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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 19, 1989 - Issue 3-4
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Original Articles

A mild and Selective Method of Ester Hydrolysis

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Pages 627-631 | Received 02 Aug 1988, Published online: 23 Oct 2006

References

  • Euranto , E. K. 1969 . The chemistry of Carboxylic Acids and Esters Edited by: Patai , S. London : Interscience Publishers . in: (ed.)
  • Dean , P. D. G. 1965 . J. Chem. Soc. , : 6655
  • Krapcho , A. P. 1982 . Synthesis , : 805 – 893 .
  • Bigley , D. B. 1964 . J. Chem. Soc. , : 3897
  • Ranu , B. C. and Sarkar , D. C. 1988 . J. Org. Chem. , 53 : 878
  • Although use of ion-exchange resins for hydrolysis of simple esters in connection with their physical (kinetic) studies has been reported6 long back, the potentiality of this reagent for preparative purposes has never been studied.
  • Bernhard , S. A. , Garfield , A. and Hammet , L. P. 1954 . J. Am. Chem. Soc. , 76 : 991 – 992 .
  • Astle , J. and Oscar , J. A. 1961 . J. Org. Chem. , 26 : 1713 and references cited therein.
  • Dowex-50 (Fluka) was soaked in 4N HCl overnight and then washed with distilled water until acid-free (tested with AgNO3 solution) and used in moist form.
  • Ghatak , U. R. , Banerjee , A. K. and Chakravorty , J. 1968 . Tetrahedron , 24 : 1577
  • The used Dowex-50 after being washed with methanol and water can be recycled after regeneration.

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