synthesis of Enantiomerically Pure amino acids containing a 2-Amino-4-thiazolyl side chain

References

• Ochlai , M. , Morimuto , A. , Okuda , T. , Matsushita , Y. , Yamamoto , H. , Akiand , O. and Koda , M. 1980 . J. Antibiotics , 33 : 1022
   PubMedGoogle Scholar
• Silberg , A. , Ruse , M. , Mantsch , H. and Csontos , S. 1964 . Chem Ber , 97 : 1767
   Google Scholar
• Sprague , J. , Hand , A. and Ziegler , C. 1946 . J Amer Chem Soc , 68 : 2155
   PubMedGoogle Scholar
• O'Donnell , M. , Bennett , W. and Wu , S. 1989 . J Amer Chem Soc , 111 : 2353
   Web of Science ®Google Scholar
• Schollkopf , U. , Hartwig , W. and Groth , U. 1979 . Angew Chem Int Ed , 18 : 863
   Google Scholar
• Jackson , R. , James , K. , Wythes , M. and Wood , A. 1989 . J Chem Soc Chem Comm , : 644
   Google Scholar
• Sham , H. , Stein , H. and Cohen , J. 1987 . J Chem Soc Chem Comm , : 1792
   Google Scholar
• The derivatives were purchased from Bachem Inc
   Google Scholar
• Balaspiri , L. , Penke , B. , Papp , Gy. , Dombi , Gy. and Kovacs , K. 1975 . Helv Chem Acta , 58 : 969
   PubMedGoogle Scholar
• The crude chloroketone contains a variable amount of the β-methyl ester (from 25–50%), produced during the diazomethane reaction. This material was easily removed, at the final product stage, either by recrystallization (method A, Table 1) or chromatographically (method B, Table 1)
   Google Scholar