Preparation of (-)-(1R, 2S)-1-Phenylpropane-1,2-Diol by Fermenting Baker's Yeast Reduction of 1-Phenyl-1,2-propanedione

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• 1H nmr (100 MHz, CDCl3/TMS, δ in ppm) δ 1.01 (d, J = 7.0 Hz, 3H, CH3), 2.80 (br, s, 2H, OH), 3.95 (m, 1H, CHCH3), 4.63 (d, J ‐ 4.0 Hz, 1H, PhCH), 7.31 (s, 5H, Ph); IR (KBr) 3400, 3090, 2900, 1610, 1500, 1455, 1390, 1205, 1130, 1080, 1045, 995, 855, 750, 710 cm‐1; MS (70 eV), m/z (relative intensity) 108(100), 79(98), 45(26)
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• 1H nmr (80 MHz, CDCl3/TMS, δ in ppm) δ 1.40 (d, J = 6.0, 3H, CH3), 5.40—5.75 (m, 1H, CHCH3), 6.30 (d, J = 4.0, 1H, PhCH), 7.18–7.60 (m, 11H, aromatics), 7.88–8.18 (m, 4H, aromatics); IR (KBr) 3080, 3060, 3030, 2990, 2920, 1710, 1600, 1450, 1315, 1295, 1275, 1250, 1110, 1070, 1025, 710 cm‐1
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