 74–9
   PubMedGoogle Scholar
• Skoldenberg B, Stiernstedt G, Garde A, Kolmodin G, Carlstrom A, Nord CE. Chronic meningitis caused by a penicillin-sensitive microorganism?. Lancet 1983; 2: 75–8
   PubMed Web of Science ®Google Scholar
• Oschmann P, Dorndorf W, Hornig C, Schafer C, Wellensiek HJ, Pflughaupt KW. Stages and syndromes of neuroborreliosis. J Neurol 1998; 245: 262–72
   PubMed Web of Science ®Google Scholar
• Preac-Mursic V, Wilske B, Schierz G. European Borrelia burgdorferi isolated from humans and ticks: culture conditions and antibiotic susceptibility. Zentralbl Bakteriol Mikrobiol Hyg [A] 1986; 263: 112–8
   PubMedGoogle Scholar
• Ruzic-Sabljic E, Maraspin V, Lotric-Furlan S, Jurca T, Logar M, Pikelj-Pecnik A, Strle F. Characterization of Borrelia burgdorferi sensu lato strains isolated from human material in Slovenia. Wien Klin Wochenschr 2002; 114: 544–50
   PubMed Web of Science ®Google Scholar
• Steere AC, Pachner AR, Malawista SE. Neurological abnormalities of Lyme disease: successful treatment with high-dose intravenous penicillin. Ann Intern Med 1983; 99: 767–72
   PubMed Web of Science ®Google Scholar
• Berglund J, Stjernberg L, Ornstein K, Tykesson-Joelsson K, Walter H. 5-y follow-up study of patients with neuroborreliosis. Scand J Infect Dis 2002; 34: 421–5
   PubMed Web of Science ®Google Scholar
• Ruzic-Sabljic E, Lotric-Furlan S, Maraspin V, Cimperman J, Pleterski-Rigler D, Strle F. Analysis of Borrelia burgdorferi sensu lato isolated from cerebrospinal fluid. APMIS 2001; 109: 707–13
   PubMed Web of Science ®Google Scholar
• Ornstein K, Berglund J, Nilsson I, Norrby R, Bergstrom S. Characterization of Lyme borreliosis isolates from patients with erythema migrans and neuroborreliosis in southern Sweden. J Clin Microbiol 2001; 39: 1294–8
   PubMed Web of Science ®Google Scholar
• Kaiser R. Variable CSF findings in early and late Lyme neuroborreliosis: a follow-up study in 47 patients. J Neurol 1994; 242: 26–36
   PubMed Web of Science ®Google Scholar
• Mullegger RR, Millner MM, Stanek G, Spork KD. Penicillin G sodium and ceftriaxone in the treatment of neuroborreliosis in children: a prospective study. Infection 1991; 19: 279–83
   PubMed Web of Science ®Google Scholar
• Pfister HW, Preac-Mursic V, Wilske B, Schielke E, Sorgel F, Einhaupl KM. Randomized comparison of ceftriaxone and cefotaxime in Lyme neuroborreliosis. J Infect Dis 1991; 163: 311–8
   PubMed Web of Science ®Google Scholar
• Logigian EL, Kaplan RF, Steere AC. Chronic neurological manifestations of Lyme disease. N Engl J Med 1990; 323: 1438–44
   PubMed Web of Science ®Google Scholar
• Dotevall L, Hagberg L. Penetration of doxycycline into cerebrospinal fluid in patients treated for suspected Lyme neuroborreliosis. Antimicrob Agents Chemother 1989; 33: 1078–80
   PubMed Web of Science ®Google Scholar
• Mandell GL, Benett JE, Dolin R. Principles and practice of infectious diseases5th edn. Churchill Livingstone, Philadelphia 2000; 2503
   Google Scholar
• Karlsson M, Hammers-Berggren S, Lindquist L, Stiernstedt G, Svenungsson B. Comparison of intravenous penicillin G and oral doxycycline for treatment of Lyme neuroborreliosis. Neurology 1994; 44: 1203–7
   PubMed Web of Science ®Google Scholar
• Dotevall L, Hagberg L. Successful oral doxycycline treatment of Lyme disease-associated facial palsy and meningitis. Clin Infect Dis 1999; 28: 569–74
   PubMed Web of Science ®Google Scholar
• Thorstrand C, Belfrage E, Bennet R, Malmborg P, Eriksson M. Successful treatment of neuroborreliosis with 10-d regimens. Pediatr Infect Dis J 2002; 21: 1142–5
   PubMed Web of Science ®Google Scholar