Microwave‐Assisted One‐Pot Synthesis of 2‐(Substituted phenyl)‐1H‐benzimidazole Derivatives

References

• Navarrete‐Vázquez , G. , Yepez‐Mulia , L. , Hernández‐Campos , A. , Tapia , A. , Hernández‐Luis , F. , Cedillo , R. , González , J. , Martínez‐Fernández , M. , Martínez‐Grueiro , M. and Castillo , R. 2003 . Synthesis and antiparasitic activity of albendazole and mebendazole analogues . Bioorg. Med. Chem. , 11 : 4615 – 4622 .
   PubMed Web of Science ®Google Scholar
• Özden , S. , Atabey , D. , Yıldız , S. and Göker , H. 2005 . Synthesis and potent antimicrobial activity of some novel methyl or ethyl 1H‐benzimidazole‐5‐carboxylates derivatives carrying amide or amidine groups . Bioorg. Med. Chem. , 13 : 1587 – 1597 .
   PubMed Web of Science ®Google Scholar
• Andrzejewska , M. , Yépez‐Mulia , L. , Cedillo‐Rivera , R. , Tapia , A. , Vilpo , L. , Vilpo , J. and Kazimierczuk , Z. 2002 . Synthesis, antiprotozoal and anticancer activity of substituted 2‐trifluoromethyl‐ and 2‐pentafluoroethylbenzimidazoles . Eur. J. Med. Chem. , 37 : 973 – 978 .
   PubMed Web of Science ®Google Scholar
• Terzioglu , N. , van Rijn , R. , Bakker , R. A. , De Esch , I. J. P. and Leurs , R. 2004 . Synthesis and structure–activity relationships of indole and benzimidazole piperazines as histamine H4 receptor antagonists . Bioorg. Med. Chem. Lett. , 14 : 5251 – 5256 .
   PubMed Web of Science ®Google Scholar
• Mavandadi , F. and Lidström , P. 2004 . Microwave‐assisted chemistry in drug discovery . Curr. Top. Med. Chem. , 4 : 773 – 792 .
   PubMed Web of Science ®Google Scholar
• Navarrete‐Vázquez , G. , Cedillo , R. , Hernández‐Campos , A. , Yepez‐Mulia , L. , Hernández‐Luís , F. , Valdez , J. , Morales , R. , Cortes , R. , Hernandez , M. and Castillo , R. 2001 . Synthesis and antiparasitic activity of 2‐(trifluoromethyl)‐benzimidazole derivatives . Bioorg. Med. Chem. Lett. , 11 : 187 – 190 .
   PubMed Web of Science ®Google Scholar
• Göker , H. , Ku , C. , Boykin , D. W. , Yildiz , S. and Altanar , N. 2002 . Synthesis of some new 2‐substituted‐phenyl‐1H‐benzimidazole‐5‐carbonitriles and their potent activity against Candida species . Bioorg. Med. Chem. , 10 : 2589 – 2596 .
   PubMed Web of Science ®Google Scholar
• Ben‐Alloum , A. , Bakkas , S. and Soufiaoui , M. 1998 . Benzimidazoles: Oxydation hétérocyclisante par le nitrobenzène ou le diméthylsulfoxyde sur silice et sous irradiation micro‐ondes ou ultra‐violet . Tetrahedron Lett. , 39 : 4481 – 4384 .
   Web of Science ®Google Scholar
• Verner , E. , Katz , B. A. , Spencer , J. R. , Allen , D. , Hataye , J. , Hruzewicz , W. , Hui , H. C. , Kolesnikov , A. , Li , Y. , Luong , C. , Martelli , A. , Radika , K. , Rai , R. , She , M. , Shrader , W. , Sprengeler , P. A. , Trapp , S. , Wang , J. , Young , W. B. and Mackman , R. L. 2001 . Development of serine protease inhibitors displaying a multicentered short (<2.3 A) hydrogen bond binding mode: Inhibitors of urokinase‐type plasminogen activator and factor Xa . J. Med. Chem. , 44 : 2753 – 2771 .
   PubMed Web of Science ®Google Scholar
• Lombardy , R. L. , Tanious , F. A. , Ramachandran , K. , Tidwell , R. R. and Wilson , W. D. 1996 . Synthesis and DNA interactions of benzimidazole dications which have activity against opportunistic infections . J. Med. Chem. , 39 : 1452 – 1462 .
   PubMed Web of Science ®Google Scholar
• Lin , S. and Yang , L. 2005 . A simple and efficient procedure for the synthesis of benzimidazoles using air as the oxidant . Tetrahedron Lett. , 46 : 4315 – 4319 .
   Web of Science ®Google Scholar
• Estrada‐Soto , S. , Villalobos‐Molina , R. , Aguirre‐Crespo , F. , Moreno‐Díaz , H. , Torres‐Piedra , M. and Navarrete‐Vázquez , G. 2006 . Relaxant activity of 2‐(substituted phenyl)‐1H‐benzimidazoles on isolated rat aortic rings: Design and synthesis of 5‐nitro derivatives . Life Sci. , 79 : 430 – 435 .
   PubMed Web of Science ®Google Scholar
• Navarrete‐Vázquez , G. , Moreno‐Díaz , H. , Aguirre‐Crespo , F. , León‐Rivera , I. , Villalobos‐Molina , R. , Muñoz‐Muñiz , O. and Estrada‐Soto , S. 2006 . Design, microwave‐assisted synthesis, and spasmolytic activity of 2‐(alkyloxyaryl)‐1H‐benzimidazole derivatives as constrained stilbene bioisosteres . Bioorg. Med. Chem. Lett. , 16 : 4169 – 4173 .
   PubMed Web of Science ®Google Scholar
• Moreno‐Díaz , H. , Navarrete‐Vázquez , G. , Estrada‐Soto , S. and Tlahuext , H. 2006 . 2‐(4‐Methoxyphenyl)‐1H‐benzimidazole . Acta Cryst. , E62 : o2601 – o2602 .
   Google Scholar