References
- The present address is Pharmaceutical Research Laboratories, Kyowa Hakko Kogyo Co., Ltd., 1188 Shimotogari, Nagaizumi, Sunto, Shizuoka 411, Japan.
- Carter , S. K. and Crook , S. T. , eds. 1979 . Mitomycin C: Current Status and New Developments , New York : Academic Press .
- Shirahata , K. , Morimoto , M. , Ashizawa , T. , Mineura , K. , Kono , M. , Saitoh , Y. and Kasai , M. 1981 . The 21st Interscience Conference on Antimicrobial Agents and Chemotherapy . Nov. 1981 , Chicago. pp. 421 Abstracts
- Urakawa , C. , Tsuchiya , H. and Nakano , K. 1981 . J. Antibiot. , 34 : 243
- Urakawa , C. , Tsuchiya , H. , Nakano , K. and Nakamura , N. 1981 . J. Antibiot. , 34 : 1152
- The overall yield of mitomycin G 2 from mitomycin B 5 was 4.6 % according to the precedent literature.4
- The compound 7 afforded a small amount of 2 (11 %) and two byproducts which had lower polarity than 2 and might be methylated at not only the 9a-hydroxy but also the 7-amino groups. This implied the generation of anion at the nitrogen of the 7th position by the treatment with sodium hydride. Similar results have been reported by others.7
- Kaneko , T. , Wong , H. and Doyle , T. W. 1985 . Tetrahedron Lett. , 26 : 3923