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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 30, 2000 - Issue 18
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Original Articles

Ring Contraction Through Epoxide Rearrangement: A Formal Synthesis of Capsorubin

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Pages 3327-3340 | Received 27 Nov 1999, Published online: 04 Dec 2007

References

  • Present address: Núcleo de Biomedicina, Instituto de Pesquisa e Desenvolvimento, Universidade do Vale do Parafba, São José dos Campos -- SP, Brazil.
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  • Isophorone was treated with methylmagnesium bromide and the resulting enolate was rapidly captured with cold acetic acid;11 the double bond was thus shifted to the β,γ-position relative to the ketone (82% yield), and the resulting product was reduced with LiAlH4 to compound 4 (96% yield).12 ,
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  • Zukerman-Schpector , J. results to be published.

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