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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 30, 2000 - Issue 12
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Original Articles

Microwave Heating in Organic Synthesis: Decarboxylation of Malonic Acid Derivatives in Water

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Pages 2099-2104 | Received 10 Jun 1999, Published online: 04 Dec 2007

References and Notes

  • Stinson , S. May 20 1996 . “Use of Microwave Heating to Speed Organic Reactions Continues to Grow” . In Chemical and Engineering News May 20 , 45 – 46 . No. 73
  • A number of commercial manufacturers provide laboratory scale microwave reactors as well as pilot scale designs for industrial needs. Milestone, Inc. of Monroe, CT, Lambda Technologies of Raleigh, NC, Cober Electronics, Inc. of S. Norwalk, CT and CEM of TN are a few examples.
  • Giguere , R. J. 1989 . Organic Synthesis: Theory and Applications , Edited by: Hudlicky , Tomas . Vol. 1 , 103 – 172 . Greenwich, CT : JAI Press .
  • Abramovitch , R. A. 1991 . Org. Prep. Proceed. Int. , 23 : 685
  • Giguere , R. J. 1992 . Mater. Res. Soc. Symp. Proc. , 269 : 3876
  • Mingos , D. M.P. 1994 . Res. Chem. Intermed. , 20 : 85
  • Westaway , K. C. and Gedye , R. N. 1995 . J. Microwave Power Electromag. Energy , 30 : 219
  • Strauss , C. R. and Trainor , R. W. 1995 . Aust. J. Chem. , 48 : 1665
  • Majetich , G. F. and Wheless , K. 1997 . Microwave-Enhanced Chemistry , 455 – 505 . ACS Publications . (This last review documents microwave work prior to Spring, 1993)
  • Goldberg , D. R. , Hansen , J. A. and Giguere , R. J. 1993 . Tetrahedron Lett. , 34 : 8003
  • Brodney , M. A. , O'Leary , J. P. , Hansen , J. A. and Giguere , R. J. 1995 . Synth. Commun. , 25 : 521
  • The Ethos microwave reactor is produced by Milestone, Inc., 160B Shelton Road, Monroe, CT. 06408.
  • Presented in part by RJG at the 33rd Microwave Power Symposium . July 12–15 , Chicago.
  • Loupy , A. , Pigeon , P. , Ramdani , M. and Jacquault , P. 1993 . J. Chem. Research(S) , : 36 For related work on decarboxylations of organic compounds using microwaves, see
  • Jones , G. B. and Chapman , B. J. 1993 . J. Org. Chem. , 58 : 5558 For other microwave organic reactions conducted in water, confer Ref. 3f above, pp. 1684–1687
  • Weflon is a patented Milestone telfon polymer loaded with particulite carbon that facilitates its coupling with microwaves.

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