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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 26, 1996 - Issue 16
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Original Articles

One-Pot Preparation of 1,3-Dihydro-1-(trifluoromethyl)isobenzofuran-1-ol Derivatives from 1,2-Dibromobenzene

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Pages 3127-3135 | Received 22 Mar 1996, Published online: 21 Aug 2006

References

  • Welch , J. T. 1987 . Tetrahedron , 43 : 3123
  • Begue , J.-P. and Delpon , D. B. 1991 . Tetrahedron , 47 : 3207
  • Nair , H. K. , Lee , K. and Quinn , D. M. 1993 . J. Am. Chem. Soc. , 115 : 9939 – 41 .
  • The strong electron-withdrawing nature of the trifluoromethyl group forces the equilibrium to lie on the side of the cyclic 1,3-dihydro-1-(trifluoromethyl)isobenzofuran-1-ol. The equilibrium is also under the influence of other structural features, such as lactol ring size
  • Becker , D. P. and Flynn , D. L. 1996 . SynLett , : 57 – 59 .
  • Clark , R. D. and Jahangir , A. 1995 . Org. React. , 47 : 1 For a comprehensive review of lateral lithiation see
  • Prabhu , U. D. G. , Eapen , K. C. and Tamborski , C. 1984 . J. Org. Chem. , 49 : 2792

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