A Highly Efficient Preparation of N^G-Methyl-L-Arginine and N^G-Methyl-D-arginine

References

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• When the oil shows a light green color, the NMA acetate salt in hot ethanol solution is decolorized with activated carbon then filtered through Celite
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• The spectral properties of the product are in full agreement with those expected. In particular the 1H NMR (D2O) spectrum shows δ 1.65 (m, 2 H), 1.82–1.95 (2 H), 1.88 (s, 3 H), 2.79 (s, 3 H), 3.21 (t, J=6.9 Hz, 2 H), 3.73 (t, J=6.0 Hz, 1 H) with no impurity peaks
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