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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 41, 2011 - Issue 9
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Original Articles

Recyclable Siloxy Serine Organocatalyst for the Direct Asymmetric Mannich Reactions in Ionic Liquids

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Pages 1293-1300 | Received 03 Nov 2009, Published online: 30 Mar 2011

REFERENCES

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  • (a) Kotrusz , P. ; Kimentova , I. ; Gotov , B. ; Toma , S. ; Solcaniova , E. Proline-catalyzed asymmetric aldol reaction in room temperature ionic liquid [bmim]PF6 . Chem. Commun . 2002 , 2510 ; (b) Loh , T. P. ; Feng , L. C. ; Yang , H. Y. ; Yang , J. Y. I-Proline in an ionic liquid as an efficient and reusable catalyst for direct asymmetric aldol reactions . Tetrahedron Lett. 2002 , 43 , 8741 ; (c) Córdova , A. Direct catalytic asymmetric cross-aldol reactions in ionic liquid media . Tetrahedron Lett. 2004 , 45 , 3949 ; (d) Miao , W. ; Chan , T. H. Ionic-liquid-supported organocatalyst: Efficient and recyclable ionic-liquid-anchored proline for asymmetric aldol reaction . Adv. Synth. Catal. 2006 , 348 , 1711 ; (e) Ni , B. ; Zhang , Q. ; Headley , A. D. Functionalized chiral ionic liquid as recyclable organocatalyst for asymmetric Michael addition to nitrostyrenes . Green Chem. 2007 , 9 , 737 ; (f) Zhou , L. ; Wang , L. Chiral ionic liquid containing L-proline unit as a highly efficient and recyclable asymmetric organocatalyst for aldol reaction . Chem. Lett. 2007 , 36 , 628 .
  • (a) Teo , Y. C. Direct asymmetric aldol reactions catalyzed by a siloxy serine organocatalyst in water . Tetrahedron: Asymmetry 2007 , 18 , 1155 ; (b) Teo , Y. C. ; Lau , J. J. ; Wu , M. C. Direct asymmetric three-component Mannich reactions catalyzed by a siloxy serine organocatalyst in water . Tetrahedron: Asymmetry 2008 , 19 , 186 ; (c) Teo , Y. C. ; Chua , G. L. A recyclable non-immobilized siloxy serine organocatalyst for the asymmetric direct aldol reaction . Tetrahedron Lett. 2008 , 49 , 4235 ; (d) Teo , Y. C. ; Peter , L. P. F. Organic solvent-free direct asymmetric aldol reactions catalyzed by a siloxy serine organocatalyst in brine . Synth. Commun. 2009 , 39 , 3081 ; (e) Teo , Y. C. ; Chua , G. L. ; Ong , C. Y. ; Poh , C. Y. Organocatalytic asymmetric syn-selective direct aldol reaction in water . Tetrahedron Lett. 2009 , 50 , 4854 .

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