Effects of fisetin on ethanol-induced rewarding properties in mice

References

• White AM, Orosz A, Powell PA, Koob GF. Alcohol and aging – an area of increasing concern. Alcohol. 2023;107:19–27. doi:10.1016/j.alcohol.2022.07.005.
   PubMed Web of Science ®Google Scholar
• Abrahao KP, Chancey JH, Chan CS, Lovinger DM. Ethanol-sensitive pacemaker neurons in the mouse external globus pallidus. Neuropsychopharmacology. 2017;42:1070–81. doi:10.1038/npp.2016.251.
   PubMed Web of Science ®Google Scholar
• Agarwal K, Luk JW, Manza P, McDuffie C, To L, Jaime-Lara RB, Stangl BL, Schwandt ML, Momenan R, Goldman D, et al. Chemosensory alterations and impact on quality of life in persistent alcohol drinkers. Alcohol Alcohol. 2023;58:84–92. doi:10.1093/alcalc/agac047.
   PubMed Web of Science ®Google Scholar
• Yunusoğlu O. Resveratrol impairs acquisition, reinstatement and precipitates extinction of alcohol-induced place preference in mice. Neurol Res. 2021;43:985–94. doi:10.1080/01616412.2021.1948749.
   PubMed Web of Science ®Google Scholar
• Singh, J. Analysis of fractional blood alcohol model with composite fractional derivative. Chaos, Solitons & Fractals. 2020;140:110127.
   Web of Science ®Google Scholar
• Ahmad SB, Rashid SM, Wali AF, Ali S, Rehman MU, Maqbool MT, Nadeem A, Ahmad SF, Siddiqui N. Myricetin (3,3 ′ ,4 ′ ,5,5 ′ ,7-hexahydroxyflavone) prevents ethanol-induced biochemical and inflammatory damage in the liver of Wistar rats. Hum Exp Toxicol. 2022;41:41. doi:10.1177/09603271211066843.
   Web of Science ®Google Scholar
• Sperkova K, Anderson P, Llopis EJ, Sarangi PK. Alcohol policy measures are an ignored catalyst for achievement of the sustainable development goals. PLoS One. 2022;17:e0267010. doi:10.1371/journal.pone.0267010.
   PubMed Web of Science ®Google Scholar
• Bull C, Freitas KC, Zou S, Poland RS, Syed WA, Urban DJ, Minter SC, Shelton KL, Hauser KF, Negus SS, et al. Rat nucleus accumbens core astrocytes modulate reward and the motivation to self-administer ethanol after abstinence. Neuropsychopharmacology. 2014;39:2835–45. doi:10.1038/npp.2014.135.
   PubMed Web of Science ®Google Scholar
• Naglich AC, Bozeman S, Sherwood Brown E, Adinoff B. Effect of selective serotonin reuptake inhibitors on healthcare utilization in patients with post-traumatic stress disorder and alcohol use disorder. Alcohol Alcohol. 2019;54:428–34. doi:10.1093/alcalc/agz045.
   PubMed Web of Science ®Google Scholar
• Ait-Daoud N, Blevins D, Khanna S, Sharma S, Holstege CP, Amin P. Women and addiction: an update. Med Clin North Am. 2019;103:699–711. doi:10.1016/j.mcna.2019.03.002.
   PubMed Web of Science ®Google Scholar
• Thorberg FA, Young RM, Lyvers M, Sullivan KA, Hasking P, London ED, Tyssen R, Connor JP, Feeney GFX. Alexithymia in relation to alcohol expectancies in alcohol-dependent outpatients. Psychiatry Res. 2016;236:186–88. doi:10.1016/j.psychres.2016.01.016.
   PubMed Web of Science ®Google Scholar
• McDonell MG, Skalisky J, Burduli E, Foote A, Granbois A, Smoker K, Hirchak K, Herron J, Ries RK, Echo-Hawk A, et al. The rewarding recovery study: a randomized controlled trial of incentives for alcohol and drug abstinence with a rural American Indian community. Addiction. 2021;116:1569–79. doi:10.1111/add.15349.
   PubMed Web of Science ®Google Scholar
• Allahverdiyeva S, Keskin E, Yörük İ, Yardım Y. Electrochemical determination of flavonoid fisetin in commercial dietary supplements using a boron-doped diamond electrode. ChemistrySelect. 2023;8. doi:10.1002/slct.202300125.
   PubMed Web of Science ®Google Scholar
• Kashyap D, Garg VK, Tuli HS, Yerer MB, Sak K, Sharma AK, Kumar M, Aggarwal V, Sandhu SS. Fisetin and quercetin: promising flavonoids with chemopreventive potential. Biomolecules. 2019;9:174. doi:10.3390/biom9050174.
   PubMed Web of Science ®Google Scholar
• Grynkiewicz G, Demchuk OM. New perspectives for fisetin. Front Chem. 2019;7:697. doi:10.3389/fchem.2019.00697.
   PubMed Web of Science ®Google Scholar
• Ahmad A, Ali T, Park HY, Badshah H, Rehman SU, Kim MO. Neuroprotective effect of fisetin against amyloid-beta-induced cognitive/synaptic dysfunction, neuroinflammation, and neurodegeneration in adult mice. Mol Neurobiol. 2017;54:2269–2285. doi:10.1007/s12035-016-9795-4.
   PubMed Web of Science ®Google Scholar
• Wang Y, Wang B, Lu J, Shi H, Gong S, Wang Y, Hamdy RC, Chua BHL, Yang L, Xu X. Fisetin provides antidepressant effects by activating the tropomyosin receptor kinase B signal pathway in mice. J Neurochem. 2017;143:561–68. doi:10.1111/jnc.14226.
   PubMed Web of Science ®Google Scholar
• Khatoon S, Agarwal NB, Samim M, Alam O. Neuroprotective effect of fisetin through suppression of IL-1R/TLR axis and apoptosis in pentylenetetrazole-induced kindling in mice. Front Neurol. 2021;12:689069. doi:10.3389/fneur.2021.689069.
   PubMed Web of Science ®Google Scholar
• Jin T, Kim OY, Shin MJ, Choi EY, Lee SS, Han YS, Chung JH. Fisetin up-regulates the expression of adiponectin in 3T3-L1 adipocytes via the activation of silent mating type information regulation 2 homologue 1 (SIRT1)-deacetylase and peroxisome proliferator-activated receptors (PPARs). J Agric Food Chem. 2014;62:10468–10474. doi:10.1021/jf502849j.
   PubMed Web of Science ®Google Scholar
• Ozturk H, Basoglu H, Yorulmaz N, Aydin-Abidin S, Abidin I. Fisetin decreases the duration of ictal-like discharges in mouse hippocampal slices. J Biol Phys. 2022;48:355–68. doi:10.1007/s10867-022-09612-0.
   PubMed Web of Science ®Google Scholar
• Zhao X, Li XL, Liu X, Wang C, Zhou DS, Ma Q, Zhou WH, Hu ZY. Antinociceptive effects of fisetin against diabetic neuropathic pain in mice: engagement of antioxidant mechanisms and spinal GABAA receptors. Pharmacol Res. 2015;102:286–97. doi:10.1016/j.phrs.2015.10.007.
   PubMed Web of Science ®Google Scholar
• Chiruta C, Schubert D, Dargusch R, Maher P. Chemical modification of the multitarget neuroprotective compound fisetin. J Med Chem. 2012;55:378–89. doi:10.1021/jm2012563.
   PubMed Web of Science ®Google Scholar
• Erdozain AM, Callado LF. Neurobiological alterations in alcohol addiction: a review. Adicciones. 2014;26:360–370. doi:10.20882/adicciones.40.
   PubMed Web of Science ®Google Scholar
• Tzschentke TM. REVIEW on CPP: measuring reward with the conditioned place preference (CPP) paradigm: update of the last decade. Addict Biol. 2007;12:227–462. doi:10.1111/j.1369-1600.2007.00070.x.
   PubMed Web of Science ®Google Scholar
• Ray LA, Meredith LR, Kiluk BD, Walthers J, Carroll KM, Magill M. Combined pharmacotherapy and cognitive behavioral therapy for adults with alcohol or substance use disorders: a systematic review and meta-analysis. JAMA Netw Open. 2020;3:e208279. doi:10.1001/jamanetworkopen.2020.8279.
   PubMed Web of Science ®Google Scholar
• Swift RM, Aston ER. Pharmacotherapy for alcohol use disorder: current and emerging therapies. Harv Rev Psychiatry. 2015;23:122. doi:10.1097/HRP.0000000000000079.
   PubMed Web of Science ®Google Scholar
• Touil YS, Auzeil N, Boulinguez F, Saighi H, Regazzetti A, Scherman D, Chabot GG. Fisetin disposition and metabolism in mice: identification of geraldol as an active metabolite. Biochem Pharmacol. 2011;82:1731–39. doi:10.1016/j.bcp.2011.07.097.
   PubMed Web of Science ®Google Scholar
• Allahverdiyev O, Nurten A, Enginar N. Assessment of rewarding and reinforcing properties of biperiden in conditioned place preference in rats. Behav Brain Res. 2011;225:642–45. doi:10.1016/j.bbr.2011.07.050.
   PubMed Web of Science ®Google Scholar
• Yunusoğlu O. Linalool attenuates acquisition and reinstatement and accelerates the extinction of nicotine-induced conditioned place preference in male mice. Am J Drug Alcohol Abuse. 2021;47:422–32. doi:10.1080/00952990.2021.1898627.
   PubMed Web of Science ®Google Scholar
• McKendrick G, Graziane NM. Drug-induced conditioned place preference and its practical use in substance use disorder research. Front Behav Neurosci. 2020;14:582147. doi:10.3389/fnbeh.2020.582147.
   PubMed Web of Science ®Google Scholar
• Pautassi RM, Wille-Bille A, Fernández MS, Fabio MC. Ethanol intake on preclinical models: methods of assessment and effects on dopamine signaling. In: Dopaminergic system function and dysfunction: experimental approaches. Springer; 2023:163–181.
   Google Scholar
• Yunusoğlu O. Evaluation of the effects of quercetin on the rewarding property of ethanol in mice. Neurosci Lett. 2022;768:136383. doi:10.1016/j.neulet.2021.136383.
   PubMed Web of Science ®Google Scholar
• Ahmad A, Ali T, Rehman SU, Kim MO. Phytomedicine-based potent antioxidant, fisetin protects CNS-Insult LPS-Induced oxidative stress-mediated neurodegeneration and memory impairment. J Clin Med. 2019;8:850. doi:10.3390/jcm8060850.
   PubMed Web of Science ®Google Scholar
• Sklenarik SM, Burrows CN, Astur RS. Conditioned place preferences for virtual alcohol cues. Behav Brain Res. 2023;438:114176. doi:10.1016/j.bbr.2022.114176.
   PubMed Web of Science ®Google Scholar
• Berardo LR, Fabio MC, Pautassi RM. Post-weaning environmental enrichment, but not chronic maternal isolation, enhanced ethanol intake during periadolescence and early adulthood. Front Behav Neurosci. 2016;10:195. doi:10.3389/fnbeh.2016.00195.
   PubMed Web of Science ®Google Scholar
• Lee JY, Choe ES, Yang CH, Choi KH, Cheong JH, Jang CG, Seo JW, Yoon SS. The mGlur5 antagonist MPEP suppresses the expression and reinstatement, but not the acquisition, of the ethanol-conditioned place preference in mice. Pharmacol Biochem Behav. 2016;140:33–38. doi:10.1016/j.pbb.2015.10.015.
   PubMed Web of Science ®Google Scholar
• Li X, Meng L, Huang K, Wang H, Li D. Environmental enrichment blocks reinstatement of ethanol-induced conditioned place preference in mice. Neurosci Lett. 2015;599:92–96. doi:10.1016/j.neulet.2015.05.035.
   PubMed Web of Science ®Google Scholar
• Acevedo MB, Nizhnikov ME, Spear NE, Molina JC, Pautassi RM. Ethanol-induced locomotor activity in adolescent rats and the relationship with ethanol-induced conditioned place preference and conditioned taste aversion. Dev Psychobiol. 2013;55:429–42. doi:10.1002/dev.21048.
   PubMed Web of Science ®Google Scholar
• Ferreira SEM, Soares LM, Lira CR, Yokoyama TS, Engi SA, Cruz FC, Leão RM. Ethanol-induced locomotor sensitization: neuronal activation in the nucleus accumbens and medial prefrontal cortex. Neurosci Lett. 2021;749:135745. doi:10.1016/j.neulet.2021.135745.
   PubMed Web of Science ®Google Scholar
• Swift RM, Aston ER. Pharmacotherapy for alcohol use disorder: current and emerging therapies. Harv Rev Psychiatry. 2015;23:122–33. doi:10.1097/HRP.0000000000000079.
   PubMed Web of Science ®Google Scholar
• Johnson KA, Liput DJ, Homanics GE, Lovinger DM. Age-dependent impairment of metabotropic glutamate receptor 2-dependent long-term depression in the mouse striatum by chronic ethanol exposure. Alcohol (Fayetteville, NY). 2020;82:11–21.
   PubMed Web of Science ®Google Scholar
• Ivan Ezquerra-Romano I, Lawn W, Krupitsky E, Morgan CJA. Ketamine for the treatment of addiction: evidence and potential mechanisms. Neuropharmacology. 2018;142:72–82. doi:10.1016/j.neuropharm.2018.01.017.
   PubMed Web of Science ®Google Scholar
• Chen BP, Huang XX, Dong DM, Wu H, Zhu TQ, Wang BF. The role of NMDA receptors in rat propofol self-administration. BMC Anesthesiol. 2020;20:149. doi:10.1186/s12871-020-01056-0.
   PubMed Web of Science ®Google Scholar
• Domi E, Domi A, Adermark L, Heilig M, Augier E. Neurobiology of alcohol seeking behavior. J Neurochem. 2021;157:1585–614. doi:10.1111/jnc.15343.
   PubMed Web of Science ®Google Scholar
• Pautassi RM, Wille-Bille A, Fernández MS, Fabio MC. Ethanol intake on preclinical models: methods of assessment and effects on dopamine signaling. In: Dopaminergic system function and dysfunction: experimental approaches. Springer; 2022:163–181.
   Google Scholar
• Biała G, Kotlińska J. Blockade of the acquisition of ethanol-induced conditioned place preference by N-methyl-D-aspartate receptor antagonists. Alcohol Alcohol (Oxford, Oxfordshire). 1999;34:175–182. doi:10.1093/alcalc/34.2.175.
   PubMed Web of Science ®Google Scholar
• Athira K, Das SS, Swick A, Krishnakumar I, Vahab AA. Oral bioavailability and neuroprotective effect of a novel food-grade formulation of fisetin using fenugreek-galactomannan hydrogel scaffolds. PharmaNutrition. 2023;23:100329. doi:10.1016/j.phanu.2023.100329.
   Web of Science ®Google Scholar
• Raygude KS, Kandhare AD, Ghosh P, Bodhankar SL. Anticonvulsant effect of fisetin by modulation of endogenous biomarkers. Biomed & Preventive Nutr. 2012;2:215–22. doi:10.1016/j.bionut.2012.04.005.
   Google Scholar
• Matheson J, Le Foll B. Therapeutic potential of Peroxisome Proliferator-Activated Receptor (PPAR) agonists in substance use disorders: a synthesis of preclinical and human evidence. Cells. 2020;9:1196. doi:10.3390/cells9051196.
   PubMed Web of Science ®Google Scholar
• Le Foll B, Di Ciano P, Panlilio LV, Goldberg SR, Ciccocioppo R. Peroxisome proliferator-activated receptor (PPAR) agonists as promising new medications for drug addiction: preclinical evidence. Curr Drug Targets. 2013;14:768–76. doi:10.2174/1389450111314070006.
   PubMed Web of Science ®Google Scholar
• Garg S, Khan SI, Malhotra RK, Sharma MK, Kumar M, Kaur P, Nag TC, Bhatia J, Arya DS. The molecular mechanism involved in cardioprotection by the dietary flavonoid fisetin as an agonist of PPAR-γ in a murine model of myocardial infarction. Arch Biochem Biophys. 2020;694:108572. doi:10.1016/j.abb.2020.108572.
   PubMed Web of Science ®Google Scholar
• Pei F, Pei H, Su C, Du L, Wang J, Xie F, Yin Q, Gao Z. Fisetin alleviates Neointimal Hyperplasia via PPARγ/PON2 antioxidative pathway in SHR rat artery injury model. Oxid Med Cell Longev. 2021;2021:6625517. doi:10.1155/2021/6625517.
   PubMed Web of Science ®Google Scholar
• Volkow ND, Michaelides M, Baler R. The neuroscience of drug reward and addiction. Physiol Rev. 2019;99:2115–40. doi:10.1152/physrev.00014.2018.
   PubMed Web of Science ®Google Scholar
• Das SK, Vasudevan DM. Alcohol-induced oxidative stress. Life Sci. 2007;81:177–87. doi:10.1016/j.lfs.2007.05.005.
   PubMed Web of Science ®Google Scholar
• Akünal Türel C, Yunusoğlu O. Oleanolic acid suppresses pentylenetetrazole-induced seizure in vivo. Int J Environ Health Res. 2023;33:529–40. doi:10.1080/09603123.2023.2167947.
   PubMed Web of Science ®Google Scholar
• Haorah J, Ramirez SH, Floreani N, Gorantla S, Morsey B, Persidsky Y. Mechanism of alcohol-induced oxidative stress and neuronal injury. Free Radic Biol Med. 2008;45:1542–50. doi:10.1016/j.freeradbiomed.2008.08.030.
   PubMed Web of Science ®Google Scholar
• Ergul Erkec O, Yunusoglu O, Huyut Z. Evaluation of repeated ghrelin administration on seizures, oxidative stress and neurochemical parameters in pentyleneterazole induced kindling in rats. Int J Neurosci. 2022;1–9. doi:10.1080/00207454.2022.2107516.
   PubMed Web of Science ®Google Scholar
• Naeimi AF, Alizadeh M. Antioxidant properties of the flavonoid fisetin: an updated review of in vivo and in vitro studies. TRends in Food sci Technol. 2017;70:34–44. doi:10.1016/j.tifs.2017.10.003.
   Web of Science ®Google Scholar
• Quintanilla ME, Morales P, Ezquer F, Ezquer M, Herrera-Marschitz M, Israel Y. Commonality of ethanol and nicotine reinforcement and relapse in wistar-derived UChB rats: inhibition by N-Acetylcysteine. Alcohol Clin Exp Res. 2018;42:1988–99. doi:10.1111/acer.13842.
   PubMed Web of Science ®Google Scholar
• Xu C, Li R, Wu J. Effects of Yuanhu- Zhitong tablets on alcohol-induced conditioned place preference in mice. Biomed Pharmacother Biomed Pharmacotherapie. 2021;133:110962. doi:10.1016/j.biopha.2020.110962.
   PubMed Web of Science ®Google Scholar
• Yunusoglu O, Bukhari A, Turel C, Demirkol M, Berköz M, AKkan A. Investigation of the pharmacological potential of myricetin on alcohol addiction in mice. J Res Pharm. 2022;26:722–733. doi:10.29228/jrp.170.
   Google Scholar
• ElShebiney S, Elgohary R, El-Shamarka M, Mowaad N, Abulseoud OA. Natural polyphenols-resveratrol, quercetin, magnolol, and β-catechin-block certain aspects of heroin addiction and modulate striatal IL-6 and TNF-α. Toxics. 2023;11. doi:10.3390/toxics11040379.
   PubMed Web of Science ®Google Scholar
• Li Y, Yu L, Zhao L, Zeng F, Liu QS. Resveratrol modulates cocaine-induced inhibitory synaptic plasticity in VTA dopamine neurons by inhibiting phosphodiesterases (PDEs). Sci Rep. 2017;7:15657. doi:10.1038/s41598-017-16034-9.
   PubMed Web of Science ®Google Scholar
• Etemad L, Farkhari H, Alavi MS, Roohbakhsh A. The effect of dihydromyricetin, a natural flavonoid, on morphine-induced conditioned place preference and physical dependence in mice. Drug Res (Stuttg). 2020;70:410–16. doi:10.1055/a-1206-6757.
   PubMed Web of Science ®Google Scholar
• Osman A, Hofford RS, Meckel KR, Dave YA, Zeldin SM, Shipman AL, Lucerne KE, Trageser KJ, Oguchi T, Kiraly DD. Dietary polyphenols drive dose-dependent behavioral and molecular alterations to repeated morphine. Sci Rep. 2023;13:12223. doi:10.1038/s41598-023-39334-9.
   PubMed Web of Science ®Google Scholar
• Lu L, Liu Y, Zhu W, Shi J, Liu Y, Ling W, Kosten TR. Traditional medicine in the treatment of drug addiction. Am J Drug Alcohol Abuse. 2009;35:1–11. doi:10.1080/00952990802455469.
   PubMed Web of Science ®Google Scholar
• Finn DA. The endocrine system and alcohol drinking in females. Alcohol Res. 2019;40:1–20. doi:10.35946/arcr.v40.2.02.
   Web of Science ®Google Scholar
• Alavi M, Ryabinin AE, Helms ML, Nipper MA, Devaud LL, Finn DA. Sensitivity and resilience to predator stress-enhanced ethanol drinking is associated with Sex-dependent differences in stress-regulating systems. Front Behav Neurosci. 2022;16. doi:10.3389/fnbeh.2022.834880.
   PubMed Web of Science ®Google Scholar
• Vickers-Smith R, Justice AC, Becker WC, Rentsch CT, Curtis B, Fernander A, Hartwell EE, Ighodaro ET, Kember RL, Tate J, et al. Racial and ethnic bias in the diagnosis of alcohol use disorder in veterans. Am J Psychiatry. 2023;180:426–36. doi:10.1176/appi.ajp.21111097.
   PubMed Web of Science ®Google Scholar
• Flores-Bonilla A, Richardson HN. Sex differences in the neurobiology of alcohol use disorder. Alcohol Res. 2020;40:4. doi:10.35946/arcr.v40.2.04.
   Google Scholar
• Becker JB, McClellan ML, Reed BG. Sex differences, gender and addiction. J Neurosci Res. 2017;95:136–47. doi:10.1002/jnr.23963.
   PubMed Web of Science ®Google Scholar
• Becker JB, Koob GF, Gottesman MM. Sex differences in animal models: focus on addiction. Pharmacol Rev. 2016;68:242–63. doi:10.1124/pr.115.011163.
   PubMed Web of Science ®Google Scholar
• Salguero A, Barey A, Virgolini RG, Mujica V, Fabio MC, Miranda-Morales RS, Marengo L, Camarini R, Pautassi RM. Juvenile variable stress modulates, in female but not in male Wistar rats, ethanol intake in adulthood. Neurotoxicol Teratol. 2023;100:107306. doi:10.1016/j.ntt.2023.107306.
   PubMed Web of Science ®Google Scholar