The Preparation of 2-Hydroxyethyl-2,3-dihydro-2h-1,4-benzoxazin-3(4h)-one Derivatives

References

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• In all cases, the products obtained after the crude workup were sufficiently pure to carry on as synthetic intermediates. Analytically pure material could be isolated after a single crystallization or trituration step. Yields shown reflect product obtained after purification at each step with, typically, only one crop collected following a crystallization or trituration procedure. Also, with the exception of the parent system ring (ie., 2a), product yields were the result of a single trial
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• Details of the structure activity relationships will be available in a manuscript which is in preparation
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