Publication Cover
Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 22, 1992 - Issue 13
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Original Articles

The Alkylation of 3-Chloro-2-cyclohexenones

Pages 1959-1966 | Received 04 Mar 1992, Published online: 23 Sep 2006

References

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  • Wender , P. A. and Eck , S. L. 1977 . Tetrahedron Letters. , : 1245 (spiroalkanes)
  • Clark , R. D. and Heathcock , C. H. 1976 . J. Org. Chem. , 41 : 636 (cyclohexenones)
  • Chorvat , R. J. , Palmer , J. R. and Papo , R. 1978 . J. Org. Chem. , 43 : 966 (steroids)
  • Audenaert , F. , De Keukeleire , D. and Vandewalle , M. 1987 . Tetrahedron. , 43 : 5509 (daucene)
  • Berchtold , G. A. and Braun , A. G. 1989 . J. Org. Chem. , 54 : 2787 (benzene diol epoxides)
  • Mewshaw , R. E. 1989 . Tetrahedron Letters. , 30 : 3753 The chlorocyclohexenones described herein were prepared by the method of
  • Larock , R. C. 1989 . Comprehensive Organic Transformations , 375 New York, N.Y. : VCR Publishers . lists 19 references to 8 different reagents for the conversion of cyclohexane-1,3-diones into 3-chloro-2-cyclohexen-1-ones
  • Piers , E. , Grierson , J. R. , Lau , C. K. and Nagakura , I. 1982 . Can. J. Chem. , 60 : 210 In a related reaction, the conversion of 4-alkyl-1,3-cyclohexanediones to 6-alkyl-3-iodo-2-cyclohexen-1-ones with Ph3PI2, regioselectivity was high for large alkyl groups
  • Stork , G. and Hudrlik , P. F. 1968 . J. Am. Chem. Soc. , 90 : 4464
  • Patterson , J. W. 1986 . J. Heterocvclic Chem. , 23 : 1689 An example of specific monoalkylation when n-butyllithium was used as a base and which gave dialkylation when LDA was used as a base was observed in 1,4-dihydropyridine chemistry
  • Danheiser , R. L. and Stork , G. 1973 . J. Org. Chem. , 38 : 1775
  • Blagbrough , I. S. and Pattenden , G. 1982 . Tetrahedron Letters. , 23 : 4843
  • Eschenmoser , A , Schreiber , J. and Julia , S. A. 1953 . Helv. Chim. Acta. , 36 : 482 Enol ether 12 is readily available by the method of
  • Tamura , Y. , Kato , S. , Yoshimura , Y. , Nishimura , T. and Kita , Y. 1974 . Chem. Pharm. Bull. , 22 : 1291

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