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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 16, 1986 - Issue 5
69
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Original Articles

Facile Synthesis of Alkylthiobenzaldehydes

Pages 565-570 | Published online: 19 Dec 2006

References

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  • Although secondary and tertiary mercaptans provide excellent yields of the ortho-alkyltho substituted benzaldehydes with 2-bromobenzaldehyde, the use of the alkoxy substituted bromobenzaldehydes affords mixture of the desired products and dehalogenated starting materials.
  • In the caes of 4,5-methylenedioxy-2-bromobenzaldehyde (1d), cleavage of the methlenedioxy ether was the major pathway.
  • Ketones react in a similar fashion. Unpublished results from these laboratories.
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