An Improved Procedure for the Cyanation of Aryl Triflates: A Convenient Synthesis of 6-Cyano-1,2,3,4-Tetrahydroisoquinoline

References

• Dyke , S. F. and Kinsman , R. G. 1981 . “Properties And Reactions Of Isoquinolines And Their Hydrogenated Derivatives” . In Heterocyclic Compounds , Edited by: Grethe , Guenter . Vol. 38 , 170 – 182 . New York : Wiley .
   Google Scholar
• Buck , J. S. 1934 . J. Am. Chem. Soc. , 56 : 1769
   Google Scholar
• Takagi , K. , Sasaki , K. and Sakakibara , Y. 1991 . Bull. Chem. Soc. Jap. , 64 : 1118
   Web of Science ®Google Scholar
• Takagi , K. and Sakakibara , Y. 1989 . Chemistry Letters , : 1957
   Google Scholar
• Chambers , M. R. I. and Widdowson , D. A. 1989 . J. Chem. Soc. Perkin Trans. , I : 1365
   Google Scholar
• Desmond , R. , King , A. O. , Fortin , M. C. , Tschean , D. M. , Pipkik , B. , King , S. and Verhoeven , T. R. 1994 . Synth. Commun. , 24 ( 6 ) : 887
   Web of Science ®Google Scholar
• The use of 0.5 equivalents of Zn(CN)2 was insufficient for complete consumption of the aryl triflate. The use of one equivalent of Zn(CN)2 did not result in an improved yield over 0.7 equivalents. Similar results were obtained in the aryl bromide case (reference 5)
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