Publication Cover
Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 41, 2011 - Issue 15
263
Views
5
CrossRef citations to date
0
Altmetric
Original Articles

Studies Towards the Synthesis of ATP Analogs as Potential Glutamine Synthetase Inhibitors

, &
Pages 2216-2225 | Received 10 Dec 2009, Published online: 25 May 2011

REFERENCES

  • Hugonnet , J.-E. ; Blanchard , J. S. Irreversible inhibition of the Mycobacterium tuberculosis β-lactamase by clavulanate . Biochemistry 2007 , 46 , 11998 – 12004 .
  • Espinal , M. A. The global situation of MDR-TB . Tuberculosis 2003 , 83 , 44 – 51 .
  • WHO . Emergence of XDR-TB . Available at http://www.who.int/mediacentre/news/notes/2006/np23/en/
  • Shah , N. S. ; Pratt , R. ; Althomsons , S. ; Navin , T. ; Castro , K. G. ; Robison , V. A. ; Cegielski , J. P. Extensively drug-resistant tuberculosis, United States, 1993–2006 . JAMA 2007 , 297 ( 17 ), 1871 – 1873 .
  • Shen , X. ; Shen , G.-M. ; Wu , J. ; Gui , X.-H. ; Li , X. ; Mei , J. ; DeRiemer , K. ; Gao , Q. Association between embB codon 306 mutations and drug resistance in Mycobacterium tuberculosis . Antimicrob. Agents Chemother. 2007 , 51 , 2618 – 2620 .
  • Beers , M. H. ; Berkow , R. The Merck Manual of Diagnosis and Therapy, , 7th ed. ; Merck & Co. : Whitehouse Station , NJ , 1999 ; p. 1193 .
  • Yong , K. J. ; Shakow , A. ; Mate , K. ; Vanderwarker , C. ; Gupta , R. ; Farmer , P. Limited good and limited vision: Multidrug-resistant tuberculosis and global health policy . Soc. Sci. Med. 2005 , 61 ( 4 ), 847 – 859 .
  • Hirschfield , G. R. ; McNeil , M. ; Brennan , P. J. Peptidoglycan-associated polypeptides of Mycobacterium tuberculosis . J. Bacteriol. 1990 , 172 ( 2 ), 1005 – 1013 .
  • Gxoyiya , B. S. B. ; Kaye , P. T. ; Kenyon , C. Benzimidazole-derived ATP analogues as potential glutamine synthetase inhibitors . Synth. Commun. 2009 , 39 ( 15 ), 2723 – 2736 .
  • Mutorwa , M. ; Salisu , S. ; Blatch , G. L. ; Kenyon , C. ; Kaye , P. T. 3-Substituted anilines as scaffolds for the construction of glutamine synthetase and DXP-reductoisomerase inhibitors . Synth. Commun. in press .
  • Furniss , B. S. ; Hannaford , A. J. ; Smith , P. W. G. ; Tatchell , A. R. Vogel's Textbook of Practical Organic Chemistry, , 5th ed. ; Longman Scientific and Technical : New York , 1989 ; pp. 644 – 645 .
  • Kraybill , B. C. ; Elkin , L. L. ; Blethrow , J. D. ; Morgan , D. O. ; Shokat , K. M. Inhibitor scaffolds as new allele specific kinase substrates . J. Am. Chem. Soc. 2002 , 124 ( 41 ), 12118 – 12128 .
  • Hussain , A. ; Rytting , J. H. Prodrug approach to enhancement of rate of dissolution of allopurinol . J. Pharm. Sci. 1974 , 63 ( 5 ), 798 – 799 .
  • Tan , K. L. ; Vasudevan , A. ; Bergman , R. G. ; Ellman , J. A. ; Souers , A. J. Microwave-assisted C-H bond activation: A rapid entry into functionalized heterocycles . Org. Lett. 2003 , 5 ( 12 ), 2131 – 2134 .
  • (a) Kaye , P. T. ; Musa , M. A. Application of Baylis–Hillman methodology in the synthesis of coumarin derivatives. Synth. Commun. 2003, 33(10), 1755–1770; (b) Kaye , P. T. ; Musa , M. A. A convenient and improved Baylis–Hillman synthesis of 3-substituted 2H-1-benzo-pyran-2-ones. Synthesis 2002, 18, 2701–2706; (c) Kaye , P. T. ; Musa , M. A. ; Nocanda , X. W. Efficient and chemoselective access to 3-(chloromethyl)coumarins via direct cyclization of unprotected Baylis–Hillman adducts. Synthesis 2003, 4, 531–534.
  • Stanley , W. L. ; Jurd , L. J. Citrus coumarins . Agric. Food Chem. 1971 , 19 ( 6 ), 1106 – 1110 .
  • Bashiardes , G. ; Safir , I. ; Barbot , F. ; Laduranty , J. A new method for the synthesis of plurisubstituted pyrroles. Tetrahedron Lett. 2003 , 44 , 8417 – 8420 .
  • Musa , M. A. Applications of Baylis–Hillman reaction in the synthesis of coumarin derivatives. PhD thesis , Rhodes University , 2002 .
  • Lee , Y.-C. Studies towards the development of novel HIV-1 integrase inhibitors. MSc thesis , Rhodes University , 2009 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.