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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 20, 1990 - Issue 16
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Original Articles

Synthesis of Trans-Carah-4-Carboxylic Acids

, &
Pages 2507-2517 | Received 15 Jun 1990, Published online: 24 Oct 2006

References

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  • IUPAC nomenclature has not been used. Prefixes “cis” and “trans” define the relative stereochemistry of both methyl group and the substituent at C-4 with respect to the cyclopropane ring
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  • It was assumed that 4-methylenecaranes 8 and 9 adopt the conformations preferred for the corresponding ketones 6 and 7
  • Unpublished results
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  • The specific rotation of alcohol 10 could not be measured because we were unable to obtain a pure sample. Since a very small value of optical rotation can be predicted (see Table), the measurement of the specific rotation on an impure sample would have been meaningless

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