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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 37, 2007 - Issue 20
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Original Articles

Tandem Ring Opening and Oximation of Ethyl 3‐Aroyl‐1‐cyano‐4‐hydroxy‐2,4,6‐triarylcyclohexanecarboxylate by Hydroxylamine

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Pages 3635-3648 | Received 13 Mar 2007, Published online: 05 Oct 2007

References

  • Strupczewski , J. T. , Allen , R. C. , Gardner , B. A. , Schmid , B. L. , Stache , U. , Glamkowski , E. J. , Jones , M. C. , Ellis , D. B. , Huger , F. P. and Dunn , R. W. 1985 . Synthesis and neuroleptic activity of 3‐(1‐substituted‐4‐piperidinyl)‐1,2‐benzisoxazoles . J. Med. Chem. , 28 : 761 – 769 .
  • Davis , L. , Effland , R. C. , Klein , J. T. , Dunn , R. W. , Geyer , H. M. and Petko , W. W. 1992 . 3‐substituted‐1,2‐benzisoxazoles: novel antipsychotic agents . Drug Des. Discov. , 8 : 225 – 240 .
  • Saunders , J. C. and Williamson , W. R. N. 1979 . Potential antiinflammatory compounds, 2: Acidic antiinflammatory 1,2‐benzisoxazoles . J. Med. Chem. , 22 : 1554 – 1558 .
  • Naruto , S. , Mizuta , H. , Sawayama , T. , Yoshida , T. , Uno , H. , Kawashima , K. , Sohji , Y. , Kadokawa , T. and Nishimura , H. 1982 . Synthesis and spasmolytic activities of 2‐(1,2‐benzisoxazol‐3‐yl)‐3{[ω´‐(dialkylamino)alkoxy]phenyl}acrylonitriles . J. Med. Chem. , 25 : 1240 – 1245 .
  • Vandenheuvel , W. J. , Arison , B. H. , Miller , T. W. , Kulsa , P. , Eskola , P. , Mrozik , H. , Miller , A. K. , Skeggs , H. , Zimmerman , S. B. and Miller , B. M. 1979 . Urinary metabolites of 3a,4,5,6,7,7a–hexahydro‐3‐(1‐methyl‐5‐nitro‐1H‐imidazol‐2‐yl)‐1,2‐benzisoxazole in the dog . J. Pharm. Sci. , 68 : 1156 – 1158 .
  • Kalkote , U. R. and Goswami , D. D. 1977 . Aust. J. Chem. , 30 : 1847
  • Falch , E. , Perregaard , J. , Frolund , B. , Sokilde , B. , Buur , A. , Hansen , L. M. , Frydenvang , K. , Brehm , L. , Bolvig , T. , Larsson , O. M. , Sanchez , C. , White , H. S. , Schousboe , A. and Krogsgaard‐Larsen , P. 1999 . Selective inhibitors of glial GABA uptake: Synthesis, absolute stereochemistry, and pharmacology of the enantiomers of 3‐hydroxy‐4‐amino‐4,5,6,7‐tetrahydro‐1,2‐benzisoxazole (exo‐THPO) and analogues . J. Med. Chem. , 42 : 5402 – 5414 .
  • Soto , J. L. , Seoane , C. , Mansilla , A. M. and Pardo , M. C. 1981 . On the reaction of chalcone with ethyl cyanoacetate . Tetrahedron Lett. , 22 : 4845 – 4848 .
  • 2004. Hyperchem 7.0. Hypercube Inc., Gainsville, FL, USA http://www.hyper.com/
  • Stewart , J. J. P. 1990 . Semiempirical Molecular Orbital Methods, Reviews in Computational Chemistry Edited by: Lipkowitz , K. B. and Boyd , D. B. Vol. 1 , 45 Weinheim : VCH .
  • Sheldrick , G. M. 1990 . Phase annealing in SHELX‐90: Direct methods for larger structures . Acta Cryst. , A46 : 467 – 473 .
  • Sheldrick , G. M. 1997 . “ SHELXL97 ” . Germany : University of Gottingen .
  • Darwish , A. I. 2002 . Reactivity of some cyclohexanol derivatives towards sodium ethoxide in ethanol . Egypt. J. Chem. , 45 : 695 – 711 .
  • Al‐Arab , M. M. , Ghanem , B. S. and Fitton , A. O. 1989 . A unique trimolecular Michael reaction and cyclization . Tetrahedron , 45 : 6545 – 6452 .

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