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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 17, 1987 - Issue 5
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Original Articles

A Simple Synthesis of 2-(1-Hydroxyalkyl)acrylonitriles

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Pages 587-591 | Published online: 05 Dec 2006

References

  • Hoffmann , H. M.R. 1985 . J. Rabe, J. Org. Chem , 50 : 3849
  • Hoffmann , H. M.R. 1984 . J. Rabe, Helv. Chim. Acta , 67 : 413
  • Hoffmann , H. M.R. 1983 . J. Rabe, Angew. Chem. Int. Ed. Engl , 22 : 795
  • Basavaiah , D. and Gowriswari , V. V.L. 1986 . Tetrahedron Lett , 27 : 2031
  • Sato , S. , Matsuda , I. and Izumi , Y. 1985 . Chem. Lett , : 1875
  • Irnagawa , T , Uemura , K. , Nagai , Z. and Kawanisi , H. 1984 . Syn. Cornrnun , 14 : 1267 One interesting report for the synthesis of 2-(1-Hydroxyalkyl)acrylonitriles has appeared recently where these molecules are prepared from acrylonitrile and aldehydes by using tributylphosphine, triethylaluminium
  • Amri , H. and Villieras , J. 1986 . Tetrahedron Lett , 27 : 4307 After we completed our studies, a similar report has appeared for the preparation of 2-(hydroxyalkyl)acrylonitriles
  • The first step in this catalytic cycle may involve the conjugate addition of DABCO to acrylonitrile followed by the addition to the aldehyde
  • Bormann , C. , Huhn , W. , Zähner , H. , Rathmann , R. , Hahn , H. and König , W. A. 1985 . J. Antibiotics , 38 : 9

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