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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 20, 1990 - Issue 10
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Original Articles

A Synthesis of 2-Alkyl and 2-Benzyl Substituted Acrylonitriles from 2-Alkyl and 2-Benzylidene Cyanoacetate Esters under Mild Conditions

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Pages 1463-1468 | Received 19 Feb 1990, Published online: 24 Oct 2006

References

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  • Grieco , P. A. and Hiroi , K. 1972 . J. Chem. Soc. Chem. Commun. , : 1317 Grieco, P. A., and Hiroi, K. Tetrahedron Lett. 1973, 1831. c) McGraw, W. J. U.S. Patent 2624723; C. A. 1953, 47, 11232.
  • Lucast , D. H. and Wemple , J. 1976 . Synthesis , : 724
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  • Bianco , A. , Passacantilli , P. and Righi , G. 1988 . Synth. Commun. , 18 : 1765 The use of phosphate buffer was necessitated by the facile saponification of cyanoacetate esters under mildly basic conditions.
  • Satisfactory high field NMR, IR, and chemical ionization mass spectra (CIMS) or fast atom bombardment mass spectra (FABMS) were obtained for compounds 4a- f and 5a-f
  • Ono , N. , Yoshimura , T. , Saito , T. , Tamura , R. , Tanikaga , R. and Kaji , A. 1979 . Bull. Chem. Soc. Jpn. , 52 : 1716
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